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RUSVM Virology Summer 2017 > Family: Asfarviridae > Flashcards

Family: Asfarviridae Flashcards

1
Q 
Which of the following virus(s) is in family Asfarviridae?
A. Feline Panleukopenia
B. African Swine Fever 
C. Canine Parvovirus 1
D. Porcine Parvovirus
A

B. African Swine Fever

–The Sole member of Family Asfarviridae

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2
Q 
Which virus is the ONLY known DNA Arbovirus?
A. Swine pox
B. FPV
C. African Swine Fever
D. African Cattle Fever
A

C. African Swine Fever

–there is not african cattle fever in this family

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3
Q 
What is the host of African Swine Fever?
A. Cattle
B. Only Domestic Swine 
C. Domestic swine and european wild boar
D. Inapparent infection in warthogs, bush pigs, and giant forest hogs, which act as reservoirs
E. both C and D
A

E. both C and D

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4
Q 
African Swine Fever is an
A. OIE List A disease
B. OIE List B disease
C. OIE list C disease 
D. OIE list D disease
A

A. OIE List A disease

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5
Q 
Where is African Swine Fever Endemic? 
A. Most of sub-Saharan Africa 
B. Eastern Russia
C. Island of Sardinia (Italy)
D. Eastern Europe 
E. Both A and C
F. Both B and D 
G. A, C and D 
H. All of the above
A

E. Both A and C

–most of sub-Saharan Africa and Island of Sardinia (Italy)

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6
Q 
Where was there a recent outbreak of African Swine Fever? 
A. Most of sub-Saharan Africa 
B. Eastern Russia
C. Island of Sardinia (Italy)
D. Eastern Europe 
E. Both A and C
F. Both B and D 
G. A, C and D 
H. All of the above
A

F. Both B and D

–Eastern Russia and Europe

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7
Q

Which of the follow is incorrect reading the Stability of African swine fever virus?
A. It can survive in chilled carcasses for up to 6 months
B. Virus and survive at least 30 days in pens
C. It is very resistant to a wide range of pH and to putrefaction.
D. It doesn’t remain viable for long in blood, feces and tissues - especially not in undercooked pork products
E. Can multiply in vectors

A

D. It doesn’t remain viable for long in blood, feces and tissues - especially not in undercooked pork products
–IT REMAINS VIABLE for long periods of time in blood, feces and tissues- especially infected, uncooked or undercooked pork products!

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8
Q 
What is the specific vector for African swine fever in africa? 
A. Ornithodorus moubata 
B. Hard ticks
C. flies 
D. Ornithodorus erraticus
A

A. Ornithodorus moubata

  • -It is a soft tick
  • -O. erraticus is the tick in Spain and Portugal
  • -Ornithodorus sp. is the biological vectors of the virus; Virus replicates in the tick and is can be sexually transmitted from tick to tick. Infected ticks may live for several years and are capable of transmitting virus to pigs during each blood meal
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9
Q 
Which of the following is/are the reservoir host(s) for African swine fever sylvatic cycle?
A. Domestic Swine
B. Warthog
C. Giant Forest Hog
D. Brush pig
E. B-D
F. All of the above
A

E. B-D

–remember that sylvatic cycle means occurring in or infecting “wild” animals! So not domestic swine!

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10
Q

Which of the following is not true about the Sylvatic cycle of African Swine Fever (ASF)?
A. Sylvatic cycle is the transmission of ASF between warthog and soft ticks
B. ASF is mainainted in a sylvatic cycle
C. Young and old wild pigs develop viremia
D. Virus titers can get high enough in pigs to infect ticks feeding on them
E. all of the above are true

A

C. Young and old wild pigs develop viremia

–Young wild pigs develop viremia; Older wild pigs are persistently infected, but rarely develop viremia!

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11
Q

Which of the following is not true about transmission of the Domestic Cycle of African Swine Fever?
A. This is where primary outbreaks occur!
B. Bite of an infected tick
C. Direct contact with infected animal via oronasal spread
D. Indirect contact on fomites
E. Virus can spread by feeding domestic pigs uncool scraps that contain pork
F. Aerosol spread
G. Mechanical transmission through biting flies
H. All of the above are true

A

H. All of the above are true

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12
Q

T/F: In the domestic cycle of African Swine Fever all body fluids and tissues contain large amounts of infectious virus when infected and pigs can become carriers and shed the virus if they survive infection.

