Exam 3-14 Flashcards

1
Q

pertussis toxin

A

Galpha i/o, lock in inactive state, no activation

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2
Q

vibrio cholera

A

Galpha s, inhibits GTPase actiivty, no deactivation

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3
Q

sympathetic uses NTs

A

NE and epi

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4
Q

parasymp uses NTs

A

Ach

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5
Q

B1 stimulates

A

AC and cAMP

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6
Q

A1 stiumlates

A

PLC and lipid signals

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7
Q

M2 inhibits

A

AC

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8
Q

M3 stim

A

PLC

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9
Q

B ag and antag

A

ag: NE or Epi
antag: -olol

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10
Q

A ag and antag

A

ag: pheyl
antag: prazosin

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11
Q

A and B blocker effects on HR

A

decrease

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12
Q

m2 ag and antag

A

ag: muscar…
antag: atropine

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13
Q

PDE inhib

A

caffeine, theroplyline, rolipralm, thilinonine, viagra

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14
Q

atropine and epineph effect on HR

A

increase

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15
Q

B - agonist effect on lungs

A

bronchodilator

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16
Q

PKA phosphorylation inhibits smooth muscle ______

A

contraction

17
Q

m3 antag

A

atropine and ipratropin

18
Q

Ca2+ stimulates smooth muscle _____________

A

contraction, bronchoconstruction

19
Q

ipatropium and albuterol relive asthma?

A

yes