Fármacos para tratar enfermedades tiroideas Flashcards

1
Q

Hormona tiroidea que se encuentra en mayor cantidad pero tiene menor potencia:

A

Tetrayodotironina (T4) - 93%

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2
Q

Hormona tiroidea que tiene mayor potencia pero de encuentra en menor cantidad:

A

Triyodotironina (T3) - 7%

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3
Q

Rango normal de TSH:

A

0.4 - 4.0 mIU/L

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4
Q

Rango normal de T4 total:

A

5.4 - 11.5 mcg/dL

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5
Q

Rango normal de T4 libre:

A

0.7 - 1.8 ng/dL

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6
Q

Rango normal de T3 total:

A

80 - 220 ng/dL

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7
Q

Rango normal de T3 libre:

A

260 - 480 pg/dL

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8
Q

¿Cuáles son las tioamidas?

A

Metimazol y Propiltiouracilo (PTU).

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9
Q

Mecanismo de acción de las tioamidas:

A

Inhiben a la tioperoxidasa, bloqueando la organificación del yodo.

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10
Q

Inhibe la conversión de T4 a T3 en los tejidos:

A

Propiltiouracilo (PTU).

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11
Q

Entra a la glándula tiroides y emite rayos β, destruyendo así el tejido:

A

Yodo radioactivo I-131.

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12
Q

Yodo radioactivo que se usa con fines diagnósticos:

A

I-123.

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13
Q

T4 sintética:

A

Levotiroxina

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14
Q

T3 sintética:

A

Liotironina

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15
Q

Preparados de hormonas tiroideas:

A

Levotiroxina (T4) y Liotironina (T3).

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16
Q

Mecanismo de acción del teprotumumab:

A

Inhibidor de IGF-IR y receptor del factor de crecimiento similar a la insulina 1 dentro de la órbita del ojo.
mAb anti-IGF-1R completamente humano.