First Aid pg 624-633 Rapid Review Flashcards
Abdominal pain, ascites, hepatomegaly
Budd-Chiari syndrome (posthepatic venous thrombosis)
Adrenal hemorrhage, hypotension, DIC
Waterhouse-Friderichsen syndrome (meningococcemia)
Anaphylaxis following blood transfusion
IgA def
Anterior “drawer sign” ⊕
ACL injury
Back pain, fever, night sweats
Pott disease (vertebral TB)
Bilateral hilar adenopathy, uveitis
Sarcoidosis (noncaseating granulomas)
Black eschar on face of patient with diabetic ketoacidosis
Mucor or Rhizopus fungal infection
Bounding pulses, wide pulse pressure, diastolic heart murmur, head bobbing
AR
Café-au-lait spots (unilateral), polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities
McCune-Albright syndrome (mosaic G-protein signaling mutation)
Calf pseudohypertrophy
Muscular dystrophy (most commonly Duchenne)
Cervical lymphadenopathy, desquamating rash, coronary aneurysms, red conjunctivae and tongue, hand-foot changes
Kawasaki disease (treat with IVIG and aspirin)
“Cherry-red spots” on macula
Tay-Sachs (ganglioside accumulation) or Niemann-Pick (sphingomyelin accumulation), central retinal artery occlusion
Child uses arms to stand up from squat
Duchenne muscular dystrophy (Gowers sign)
Chorioretinitis, hydrocephalus, intracranial calcifications
Congenital Toxoplasmosis
Conjugate horizontal gaze palsy, horizontal diplopia
MLF issue
Cutaneous/dermal edema due to connective tissue deposition
Myxedema (caused by hypothyroidism, Graves disease
[pretibial])
Cutaneous flushing, diarrhea, bronchospasm
Carcinoid syndrome (right-sided cardiac valvular lesions, 5-HIAA)
Dry eyes, dry mouth, arthritis
Sjogren’s
Episodic vertigo, tinnitus, hearing loss
Meniere disease
Erythroderma, lymphadenopathy, hepatosplenomegaly,
atypical T cells
Mycosis fungoides (cutaneous T-cell lymphoma) or Sézary syndrome (mycosis fungoides + malignant T cells in blood
Fever, chills, headache, myalgia following antibiotic
treatment for syphilis
Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in endotoxin release)
Fibrous plaques in soft tissue of penis with abnormal
curvature
Peyronie disease
Hamartomatous GI polyps, hyperpigmentation of
mouth/feet/hands/genitalia
Peutz-Jeghers syndrome (inherited, benign polyposis can cause bowel obstruction; cancer risk, mainly GI)
Hepatosplenomegaly, pancytopenia, osteoporosis, aseptic necrosis of femoral head, bone crises
Gaucher disease
Hereditary nephritis, sensorineural hearing loss,
cataracts
Alports
Hyperphagia, hypersexuality, hyperorality,
hyperdocility
Klüver-Bucy syndrome (bilateral amygdala lesion)
Hyperreflexia, hypertonia, Babinski sign present
UMN damage
Hyporeflexia, hypotonia, atrophy, fasciculations
LMN damage
Infant with hypoglycemia, hepatomegaly
Cori disease (debranching enzyme deficiency) or Von Gierke disease (glucose-6-phosphatase deficiency, more severe)
Lucid interval after traumatic brain injury
Epidural hematoma
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth
Gardner syndrome
Neonate with arm paralysis following difficult birth
Erb-Duchenne palsy (superior trunk [C5–C6] brachial plexus injury: “waiter’s tip”)
Painful blue fingers/toes, hemolytic anemia
Cold agglutinin disease (autoimmune hemolytic
anemia caused by Mycoplasma pneumoniae, infectious
mononucleosis, CLL)
Painful fingers/toes changing color from blue to white to redwith cold or stress
Raynaud phenomenon
Painful, raised red lesions on pads of fingers/toes
Osler nodes (infective endocarditis, immune complex deposition)
