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Micro Anatomy > Exam 3 Lymphatic System > Flashcards

Exam 3 Lymphatic System Flashcards

1
Q

What are the primary organs of the lymphatic system?

A
  1. Bone marrow
  2. Cloacal bursa/ bursa of fabricius
  3. Thymus
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2
Q

What are the secondary organs of the lymphatic system?

A
  1. Lymph nodes
  2. Spleen
  3. mucosal associated lymphoid tissue
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3
Q

What is the function of the lymphatic system?

A

to protext the body against pathogenic organisms and their products and to help in the removal and disposal of cells undergoing natural or induced degenerations

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4
Q

What are the 2 mechanisms of action of the lymphatic system?

A
  1. phagocytosis

2. production of immunologically competent cells

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5
Q

Where are fixed macrophages found?

A 
sinusoids of:
Liver
spleen
lymph node
Reticulum of bone marrow
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6
Q

Where are free macrophages found?

A

Blood
lung
serous cavities

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7
Q

Cells that capture, process and present protein fragments from extracellular antigens

A

APCs

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8
Q

What are the 3 APCs?

A
  1. Dendritic cells
  2. Macrophages
  3. B-cells
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9
Q

Where does T cell differentiation occur?

A

Thymus

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10
Q

Where does B cell differentiation occur?

A

bursa or bone marrow

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11
Q

What are the 2 types of stromal cells found in the lymphatic system?

A

Reticular and epithelial reticular cells

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12
Q

What is the cloacal bursa?

A

aka bursa of fabricus

dorsal wall of the cloaca, functionally equivalent to mammalian bone marrow for b cell differentiation

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13
Q

Where is the thymus located?

A

in the mediastinum just cranial to the heart

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14
Q

Which part of the thymus is the area of positive selection?

A

Cortex

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15
Q

Which part of the thymus is the area of negative selection?

A

Medulla

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16
Q

Large central calcified or degenrated cells surrounded by concentric circles of keratinized cells

A

Hassall’s corpuscles

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17
Q

What is the corticomedullary junction?

A

Area of the thymus where arteries enter

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18
Q

Organ that filters antigens from lymph before returning it to bloodstream

A

Lymph Nodes

19
Q

What is the only lymphatic organ with both afferent and efferent lymph vessels and sinuses containing lymph?

A

Lymph nodes

20
Q

The dense, irregular connective tissue of the lymph node

A

Capsule

21
Q

Extend from capsule into the cortex and medulla of lymph nodes

A

Trabeculae

22
Q

reticular cells and fibers that support lymphocytes, macrophages, and plasma cells, located in lymph nodes

A

Lymph node stroma

23
Q

Lymph vessels open into the _______

A

Subscapsular sinus

24
Q

Trace the path of lymph through the lymph node!

A

Afferent vessel– Marginal (subscapsular) sinuses– Cortical (trabecular) sinuses– medullary sinuses– efferent vessel

25
Q

What are the 3 zones of the germinal center of a seondary follicle?

A
  1. Dark zone (DZ)
  2. apical light zone (LZ)
  3. Marginal zone (MZ)
26
Q

What happens when thoracic duct is ruptured?

A

Chylothorax

27
Q

what are the 5 functions of the spleen?

A
  1. filters blood
  2. samples/removes antigens from blood
  3. Mounts immune response against blood borne antigens
  4. hematopoiesis in fetus
  5. stores RBCs and platelets
28
Q

Which species does not have a storage- type spleen?

A

cats

29
Q

What are the 2 portions of Red Pulp in the spleen?

A
  1. parenchyma

2. venous sinuses

30
Q

What makes up the parencyma of the red pulp

A

macrophages

31
Q

What makes up the venous sinuses in red pulp?

A

long endothelial cells and basement memb.

32
Q

What does the parenchyma of white pulp contain?

A

b cells and t cells

33
Q

What are the mucosal associated lymphoid tissues?

A
  1. GALT
  2. BALT
  3. Tonsil
  4. Ocular
  5. Urogenital
  6. Mammary
34
Q

What are GALT?

A

Gut-associated lymphatic tissue

35
Q

What are the 5 GALTs?

A
  1. Solitary and aggrigated lymph nodes
  2. Intraepithelial lymphocytes
  3. subepithelial lymphocytes
  4. Plasma Cells
  5. Macrphages
36
Q

What are Peyer’s patches?

A

Aggregated lymphatic nodules located in the small intestine

37
Q

Blind-ended lymphatic capillaries within intestinal vili of small intestine

A

Lacteals

38
Q

What are M-Cells?

A

Specialized epithelial cells found in peyer’s patch that secrete contento on the lymphocytes and macrophages

39
Q

Aggregated lymphatic nodules in pharynx

A

Tonsils

40
Q

T/F tonsils do not contain lymphatic vessels.

A

T

41
Q

Where are lymphatic vessels not located?

A

eye, cartilage, bone, spleen, CNS

42
Q

T/F. The flow of lymph from periphery to heart is bidirectional?

A

F. Unidirectional

43
Q

What prevents backflow in lymphatic vessels?

A

One way valves

Micro Anatomy (16 decks)

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