Final- NS fundamentals Flashcards
Sensory (afferent)
- Transmits impulses from sensory receptors toward CNS
- Somatic-impulses from skin, skeletal muscles (conscious)
- Visceral-impulses from visceral organs toward CNS (unconscious)
Motor (efferent)
- transmits impulses away from CNS to effector organs
- somatic-impulses from CNS to skeletal muscles (conscious)
- autonomic-impulses from CNS to smooth muscle, cardiac muscle and glands (unconscious)
Difference between nuclei and ganglia
Nuclei-cluster of cell bodies in the CNS
Ganglia-cluster of cell bodies in the PNS
Anterograde transport
- moves substances away from cell body
- ex: neurotransmitters
Retrograde transport
- moves substances towards cell bodies
- ex: vesicles, NT recycling
What is MS made of and what is its purpose
- made of lipids from Schwann cells (PNS) and oligodendrocytes (CNS)
- purpose is the insulate axons and make AP faster
Depolarization
Makes the cell membrane more positive
Hyper polarization
Making the cell slightly more positive back to the RMP which is -55
Repolarization
Makes the cell negative down to -70
How do action potentials self propagate
Positive Na+ ions at origin activate neighboring VG Na+ channels
Saltatory conduction
Only generated at Nodes of Ranvier
Diffusion of Na+ ions under myelinated nerve segments cause a fast propagation of the AP stimulus in those regions
How can AP be blocked
- Novacain
- cold and pressure
Chemical synapse characteristics
- release and receptor of chemical NT
- slower than electrical
Electrical synapse
- least common
- neurons joined by gap junctions
- fast communication
- allow synchronization of interconnected neurons
Steps of chemical synapse transmission
- AP arrives at axon terminal
- VC Ca channels open, Ca rushes in
- Ca entry causes synaptic vesicles to release NT by exocytosis
- NT binds receptor on post synaptic neuron
- NT fate
- stays in synapse
- taken up by transport proteins
- enzymatically degraded
- diffused away from synapse