Female Repro I Flashcards
What structures does the pelvic peritoneum cover?
the uterus, bladder, fallopian tubes, and rectosigmoid colon
What are ‘powder burns’?
Suface affeted by endometriosis that has a brown discoloration which can fom cysts up to 15cm in diameter which containe chocolate cysts
Where is clear cell carcinoma typically seen?
anterior wall of upper third of vagina. Clear cell is due to the abundant glycogen.
How does a urethral caruncle present macro and microscopically?
Macro: mass 1-2cm near urethral meatus polypoid, inflammatoroyand ulcerated
Micro: Inflamed granulation tissue and ulceration and hyperplasio of transitional cell or squamous epithelium.
What epithelium do serous epithelial tumor of the ovary resemble?
epithelium of the fallopian tubes
What epithelium do mucinous epithelial tumor of the ovary resemble?
mucinous tumor hat mimic the mucosa of the endocervix
what are the charactersitics of a Paget cell?
clear, vacuolated cytoplasm that contains glycosaminoglycans
What autoimmunde diseases are associated with LIchen sclerosis?
Vitiligo, Perniocious anemia, and thyroiditis
Histologically, how does lichen sclerosis present?
hyperkeratitis, absence of rete ridges, a homogeneous, accellular zone in the upper dermis
The median time of the first detection of HPV is?
3 months
What kind of cells are seen in HPV infection?
Vacuolated cells-koilocytes
What organisms causes Lymphogranuloma enereum?
C. trachomatis
What does Garnerella vaginalis cause?
nonspecific vaginitis
What are the three stages of Lymphogranuloma venereum?
- painelss vesicle at site of inoculation 2. b/l enlarged inguinal lymph nodes that may rupture and form suppurative fistulas
- lymphatic obstruction that leads to genital elephantiasis and rectal strictures
How do endometrial stromal sarcomas present microscopically?
They show a vascular supporting framework with neoplastic cells concentrically arranged around a blood vessel
How does the core of an endometrial polyp appear microscopically?
endometrial gland (often cystic and dilated) endometrial stroma (fibrous) blood vessels (thick-walled, dilated, coiled)
How does Adenomyosis appear microscopically?
Displaced endometrial glands (proliferative to inactive) and stroma (varying degrees of fibrosis) are located in the myometrium.
Why are nulliparous women more at risk for surface epithelial tumors?
Research suggests that common epithelial neoplasms are related to repeated disruption and repair of the epithelial surface during normal cyclic ovulation. pregnant woman have had ovulation depressed.
What are Call-Exner bodies?
microscopical granulosa cell tumors that display haphazard orientation oft he nuclei about a central degenerative space.
Describe the appearance of Dysgerminomas
Uniform cell types with clear glycogen-filled cytoplasm and irregularly flattened central nuclei. They resemble oocytes. Fibrous septa traverse the tumor.
Dysgerminoma is analogous to what male tumor?
Seminoma
What is the most common vulvar neoplasm that VIN is the origin of?
squamous cell carcinoma of the vulva
Which nodes do the sq. cell carcinoma of vulva metastasize to? body regions?
superficial then deep inguinal nodes, pelvic nodes, femoral nodes
skin ,vagina, rectum
What organs would be first be affected by choriocarcinoma metastasis?
Lungs and Brain
What does abrupto placentiae refer to?
retroplacental hemorrhage in absence of clinical hemmorrhage
What are the most common infectious agents associated with Bartholin gland cysts?
It was fomerly associated with gonorrhea but now staphylococci, chlamydia, and anareobes are more frequently the cause
What disease is associated with Toxic Shock Syndrome?
DIC
What does the stroma of the ovarian cortex consist of?
well-differentiated Fibroblasts and varied amounts of collagen
How do thecomas appear microscopically?
They are yellow in a cut section because of lipid-laden theca cells. The cells are large, and oblong to round, with a vacuolated cytoplasm that contains lipid. Bands of hyalinized collagen separate nests of theca cells
What kind of tumors secrete estrogen in females?
Sex- Cord
Why is obesity associated with more estrogen?
There is enhanced aromatization of androstenedione to estrone in adipocytes.
Haemophilus ducreyi causes what?
Chancroid: which can produce erythematous papules of the external genitalia or vagina, bu grosslyvisible lesions may not be present.
Describe extra mammary Paget Disease presentation
red scaling, adenocarcinoma-like cells at the dermal lepidermal junction.
