Exam 3-14 Flashcards
pertussis toxin
Galpha i/o, lock in inactive state, no activation
vibrio cholera
Galpha s, inhibits GTPase actiivty, no deactivation
sympathetic uses NTs
NE and epi
parasymp uses NTs
Ach
B1 stimulates
AC and cAMP
A1 stiumlates
PLC and lipid signals
M2 inhibits
AC
M3 stim
PLC
B ag and antag
ag: NE or Epi
antag: -olol
A ag and antag
ag: pheyl
antag: prazosin
A and B blocker effects on HR
decrease
m2 ag and antag
ag: muscar…
antag: atropine
PDE inhib
caffeine, theroplyline, rolipralm, thilinonine, viagra
atropine and epineph effect on HR
increase
B - agonist effect on lungs
bronchodilator
PKA phosphorylation inhibits smooth muscle ______
contraction
m3 antag
atropine and ipratropin
Ca2+ stimulates smooth muscle _____________
contraction, bronchoconstruction
ipatropium and albuterol relive asthma?
yes