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RUSVM Virology Summer 2017 > Family: Papillomaviridae > Flashcards

Family: Papillomaviridae Flashcards

1
Q

Which of the following is not a property of Papilomaviridae?
A. They can transform cultured cells
B. Produce papillomas (warts) on the skin and mucous membranes of most animal species
C. Are zoonotic
D. Warts are benign neoplasms typically
E. HPV causes cervical carcinoma in women and is an exception as it is malignant

A

C. Are zoonotic

–THEY ARE USUALLY SPECIES AND HOST SPECIFIC!

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2
Q 
Replication of papilloma viruses is linked to the growth and differentiation of cells in \_\_\_\_\_\_ epithelium of the skin and some mucus membranes. 
A. squamous
B. stratified squamous
C. traditional 
D. keratinized stratified squamous
A

B. stratified squamous

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3
Q

T/F: In beings warts, the papilloma virus DNA is episomal, meaning it is not integrated into the host- cell DNA and persist as an autonomously replicating episome. In malignant papilloma virus cancers the viral DNA is integrated into the host cell.

A

True!

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4
Q 
Which is not apart of papillomaviridae? 
A. Bovine Papillomatosis 
B. Canine Oral Papillomatosis 
C. Equine Sarcoids 
D. Porcine Oral papillomatosis
A

D. Porcine Oral papillomatosis

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5
Q

T/F: Natural bovien papilloma virus infection in horses may occur after exposure of the horses to cattle.

A

True!

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6
Q 
Which of the following is not a transmission route for Bovine Paillomatosis? 
A. contaminated fomites
B. contaminated equipment
C. Sexual transmission of venereal warts
D. Ticks
A

D. Ticks

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7
Q 
Which Bovine Papilloma virus type(s) causes Fibropapilloma? 
A. Type 1
B. Type 2
C. Type 3
D. Type 4
E. Type 5 
F. A, B and D
G. A, B and E
A

G. A, B and E

–1,2, and 5

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8
Q 
Which Bovine Papilloma virus type(s) causes Cutaneous Papillomas? 
A. Type 1
B. Type 2
C. Type 3
D. Type 4
E. Type 5 
F. A, B and D
G. A, B and E
A

C. Type 3

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9
Q 
Which Bovine Papilloma virus type(s) causes Bracken Fern and Papillomaviruses? 
A. Type 1
B. Type 2
C. Type 3
D. Type 4
E. Type 5 
F. A, B and D
G. A, B and E
A

F. A, B and D

  • -1,2 and 4
  • -type 4: can cause transient papillomas in the alimentary tract. Ingestion of the broken fern can result in transition to invasive carcinoma of the alimentary tract.
  • -If cattle eat bracken fern, type 1 and 2 may also contribute to the syndrome of “enzootic hematuria” that is characterized by hematuria and/ or bladder cancer.
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10
Q 
Which Bovine Papilloma virus type(s) causes transient papillomas in the alimentary tract in Bracken Fern and Papillomaviruses?( note: Ingestion of the broken fern can result in transition to invasive carcinoma of the alimentary tract)
A. Type 1
B. Type 2
C. Type 3
D. Type 4
E. Type 5 
F. A, B and D
G. A, B and E
A

D. Type 4

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11
Q 
Which Bovine Papilloma virus type(s) may contribute to the syndrome of "enzootic hematuria" that is characterized by hematuria and/ or bladder cancer (in broken fern and papillomaviruses)? 
A. Type 1
B. Type 2
C. Type 3
D. Type 4
E. Type 5 
F. A, B 
G. A, B and E
A

F. A, B

–type 1 and 2

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12
Q

Papillomas thar have a fibrous core covered with stratified squamous epithelium, outer layers which are hyperkeratinized; lesions with small firm nodules to large cauliflower- growth; Grayish to back in color- in Bovine Papillomatosis are considered to be:
A. Cutaneous Papillomas
B. Fibropapilloma
C. Bracken Fern and aPapillomaviruses

A

B. Fibropapilloma

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13
Q

Papillomas without a fibrous core that are usually flat with a broad base and are often pedunculate in -Bovine Papillomatosis are considered to be:
A. Cutaneous Papillomas
B. Fibropapilloma
C. Bracken Fern and aPapillomaviruses

A

A. Cutaneous Papillomas

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14
Q

T/F: Fibropapillomas lack a fibrous core and Cutaneous papillomas have a covered fibrous core (In bovine papillomatosis).

A

FALSE!!!

  • -it is reversed!
  • -Cutaneous papillomas lack a fibrous core and Fibropapillomas have a covered fibrous core
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15
Q

Which of the following is/ are treatment option(s) for Bovine Papillomatosis?
A. Bovin interferon- alpha
B. Topical agents (DMSO)
C. Surgical excision or cryosurgery with liquid nitrogen
D. All of the above

A

D. All of the above

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16
Q

It there a vaccine for Bovine Papilloma virus?

A

Yes! it is a wart vaccine

17
Q

T/F: Fibropapillomas are common on the udder, teats, head neck and shoulder and may also occur in the omasum, vagina, vulva, penis, and anus.

A

True!

18
Q

Which of the following is not true in regards to Canine Oral Papillomatosis?
A. The warts are usually begin on the lips, and can spread to the mucosa, tongue, palate and pharynx. The may become roughed and cauliflower-like but they do not extend below the epiglottis or into the esophagus.
B. Lesions typically regress spontaneously
C. Progression to squamous cell carcinoma occurs very rarely
D. All of the above are true

A

D. All of the above are true

19
Q

Which of the following are clinical signs of Canine Oral papillomatosis?
A. Halitosis (bad breath), hemorrhage, ptyalism (hyper salivation, discomfort.
B. Numerous warts may interfere with mastication and deglutition
C. Warts may regress or secondary bacterial infection and ulceration may occur
D. Ocular warts may appear in the conjunctiva, cornea, and eyelid margins
E. Recovered dogs are refractory (resistant) to reinfection.
F. All of the above are clinical signs

A

F. All of the above are clinical signs

20
Q

What treatment can be done for Canine Oral Papillomatosis?
A. Surgical excision
B. Cryosurgery
C. Electrosurgery
D. Autogenous Vaccines may be tried but efficacy is doubtful
E. All of the above

A

E. All of the above

21
Q

Which of the following is not true in regards to Equine Sarcoids?
A. Commonly in horses, donkeys and mules between 1-6 years old and is the most common neoplasm in horses.
B. They are locally invasive malignant fibroblasts skin tumors
C. Associated with Bovine papillomaviruses 1 and 2
D. Sacroids do not metastasize. They may persist for life, are locally invasive and recur after surgical removal

A

B. They are locally invasive malignant fibroblasts skin tumors
–They are locally invasive BENIGN fibroblasts skin tumors

22
Q

T/F: Lesions in equine scrods commonly occur in traumatized areas, can be single or multiple. Growths may reach the size of a main’s fist and bulge under the skin. Lesions may become ulcerated.

A

True!

23
Q 
Which of the following is appropriate method of treatment in equine sarcoids? 
A. Cryotherapy
B. Surgical of laser excision
C. Local immune modulation
D. Local radiotherapy
E. All of the above
A

E. All of the above

RUSVM Virology Summer 2017 (23 decks)

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