Final Exam - Notes: pages 13-19 Flashcards
Disease: _________: disease of the gastrointestinal system
Etiology: Vibrio cholerae
Cholera
Disease: Cholera: disease of the _________ system
Etiology: Vibrio cholerae
gastrointestinal
Disease: Cholera: disease of the gastrointestinal system
Etiology: _________ cholerae
Vibrio
-Disease: _________ -
produces enterotoxin called choleragen which causes the body to lose water and electrolytes
Cholera
-Disease: Cholera-
produces enterotoxin called _________ which causes the body to lose water and _________
- choleragen
- electrolytes
-Disease: Cholera-
toxin is heat _________ - (heat can _________ the toxin)
- labile
- inactivate
-Disease: _________ -
Reservoir:
Nonliving (saltwater, freshwater)
Some humans are carriers (enteric)
Cholera
-Disease: Cholera-
Reservoir:
_________ (saltwater, freshwater)
Some humans are _________ (enteric)
- Nonliving
- carriers
-Disease: _________ -
Mode of Transmission: fecal-oral
- foodborne; in America eating raw shellfish
- waterborne
Cholera
-Disease: Cholera-
Mode of Transmission: _________
- foodborne; in America eating raw shellfish
- _________
- fecal-oral
- waterborne
-Disease: _________ -
Prodromal: vomiting, cramps, diarrhea
Invasion: rice water stool
Cholera
-Disease: Cholera-
_________ : vomiting, cramps, diarrhea
Invasion: _________ water stool
- Prodromal
- rice
-Disease: _________ -
High mortality rate due to massive loss of fluid and electrolytes
Cholera
-Disease: _________ -
Treatment:
- I.V. fluid and electrolyte replacement reduces mortality
- Antibiotics
Cholera
-Disease: Cholera-
Treatment:
- I.V. fluid and _________ replacement reduces mortality
- _________
- electrolyte
- Antibiotics
-Disease: Cholera-
Prevention:
_________ food
Boil water
_________
- Cook
- Vaccine
-Disease: Cholera-
Miscellaneous:
There have been 7 _________ of this disease since the early 1800’s
Currently there is an epidemic in _________
- pandemics
- Haiti
Disease: _________ : Legionnaires’ disease
Etiology: Legionella pneumophila
Legionellosis
Disease: Legionellosis: _________’ disease
Etiology: Legionella pneumophila
Legionnaires
Disease: Legionellosis: Legionnaires’ disease
Etiology: Legionella _________
pneumophila
-Disease: Legionellosis-
Reservoir: _________
Nonliving: water
-Disease: _________ -
Reservoir:
Nonliving: water
-The microbe is avirulent in natural bodies of water
-The microbe becomes virulent in hot water
Legionellosis
-Disease: Legionellosis-
Reservoir:
Nonliving: water
-The microbe is _________ in natural bodies of water
-The microbe becomes _________ in hot water
- avirulent
- virulent
-Disease: _________ -
Mode of Transmission:
- Airborne aerosols from cooling towers, showers, faucets, hot tubs etc.
- No known human to human transmission–noncommunicable
Legionellosis
-Disease: Legionellosis-
Mode of Transmission:
- Airborne _________ from cooling towers, showers, faucets, hot tubs etc.
- No known human to human transmission– _________
- aerosols
- noncommunicable
-Disease: Legionellosis-
Signs & Symptoms: Usually causes a _________ infection unless the person is compromised
subclinical
-Disease: Legionellosis-
_________ –Fever, chills, muscle aches, headache, fatigue, diarrhea—misdiagnosed as influenza
Prodromal
-Disease: Legionellosis-
_________ –renal failure chest x-rays often show pneumonia
Invasion
-Disease: Legionellosis-
Prodromal–Fever, _________, muscle aches, headache, fatigue, diarrhea—misdiagnosed as _________
- chills
- influenza
-Disease: Legionellosis-
Invasion– _________ failure chest x-rays often show _________
- renal
- pneumonia
-Disease: Legionellosis-
Legionnaires’ _________ cannot be distinguished from other types of pneumonia from _________ alone.
- pneumonia
- signs/symptoms
-Disease: Legionellosis-
Treatment: _________ : must be specific for _________’ disease
- Antibiotics
- Legionnaires
-Disease: Legionellosis-
Prevention:
-Test and _________ systems with disinfectants ( _________ )
- water
- Hyperchlorination
-Disease: _________ -
Prevention:
-Test and treat water systems with disinfectants (Hyperchlorination)
Legionellosis
-Disease: Legionellosis-
Prevention:
To prevent _________ (hospital related) Legionnaire’s disease, the CDC recommends that hospitals test and treat their water systems only _________ there have been 1 one or two cases of the disease.
