Female Repro I

Question 1

What structures does the pelvic peritoneum cover?

Answer 1

the uterus, bladder, fallopian tubes, and rectosigmoid colon

Question 2

What are ‘powder burns’?

Answer 2

Suface affeted by endometriosis that has a brown discoloration which can fom cysts up to 15cm in diameter which containe chocolate cysts

Question 3

Where is clear cell carcinoma typically seen?

Answer 3

anterior wall of upper third of vagina. Clear cell is due to the abundant glycogen.

Question 4

How does a urethral caruncle present macro and microscopically?

Answer 4

Macro: mass 1-2cm near urethral meatus polypoid, inflammatoroyand ulcerated
Micro: Inflamed granulation tissue and ulceration and hyperplasio of transitional cell or squamous epithelium.

Question 5

What epithelium do serous epithelial tumor of the ovary resemble?

Answer 5

epithelium of the fallopian tubes

Question 6

What epithelium do mucinous epithelial tumor of the ovary resemble?

Answer 6

mucinous tumor hat mimic the mucosa of the endocervix

Question 7

what are the charactersitics of a Paget cell?

Answer 7

clear, vacuolated cytoplasm that contains glycosaminoglycans

Question 8

What autoimmunde diseases are associated with LIchen sclerosis?

Answer 8

Vitiligo, Perniocious anemia, and thyroiditis

Question 9

Histologically, how does lichen sclerosis present?

Answer 9

hyperkeratitis, absence of rete ridges, a homogeneous, accellular zone in the upper dermis

Question 10

The median time of the first detection of HPV is?

Answer 10

3 months

Question 11

What kind of cells are seen in HPV infection?

Answer 11

Vacuolated cells-koilocytes

Question 12

What organisms causes Lymphogranuloma enereum?

Answer 12

C. trachomatis

Question 13

What does Garnerella vaginalis cause?

Answer 13

nonspecific vaginitis

Question 14

What are the three stages of Lymphogranuloma venereum?

Answer 14

1. painelss vesicle at site of inoculation 2. b/l enlarged inguinal lymph nodes that may rupture and form suppurative fistulas
2. lymphatic obstruction that leads to genital elephantiasis and rectal strictures

Question 15

How do endometrial stromal sarcomas present microscopically?

Answer 15

They show a vascular supporting framework with neoplastic cells concentrically arranged around a blood vessel

Question 16

How does the core of an endometrial polyp appear microscopically?

Answer 16

endometrial gland (often cystic and dilated)
endometrial stroma (fibrous)
blood vessels (thick-walled, dilated, coiled)

Question 17

How does Adenomyosis appear microscopically?

Answer 17

Displaced endometrial glands (proliferative to inactive) and stroma (varying degrees of fibrosis) are located in the myometrium.

Question 18

Why are nulliparous women more at risk for surface epithelial tumors?

Answer 18

Research suggests that common epithelial neoplasms are related to repeated disruption and repair of the epithelial surface during normal cyclic ovulation. pregnant woman have had ovulation depressed.

Question 19

What are Call-Exner bodies?

Answer 19

microscopical granulosa cell tumors that display haphazard orientation oft he nuclei about a central degenerative space.

Question 20

Describe the appearance of Dysgerminomas

Answer 20

Uniform cell types with clear glycogen-filled cytoplasm and irregularly flattened central nuclei. They resemble oocytes. Fibrous septa traverse the tumor.

Question 21

Dysgerminoma is analogous to what male tumor?

Answer 21

Seminoma

Question 22

What is the most common vulvar neoplasm that VIN is the origin of?

Answer 22

squamous cell carcinoma of the vulva

Question 23

Which nodes do the sq. cell carcinoma of vulva metastasize to? body regions?

Answer 23

superficial then deep inguinal nodes, pelvic nodes, femoral nodes

skin ,vagina, rectum

Question 24

What organs would be first be affected by choriocarcinoma metastasis?

Answer 24

Lungs and Brain

Question 25

What does abrupto placentiae refer to?

Answer 25

retroplacental hemorrhage in absence of clinical hemmorrhage

Question 26

What are the most common infectious agents associated with Bartholin gland cysts?

Answer 26

It was fomerly associated with gonorrhea but now staphylococci, chlamydia, and anareobes are more frequently the cause

Question 27

What disease is associated with Toxic Shock Syndrome?

Answer 27

DIC

Question 28

What does the stroma of the ovarian cortex consist of?

Answer 28

well-differentiated Fibroblasts and varied amounts of collagen

Question 29

How do thecomas appear microscopically?

Answer 29

They are yellow in a cut section because of lipid-laden theca cells. The cells are large, and oblong to round, with a vacuolated cytoplasm that contains lipid. Bands of hyalinized collagen separate nests of theca cells

Question 30

What kind of tumors secrete estrogen in females?

Answer 30

Sex- Cord

Question 31

Why is obesity associated with more estrogen?

Answer 31

There is enhanced aromatization of androstenedione to estrone in adipocytes.

Question 32

Haemophilus ducreyi causes what?

Answer 32

Chancroid: which can produce erythematous papules of the external genitalia or vagina, bu grosslyvisible lesions may not be present.

Question 33

Describe extra mammary Paget Disease presentation

Answer 33

red scaling, adenocarcinoma-like cells at the dermal lepidermal junction.