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Reproductive > Exam 3 part 3 > Flashcards

Exam 3 part 3 Flashcards

1
Q

are defined as any drug, viruses, infections, or other exposures that can cause embryonic and or fetal development abnormality

A

teratogens

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2
Q

Degree ant type of malformation depends on

A

Length of exposure
Amount of exposure
When it occurs during human development

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3
Q

ionizing radiation cause most damage to the

A

central nervous system

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4
Q

ionizing radiation can cause

A

Mental retardation
Microcephaly
IUGR

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5
Q

deficiency of vitamin A can lead to

A

eye
cleft lip
facial defects

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6
Q

deficiency of vitamin B can lead to

A

neural tube defects

Infantile seizures

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7
Q

deficiency of vitamin C can lead to

A

neural tube defects

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8
Q

deficiency of vitamin D can lead to

A

Reduced fetal growth
Neonatal hypocalcemia
Neonatal rickets
defective tooth enamel

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9
Q

maternal diabetes can lead to fetal

A

IUGR

Cardiac defects

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10
Q

folic acid metabolic abnormalities can lead to fetal

A

neural tube defects

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11
Q

maternal hyperthermia can lead to fetal

A

Neural tube defects

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12
Q

maternal hypo and hyperthyroidism can lead to fetal

A

Heart
Kidney
CNS

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13
Q

chorionic villus sampling (CVS) usually done before day 70 can cause

A

limb anomalies

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14
Q

medication class that has controlled studies that show no risk Ex: folic acid

A

category A

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15
Q

medication class that has studies in animals or humans that show fetal abnormalities or there is evidence of fetal risk based on human use and the risk clearly outweighs and benefit Ex: Isotretinoin (Acutain)

A

category X

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16
Q

medication class that has animal studies that do not show risk but there are no human studies or animal studies show adverse effects but this is not confirmed in human studies Ex: amoxicillin and augmentin

A

category B

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17
Q

medication class that has animal studies that show risk and there are no human studies or there are no human or animal studies Ex: Rifamoicin

A

category C

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18
Q

medication class that has positive evidence of human fetal risk but benefits for some women outweigh the risk Ex: phenytoin and ACE inhibitors

A

category D

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19
Q

side effects of marijuana use in pregnancy

A

Stimulate uterine contractions
Shortened gestation (dose dependent)
IUGR
Neurobehavioral effects

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20
Q

Effects of cocaine on pregnancy

A

Increased risk for miscarriage early in pregnancy
May trigger preterm labor
IUGR
Increased risk for placental abruption

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21
Q

effects of cocaine on newborn

A

Increased irritability
increased startle reflex
difficulty with habituation
Difficult to console

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22
Q

heroin pregnancy effects

A 
Preterm labor
PROM
PIH
Placental abnormalities
Stillbirth
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23
Q

fetal effects of heroin

A

Increased fetal lung maturity
meconium stained amniotic fluid
respiratory problem after birth
Withdrawal with possible seizures

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24
Q

drug prescribed to block withdrawal symptoms and cravings

A

methadone

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25
Q

maternal effects of amphetamines

A 
Abruption 
PTL
Cardiac arrhythmia 
Poor appetite
Insomnia
26
Q

fetus effects of amphetamines

A

IUGR

Reduced brain growth

27
Q

newborn effects of ampthetamines

A

Withdrawal
Congenital heart defects
Increased clubfoot (in females)
Increased cleft lip and palate

28
Q

used for alcohol assessment

A

CAGE

29
Q

when can moms use barbiturates for withdrawal from alcohol

A

after first trimester

30
Q

Facial appearance in FAS

A

Microcephaly
Flat maxillary area
Flat philtrum
Thin upper lip

31
Q

women who smoke have increased risk of

A 
Miscarriage
Stillbirth
Placenta previa
Placental abruption
PROM
PTL and preterm birth
32
Q

a gene that is always expressed even if only one copy is present

A

autosomal dominant

33
Q

two copies of a defective gene must be present for it to be expressed

A

autosomal recessive

34
Q

examples of autosomal dominant disorders

A

Huntington’s

Achondroplasia

35
Q

examples of autosomal recessive disorders

A

Sickle cell
Tay sachs
Cystic fibrosis
Thalassemia

36
Q

males only inherit these from their fathers

Most rare type of disorder

A

Y-linked disorders

37
Q

Male or female child can express this
Father who carry can give it to daughters
Mothers can affect both genders

A

x linked dominate

38
Q

Both mother and father must give via the X chromosome for girls to express
Sons can only express if only mother is affected
If only father affected daughters will carry his X

A

x linked recessive

39
Q

Examples of x linked recessive

A

Color blindness
Hemophilia
Duchenes muscular dystrophy

40
Q

male congenital anomalies

A 
Cleft lip alone
Hypospadiasis
Clubfoot
Hirschprung disease
diaphragmatic hernia 
Pyloric stenosis
Congenital heart defects
41
Q

female congenital anomalies

A 
Congenital hip dislocation
Anencephaly 
Spina bifida
Pyloric stenosis
Congenital heart defects
42
Q

Lip alone or with palate seen primarily in

A

males

43
Q

palate alone seen more in

A

females

44
Q

shoulder dystocia can lead to

A

palsy
fracture
neurological trauma

45
Q

TORCH stands for

A 
Toxoplasmosis
Other (T.plallidum, VZV, parvovitus, hepatitis)
Rubella virus
Cytomegalvoirus (CMV)
Herpes simplex virus
46
Q

chorioretinitis can lead to what

A

color blindness

47
Q

neonate complications from toxoplasmosis are

A

hydrocephalus

intracranial calcification

48
Q

when is the greatest risk for congenital varicella

A

first 20 weeks

49
Q

mother with VZV after 20 weeks but before 110 days prior to delivery are treated symptomatically and given

A

acyclovir

50
Q

if the mother has VZV prior to 20 weeks the fetus can develop

A

congenital varicella syndrome

51
Q

treat infants with VZV with

A

VZIG

52
Q

CVS is associated with

A 
Cataracts 
Chorioretinitis
limb hypoplasia
mental retardation
dermatone lesions
cutaneous scars
53
Q

if maternal rubella contracted prior to 8 weeks there is a chance of

A

congenital rubella syndrome

54
Q

congenital rubella syndrome causes

A 
Cataracts
Cardiac defects
Deafness
Glaucome
Microcephaly
CNS defects
55
Q

S and S of babies born with CMV are

A 
Hearing/vision loss
Mental disability
Lung problems
Spleen/liver bleeding problems
Growth problems
56
Q

fetal infection of listeriosis acquired through placenta is usually

A

fatal

57
Q

newborn infections acquired through exposure in the birth canal results in

A

meningitis

Encephalitis

58
Q

treatment of Listeriosis includes

A

antibiotics (penicillin, ampicillin, or erythromycin)

59
Q

is basically the inflammation of the liver resulting from infection by different viruses transmitted sexually
Mode of transmission can be non-sexual also

A

Hepatits

60
Q

Most common cause of acute hepatitis
Spread by oro-fecal route
Oral or anal sexual contact can predispose someone to it
Best prevention is hand washing

A

Hepatits A

61
Q

S and S of hepatitis A

A 
Anorexia
Low grade fever
N/V
upper abdominal pain
Jaundice
62
Q

can hep A vaccine be given during pregnancy

A

yes

Reproductive (19 decks)

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