- nosocomial
- after
-Disease: Legionellosis-
Risk factors (predisposing factors)
- _________
- > 65 years old
- _________ smoking
- Immunocompromised
- Male
- Cigarette
-Disease: Legionellosis-
Risk factors (predisposing factors)
- _________ abuse
- Organ transplantation (because they are given immunosuppressant drugs)
- _________
- Cancer
- Alcohol
- Emphysema
-Disease: Legionellosis-
Most outbreaks occur during the _________ due to air conditioning systems
-summertime
-Disease: Legionellosis-
_________ : This disease is a result of infection with Legionella with flu like signs/symptoms, but the disease does not progress to pneumonia. Usually misdiagnosed as Influenza.
-Most cases occur in the summertime
Pontiac fever
-Disease: Legionellosis-
Pontiac fever: This disease is a result of infection with Legionella with _________ signs/symptoms, but the disease does not progress to pneumonia. Usually misdiagnosed as _________.
-Most cases occur in the summertime
- flu like
- Influenza
Disease: _________
Etiology: E. coli O157:H7
Hemolytic Uremic Syndrome
Disease: Hemolytic Uremic Syndrome
Etiology: _________ O157:H7
E. coli
-Disease: Hemolytic Uremic Syndrome-
Produces an exotoxin called the _________
Shiga toxin
-Disease: Hemolytic Uremic Syndrome-
Reservoir: _________
Cows
-Disease: Hemolytic Uremic Syndrome-
Mode of Transmission: _________
foodborne
-Disease: Hemolytic Uremic Syndrome-
Mode of Transmission: foodborne
-Foods implicated in past outbreaks include: ground beef, _________ milk, unpasteurized juice, _________ sprouts, lettuce, spinach, _________
- unpasteurized
- alfalfa
- tomatoes
-Disease: _________ -
Signs & Symptoms:
most often severe bloody diarrhea and abdominal cramps
Hemolytic Uremic Syndrome
-Disease: Hemolytic Uremic Syndrome-
Signs & Symptoms:
most often severe bloody _________ and abdominal _________
- diarrhea
- cramps
-Disease: Hemolytic Uremic Syndrome-
Signs & Symptoms:
children under 5, _________, and the elderly progress to _________ uremic syndrome
–red blood cells are destroyed and kidneys fail
- immunocompromised
- Hemolytic
-Disease: Hemolytic Uremic Syndrome-
Signs & Symptoms:
children under 5, immunocompromised, and the elderly progress to
Hemolytic uremic syndrome
– _________ blood cells are destroyed and _________ fail
- red
- kidneys
-Disease: Hemolytic Uremic Syndrome-
Treatment:
- For HUS _________ and blood transfusions are needed
- _________, Fluids
- dialysis
- Antibiotics
-Disease: Hemolytic Uremic Syndrome-
Prevention:
- Cook meat especially _________ well-done (steak is not high risk)
- Avoid _________ when preparing food
- Drink only _________ milk, juice or cider
- hamburger
- cross-contamination
- pasteurized
-Disease: Hemolytic Uremic Syndrome-
Prevention:
- _________ fruit and vegetables thoroughly
- _________ recommends that children
- Wash
- CDC
- alfalfa sprouts
-Disease: _________ -
Sequeale (after effects) of HUS include seizures, blindness, deafness, chronic kidney failure, neurological impairment
Hemolytic Uremic Syndrome
-Disease: Hemolytic Uremic Syndrome-
Sequeale (after effects) of HUS include seizures, blindness, _________, chronic kidney failure, _________ impairment
- deafness
- neurological
Disease: _________
Etiology: Salmonella typhimurium
Salmonella enteritidis
Salmonellosis
Disease: Salmonellosis
Etiology: Salmonella _________
Salmonella _________
- typhimurium
- enteritidis
-Disease: Salmonellosis-
Reservoir: _________ –Enteric
Animal
-Disease: _________ -
Reservoir: Animal–Enteric
- Poultry i.e. chicken, turkey, ducks
- Reptiles - Snakes, turtles, lizards
- Cows
- Pigs
Salmonellosis
-Disease: Salmonellosis-
Reservoir: Animal–Enteric
- Poultry i.e. chicken, turkey, ducks
- _________ - Snakes, turtles, lizards
- Cows
- _________
- Reptiles
- Pigs
-Disease: Salmonellosis-
Mode of Transmission:
- _________
- _________
- foodborne
- waterborne
-Disease: Salmonellosis-
Signs & Symptoms:
abdominal _________, fever, _________
- cramps
- diarrhea
-Disease: Salmonellosis-
Treatment:
- _________ Fluids.
- Antibiotics (many strains are drug _________)
- I.V.
- resistant
-Disease: Salmonellosis-
Prevention:
- Cook food
- Avoid _________
- Hand washing
- Don’t eat raw or undercooked eggs (found in yolk)
- Wash hands after handling _________
- cross-contamination
- reptiles
-Disease: _________ -
Sequelae:
A small number of infected people will go on to develop pain in their joints, irritation of the eyes,
and painful urination.
This is called Reiter’s syndrome.