Painless erythematous lesions on palms and soles
Janeway lesions (infective endocarditis, septic emboli/ microabscesses)
Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria
Henoch-Schönlein purpura (IgA vasculitis affecting skin and kidneys)
Polyuria, renal tubular acidosis type II, growth failure,
electrolyte imbalances, hypophosphatemic rickets
Fanconi syndrome (multiple combined dysfunction of the proximal convoluted tubule)
Pruritic, purple, polygonal planar papules and plaques (6 P’s)
Lichen planus
Pupil accommodates but doesn’t react
Neurosyphilis (Argyll Robertson pupil)
Rash on palms and soles
Coxsackie A, 2° syphilis, Rocky Mountain spotted fever
Renal cell carcinoma (bilateral), hemangioblastomas,
angiomatosis, pheochromocytoma
von Hippel-Lindau disease (dominant tumor suppressor gene mutation)
Retinal hemorrhages with pale centers
Roth spots (bacterial endocarditis)
Short stature, café au lait spots, thumb/radial defects,
incidence of tumors/leukemia, aplastic anemia
Fanconi anemia
Skin hyperpigmentation, hypotension, fatigue
1° adrenocortical insufficiency (eg, Addison disease) causes ACTH and α-MSH production)
“Strawberry tongue”
Scarlet fever, Kawasaki disease
Swollen, hard, painful finger joints
Osteoarthritis (osteophytes on PIP [Bouchard nodes], DIP [Heberden nodes])
Telangiectasias, recurrent epistaxis, skin discoloration,
arteriovenous malformations, GI bleeding, hematuria
Osler-Weber-Rendu syndrome
Unilateral facial drooping involving forehead
LMN facial nerve (CN VII) palsy; UMN lesions spare the
forehead
Vascular birthmark (port-wine stain) of the face
Nevus flammeus (benign, but associated with Sturge-Weber syndrome)
inc AFP in amniotic fluid/maternal serum
Dating error, anencephaly, spina bifida (neural tube defects)
Anticentromere antibodies
Scleroderma (CREST)
Anti-desmoglein (anti-desmosome) antibodies
Pemphigus vulgaris (blistering)
Anti–glomerular basement membrane antibodies
Goodpasture syndrome (glomerulonephritis and hemoptysis)
Antihistone antibodies
Drug-induced SLE (eg, hydralazine, isoniazid, phenytoin,
procainamide)
Anti-IgG antibodies
Drug-induced SLE (eg, hydralazine, isoniazid, phenytoin,
procainamide)
Antimitochondrial antibodies (AMAs)
1° biliary cirrhosis (female, cholestasis, portal hypertension)
Antineutrophil cytoplasmic antibodies (ANCAs)
SLE (HS-III)
Anti-topoisomerase antibodies
Diffuse systemic scleroderma
Azurophilic peroxidase ⊕ granular inclusions in granulocytes
and myeloblasts
Auer rods (AML)
Bacitracin response
Sensitive: S pyogenes (group A); resistant: S agalactiae (group
B)
Basophilic nuclear remnants in RBCs
Howell-Jolly bodies (due to splenectomy or nonfunctional
spleen)
Basophilic stippling of RBCs
Lead poisoning or sideroblastic anemia
Branching gram ⊕ rods with sulfur granules
Actinomyces israelii
“Brown” tumor of bone
Hyperparathyroidism or osteitis fibrosa cystica (deposited
hemosiderin from hemorrhage gives brown color)
Cardiomegaly with apical atrophy
Hyperparathyroidism or osteitis fibrosa cystica (deposited hemosiderin from hemorrhage gives brown color)
Circular grouping of dark tumor cells surrounding pale
neurofibrils
Homer-Wright rosettes (neuroblastoma,medulloblastoma)
Degeneration of dorsal column fibers
Tabes dorsalis (3° syphilis), subacute combined degeneration(dorsal columns, lateral corticospinal, spinocerebellar tracts affected)
Desquamated epithelium casts in sputum
Curschmann spirals (bronchial asthma; can result in whorled mucous plugs)