Exam 3-9 Flashcards
1
Q
Dalfampridine
A
symptom management of MS, improve walking speeds
-K+ channel block to improve nerve function
2
Q
cholera sx
A
NVD and dehydration
3
Q
infectious dose of cholera
A
10^8
4
Q
CTX
A
alpha = active
- B= transporter (binds to GM1 gang receptor)
- a cleaved off and binds to G protein (continuous production of cAMP)
5
Q
CFTR in cholera
A
- Ca2+ and cAMP lead to Cl-secretion
- luminal
6
Q
Zot
A
- tight junction disassembly
- efflux of salt and water
7
Q
ace
A
binds to LDL receptor
8
Q
dynamin
A
pinches off neck of vesicle
9
Q
lipid rafts are regions high in
A
cholesterol and signaling molecules
10
Q
calveolin
A
make up calveoli (1, 2 and 3)
11
Q
______ domains of misfolded protein aggregate
A
hydrophobic
12
Q
hsp 70
A
binds exposed hydrophobic regions
uses ATP
13
Q
hsp 60
A
barrel-like, has isolation chamber
uses ATP
14
Q
ERp57
A
enzyme in ER for protein folding (S-S bond formation)