It can last for months to years, and can lead to chronic arthritis
Salmonellosis
-Disease: Salmonellosis-
Sequelae:
A small number of infected people will go on to develop pain in their _________, irritation of the eyes,
and painful urination.
This is called _________ syndrome.
It can last for months to years, and can lead to chronic _________
- joints
- Reiter’s
- arthritis
-Disease: Salmonellosis-
Estimated incidence is over __ million with a mortality rate of _____/year
- 6
- 1000
Disease: _________
- Disease of the gastrointestinal tract
- Commonly misdiagnosed as Salmonellosis
Etiology: Campylobacter jejuni
Campylobacteriosis
Disease: Campylobacteriosis
- Disease of the _________ tract
- Commonly misdiagnosed as _________
Etiology: Campylobacter jejuni
- gastrointestinal
- Salmonellosis
Disease: Campylobacteriosis
- Disease of the gastrointestinal tract
- Commonly misdiagnosed as Salmonellosis
Etiology: Campylobacter _________
jejuni
-Disease: Campylobacteriosis-
Reservoir: _________ : especially _________ (one drop of juice from raw poultry can infect a person)
- Animal
- poultry
-Disease: Campylobacteriosis-
Mode of Transmission:
- _________
- _________
- foodborne
- waterborne
-Disease: Campylobacteriosis-
Signs & Symptoms:
-Most people get _________ (bloody), cramping, _________ pain, fever
- diarrhea
- abdominal
-Disease: Campylobacteriosis-
Treatment:
- I.V. _________
- _________
- fluids
- Antibiotics
-Disease: Campylobacteriosis-
Prevention:
- cook food
- _________ hands
- avoid cross contamination
- do not wash _________
- wash
- poultry
-Disease: Campylobacteriosis-
Sequelae:
- in rare cases people may have _________ following Campylobacteriosis
- others may develop _________-Barre syndrome (autoimmune disorder of the nervous system)
- arthritis
- Guillain
-Disease: _________ -
Sequelae:
- in rare cases people may have arthritis
- others may develop Guillain-Barre syndrome (autoimmune disorder of the nervous system)
Campylobacteriosis
Disease: _________ (Bacillary Dysentery)
-Dysentery is inflammation of the intestine resulting in diarrhea with blood
Etiology:
- Shigella sonnei (most cases in America are due to this species)
- Shigella flexneri
- Shigella dysenteriae type 1
Shigellosis
Disease: Shigellosis (_________)
-Dysentery is inflammation of the intestine resulting in diarrhea with blood
Etiology:
- Shigella sonnei (most cases in America are due to this species)
- Shigella flexneri
- Shigella dysenteriae type 1
Bacillary Dysentery
Disease: Shigellosis (Bacillary Dysentery)
-Dysentery is inflammation of the _________ resulting in _________ with blood
Etiology:
- Shigella sonnei (most cases in America are due to this species)
- Shigella flexneri
- Shigella dysenteriae type 1
- intestine
- diarrhea
Disease: Shigellosis (Bacillary Dysentery)
-Dysentery is inflammation of the intestine resulting in diarrhea with blood
Etiology:
- Shigella _________ (most cases in America are due to this species)
- Shigella flexneri
- Shigella dysenteriae type 1
sonnei
-Disease: _________ -
produces the Shiga toxin -Just like E. coli 0157:H7
Shigellosis
-Disease: Shigellosis-
Reservoir: _________
Human (enteric)
-Disease: Shigellosis-
Mode of Transmission:
- Direct or indirect _________ (bacteria passing from stools or soiled _________ of one person to the _________ of another person; fecal– oral)
- Vehicle (foodborne or waterborne)
- Mechanical vector - Flies
- contact
- fingers
- mouth
-Disease: Shigellosis-
Mode of Transmission:
- Direct or indirect contact (bacteria passing from stools or soiled fingers of one person to the mouth of another person; fecal– oral)
- _________ (foodborne or waterborne)
- _________ vector - Flies
- Vehicle
- Mechanical
-Disease: Shigellosis-
Signs & Symptoms:
- Diarrhea containing blood and _________ (dysentery)
- Fever
- _________
- mucus
- Cramp
-Disease: Shigellosis-
Treatment:
- I.V. Fluid and _________
- _________ (drug resistance is a concern with this microbe)
- electrolytes
- Antibiotics
-Disease: Shigellosis-
Prevention:
- Good basic _________ and hand-washing
- Cooking food
- _________ water
- hygiene
- Boiling
-Disease: Shigellosis-
Sequelae
% of persons who are infected get _________ syndrome (post infection arthritis)
Sometimes _________ syndrome occurs after infection with Shigella dysenteriae type 1 -because of the Shiga toxin
- Reiter’s
- Hemolytic uremic
-Disease: Shigellosis-
Sequelae
Approximately 2-3% of persons who are infected get Reiter’s syndrome (post infection _________)
Sometimes Hemolytic uremic syndrome occurs after infection with Shigella dysenteriae type 1 -because of the _________ toxin
- arthritis
- Shiga