First Aid pg 624 - 633 Part II Rapid Review Flashcards

1
Q

Disarrayed granulosa cells arranged around collections of eosinophilic fluid

A

Call-Exner bodies (granulosa cell tumor of the ovary)

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2
Q

Dysplastic squamous cervical cells with “raisinoid” nuclei and hyperchromasia

A

Koilocytes (HPV: predisposes to cervical cancer)

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3
Q

Electrical alternans (alternating amplitude on EKG)

A

Pericardial tamponade

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4
Q

Eosinophilic cytoplasmic inclusion in liver cell vs neuron

A

Liver cell - Mallory body

Neuron - Lewy body (parkinson’s, lewy body)

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5
Q

Eosinophilic cytoplasmic inclusion in liver cell

A

Councilman body (viral hepatitis, yellow fever), represents hepatocyte undergoing apoptosis

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6
Q

Glomerulus-like structure surrounding vessel in germ cells

A

Schiller-Duval bodies (yolk sac tumor)

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7
Q

hCG elevated

A

Choriocarcinoma, hydatidiform mole (occurs with and

without embryo), multiple pregnancy

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8
Q

High level of d-dimers

A

DVT, PE, DIC

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9
Q

“Honeycomb lung” on x-ray or CT

A

Interstitial pulmonary fibrosis

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10
Q

Intranuclear eosinophilic droplet-like bodies

A

Cowdry type A bodies (HSV or VZV)

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11
Q

Large granules in phagocytes, immunodeficiency

A

Chédiak-Higashi disease (congenital failure of phagolysosome formation)

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12
Q

Mammary gland (“blue domed”) cyst

A

Fibrocystic change of the breast

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13
Q

Mucin-filled cell with peripheral nucleus

A

“Signet ring” (gastric carcinoma)

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14
Q

Nodular hyaline deposits in glomeruli

A

Kimmelstiel-Wilson nodules (diabetic nephropathy)

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15
Q

Optochin response

A

Sensitive: S pneumoniae; resistant: viridans streptococci

S mutans, S sanguis

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16
Q

Polished, “ivory-like” appearance of bone at cartilage erosion

A

Eburnation (osteoarthritis resulting in bony sclerosis)

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17
Q

Psammoma bodies

A

Meningiomas, papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of the endometrium and ovary

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18
Q

Pseudopalisading tumor cells on brain biopsy

A

Glioblastoma multiforme

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19
Q

Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells

A

Reinke crystals (Leydig cell tumor)

20
Q

Recurrent infections, eczema, thrombocytopenia

A

Wiskott-Aldrich syndrome

21
Q

“Soap bubble” in femur or tibia on x-ray

A

Giant cell tumor of bone (generally benign)

22
Q

“Steeple” sign on frontal CXR

A

Croup (parainfluenza virus)

23
Q

Thrombi made of white/red layers

A

Lines of Zahn (arterial thrombus, layers of platelets/RBCs)

24
Q

“Thumb sign” on lateral neck x-ray

A

Epiglottitis (Haemophilus influenzae)

25
Q

Thyroid-like appearance of kidney

A

Chronic pyelonephritis (usually due to recurrent infections)

26
Q

inc  uric acid levels

A

Gout, Von Gierke, Lesch-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics

27
Q

Acute promyelocytic leukemia (M3)

A

All-trans retinoic acid

28
Q

ADHD

A

Methylphenidate, CBT, atomoxetine, guanfacine, clonidine

29
Q

Alcoholism

A

Disulfiram, acamprosate, naltrexone, supportive care

30
Q

psychotherapy, mirtazapine

A

Anorexia

31
Q

Arrhythmia in damaged cardiac tissue

A

Class IB antiarrhythmic (lidocaine, mexiletine)

32
Q

Benign prostatic hyperplasia

A

α1-antagonists, 5α-reductase inhibitors, PDE-5 inhibitors

33
Q

Breast cancer in postmenopausal woman

A

Aromatase inhibitor (anastrozole)

34
Q

Candida albicans

A

Topical azoles (vaginitis); nystatin, fluconazole, caspofungin (oral/esophageal); fluconazole, caspofungin, amphotericin B (systemic)

35
Q

Chlamydia trachomatis

A

Doxycycline (+ ceftriaxone for gonorrhea coinfection),

erythromycin eye drops (prophylaxis in infants)

36
Q

Chronic myelogenous leukemia

A

Imatinib

37
Q

Crohn disease

A

Corticosteroids, infliximab, azathioprine, adalimumab.

38
Q

Diabetes insipidus

A

Desmopressin (central); hydrochlorothiazide, indomethacin, amiloride (nephrogenic)

39
Q

Enterococci

A

Vancomycin, aminopenicillins/cephalosporins

40
Q

ER ⊕ breast cancer

A

Tamoxifen

41
Q

Heparin reversal

A

Protamine sulfate

42
Q

HER2/neu ⊕ breast cancer

A

Trastuzumab

43
Q

Hyperaldosteronism

A

Spironolactone

44
Q

Honeycomb womb

A

Hydatidiform mole

45
Q

Side effect of tamoxifen

A

Endometrial hyperplasia, thromboembolli

46
Q

SE of trastuzumab

A

Cardiotox