A

True!

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13
Q 
What are the primary effects (pathogenesis) of ASF?
A. Hemorrhages
B. Apoptosis 
C. Abortion
D. Both A and B
E. All of the above
A

D. Both A and B

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14
Q

T/F: Leukopenia, Lymphopenia, and Thrombocytopenia are also associated ASF pathogenesis.

A

True!

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15
Q

Which of the following is true in regards to Apoptosis of host cells due to the pathogenesis of ASF?
A. P54 protein (encoded by virus) directly induces apoptosis of host cells
B. Apoptosis of both lymphocytes and monocular phagocytic cells
C. AST infected macrophages release cytokines and apoptotic mediators
D. All of the above are true

A

D. All of the above are true

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16
Q 
Which of the following is not a mechanism due to thrombocytopenia and coagulation defects caused by ASF?
A. Edema
B. Infarction
C. Exudation 
D. Hemorrhages
E. Abortion
A

E. Abortion

17
Q

Which of the following is not true in regards to mechanisms related to hemorrhages due to ASF?
A. Vascular damage from degeneration of vascular endothelium
B. DIC (Disseminated intravascular coagulation
C. Abortion
D. Infection and necrosis of megakaryocytic resulting in Thrombocytopenia
E. Activation and extensive destruction of monocytes and macrophages
F. All are true

A

C. Abortion
– it is not specifically noted under mechanisms related to hemorrhages, however in the acute form abortion is sometimes the first event seen in an outbreak!

18
Q 
Which of the following forms of ASF results in a pig that may die suddenly?
A. Acute form
B. Peracute form 
C. Chronic form 
D. Subacute form
A

B. Peracute form

–there is not subacute form

19
Q 
Which of the following forms of ASF results in cyanotic skin blotching on the ears, tail, lower legs or hams? 
A. Acute form
B. Peracute form 
C. Chronic form 
D. Subacute form
A

A. Acute form

–KNOW THIS WELL, HE NOTED IT WAS VERY IMPORTANT!

20
Q 
Which of the following forms of ASF can result in high fever, respiratory distress, diarrhea, abortion and death? 
A. Acute form
B. Peracute form 
C. Chronic form 
D. Subacute form
A

A. Acute form

21
Q 
Which of the following forms of ASF can result in an enlarged friable spleen (Blackberry Jam Spleen)?
A. Acute form
B. Peracute form 
C. Chronic form 
D. Subacute form
A

C. Chronic form

–KNOW THIS WELL, HE NOTED IT WAS VERY IMPORTANT!

22
Q 
Which of the following forms of ASF can result in emaciation, swollen joints, Ulcers and reddened or raised necrotic skin foci, Pneumonia, Cutaneous lesions snd fibrous pericarditis and myocardial hemorrhage? 
A. Acute form
B. Peracute form 
C. Chronic form 
D. Subacute form
A

C. Chronic form

23
Q

T/F: infected pigs produce virus specific antibodies against ASF but humoral immunity response does not seem to have substantial protective value.

A

True!!

–This is because the sera form infected pigs do not neutralize the virus

24
Q

Is there a vaccine for ASF?

A

NO!! attempts to develop a vaccine have been unsuccessful so far

25
Q

How can one prevent ASF?
A. Be albe to recognize and suspect if swine have ASF, specially pig farmer and field personnel
B. Pigs should be in well- contracted pig sties under hygienic conditions
C. control movement of pigs inside the country and especially across international borders
D. Pigs should not be fed swill that might contain remains of pigs
E. All of the above are acceptable preventive measures against ASF

A

E. All of the above are acceptable preventive measures against ASF

26
Q

Is African Swine Fever Reportable?

A

YES!!!!

–IMMEDIATELY NOTIFY AUTHORITIES (ANIMAL HEALTH DEPARTMENT)!

27
Q

During an outbreak one should…
A. place suspected farms under quarantine
B. Not move pigs or products of pig origin
C. Slaughter all infected pigs
D. Burn carcasses of or bury them deep on site
E. Vehicles and personal apparel (shoes, clothes) and equipment should be disinfected on entering and leaving farms!
F. All of the above should be done during an outbreak

A

F. All of the above should be done during an outbreak

RUSVM Virology Summer 2017 (23 decks)

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