Fluid Therapy Flashcards
define osmosis
the movement of water across a semi-permeable membrane from high water activity to low water activity
define osmolality
the concentration of a solution expressed as the total number of solute particles per litre
what are electrolytes?
minerals dissolved into ions
define tonicity
the measure of osmotic pressure of two solutions separated by a semi permeable membrane
define isotonic
two solutions have the same concentration of impermeable solutes
define hypotonic
the solution contains a lower concentration of impermeable solutes than the body (cell) fluid so will move into the body (cell) and can cause lysis
define hypertonic
the solution contains a higher concentration of impermeable solutes than the body (cell) fluid so will draw water out of body (cell) tissues
name 2 examples of a normal fluid intake
eating and drinking
name 2 examples of normal fluid outgoing
urination and defecation
name 2 examples of abnormal fluid intake
water deprivation and anesthesia
name 2 examples of abnormal fluid outgoing
vomiting and haemorrhage
what may fluid loss be caused by?
dehydration and hypovolaemia
what are two other potential causes of fluid imbalance?
electrolyte imbalance and altered fluid distribution (change in oncotic pressures e.g. loss of albumin)
define dehydration
loss of fluid from extravascular space
what would be the clinical findings of 0-4% dehydration?
none (very few)
what would be the clinical findings of 4-6% dehydration?
tacky mucous membranes
what would be the clinical findings of 6-8% dehydration?
loss of skin turgor (skin tent becomes less elastic), dry mucous membranes
what would be the clinical findings of 8-10% dehydration?
loss of skin turgor (skin tent becomes less elastic), dry mucous membranes, sunken eyes
what would be the clinical findings of 10-12% dehydration?
persistant skin tent, dry mucous membranes, retracted globe, dull corneas, pulse deficits (hypovolaemia)
define hypovolaemia
reduction in blood volume or fluid in the intravascular space
what are the clinical signs of mild (compensated) hypovolaemia?
mild tachycardia, pinker than normal mucous membranes, increased (<1 second) capillary refill time, bounding pulse
define compensating/compensated
patients body is able to correct fluid loss using normal physiological processes (e.g. vasoconstriction, increased HR)
define decompensated/decompensating
body is unable to keep up and maintain fluid volume
what are the clinical signs of severe (decompensated) hypovolaemia?
severe tachycardia, white/grey mucous membranes, >2seconds (prolonged) capillary refill time, poor/thready pulse
how does the presentation of severe (decompensated) hypovolaemia differ in cats?
causes bradycardia not tachycardia
what are crystalliod fluids?
solutions which contain diluted minerals known as electrolytes
what are the 3 main types of crystalloid fluids?
replacement
maintenance
hypertonic
give 3 examples of replacement crystalloid fluids
Hartmann’s
Lactated Ringers
0.9% NaCl (normal saline)
what is the tonicity of replacement crystalloid fluids compared to ECF?
isotonic - they will not cause any fluid movement and so increase the volume of intravascular space and ECF
give an example of maintenance crystalloid fluids
0.45% NaCl + 2.5% dextrose
what is the tonicity of maintenance crystalloid fluids, such as 0.45% NaCl + 2.5% dextrose, compared to ECF?
hypotonic - fluid will move into the intracellular space
how does 0.45% NaCl + 2.5% dextrose avoid the issue of cell lysis associated with hypotonic solutions?
the solution remains isotonic until the dextrose is metabolised when it then becomes hypotonic. Shortens time cells are exposed to hypotonic solution
give an example of a hypertonic crystalloid fluid
7.2% NaCl (hypertonic saline)
what is the effect on cells of hypertonic saline (7.2% NaCl)?
pulls fluid from ICF into intravascular space
when must hypertonic saline (7.2% NaCl) be avoided?
dehydration due to its likelihood to worsen it
when can hypertonic saline (7.2% NaCl) be used effectively?
resuscitation of hypovolaemic cases
what are colloids?
large molecules that increase the oncotic pressure of plasma and so hold fluid in the intravascular space and increase volume
what are colloids introduced in?
fluid
when are colloids useful?
hypovolaemia
give 2 synthetic/artificial colloids
dextrans and gelatins
what are natural colloids?
blood products, frozen plasma or whole blood
what are the 5 methods of administration of fluids?
intravenous, subcutaneous, intra-osseus, oral, intraperitoneal
which is the most common method of fluid administration?
IV - fast acting and large volumes
when is subcutaneous most useful?
mild dehydration or feline kidney disease
when is intra-osseus fluid given?
in puppies or kittens where their vessels are small and may be collapsed if dehydrated
what is the issue with oral administration of fluids?
relies on the patient drinking
when are intraperitoneal fluids given?
to small furries
what are the slowest acting methods of fluid administration?
sub-Q and intraperitoneal
what are the 5 Rs of a fluid plan?
resuscitation routine maintenance replacement redistribution re-assessment
what is the amount of fluids required for routine maintenance?
50ml/kg/day
what are the 3 most common types of giving set?
standard, pediatric burette, blood giving
what is the difference between a standard giving set and a paediatric burette?
paediatric burette is smaller and offers much more control
what does a blood giving set have that others do not?
filter to trap blood clots
what differs between giving sets?
drip factors
how should dehydration deficit be calculated?
dehydration deficit = %dehydration x BW(kg) x 10
how should ongoing losses be calculated?
ongoing losses = 4ml x number of vomit/diarrhea episodes x BW(kg)
what is the maintenance of fluid calculation?
maintenance = 50 ml/kg/day x BW(kg)
how should a patients fluid requirement over 24 hours be calculated?
sum of:
dehydration deficit, ongoing losses and maintenance
how can we convert fluid requirement over 24 hours to drip rate?
convert total fluid requirement over 24 hours to ml/min by dividing by 24 (hours) and then 60 (minutes).
how should drops per minute be calculated from m per minute?
drops per minute = millilitres per minute x giving set factor
what is the usual value of a giving set factor?
20 or 60
how is the final drip rate (seconds/drop) calculated from drops per minute?
drip rate = 60 /drops per minute