Exam 2; Gingival Diseases 2 Flashcards
What are the characteristics of lichen planus
characteristic skin lesions (wickham striae)
oral involvement alone is common
various clinical appearances
any area of the oral mucosa
This is a small, inflammatory, congested spot on the skin, a pimple
papula
this is a mesh; in the form of a network
reticular
this is a patch on the skin or on a mucous surface
plaque
This is wasting, a decrease in the size of tissue
atrophy
This is affected with an ulcer, open sore or lesion of the skin or mucosa accompanied by the sloughing of inflamed necrotic tissue
ulcerative
This is a large blister or skin vesicle filled with fluid
bulla
Lichen plans can also look like this
oral lichenoid lesions
What are three examples of oral lichenoid lesions
lesions in contact with dental restorations
lesions associated with various types of restorations
a group of systemic diseases
What is the treatment for oral lichenoid lesions
biopsy
take sample for culture if questioning candida
traumatic plaque control
topical corticosteroids to control pain, discomfort
This is a group of disorders in which autoantibodies towards components of the basement membrane result in detachment of the epithelium from the connective tissue
pemphigoid
What is the histology behind pemphigoid
autoantibody reactions against hemidesmosomes and lama lucida components
Pemphigoid results in deposits of what things
C3
IgG
other Ig’s
What are the three types of pemphigoids
bullous
benign mucous membrane
cicatrical (scar formation)
What is the nicholsky sign
rubbing of the gingiva creates bulla formation
What is the treatment for pemphigoid
plaque removal with daily use of chlorahexidine and/or topical corticosteroid
This results from the formation of intraepithelial bullae in the skin and mucous membranes; painful desquamative lesions, erosions, or ulcerations
pemphigus vulgaris
Which group of people is more susceptible to pemphigus vulgaris
strong genetic background in Jewish and Mediterranean
typically in the middle aged or elderly
What is the histology being pemphigus vulgaris
acantholysis (due to destruction of the desmosomes)
pericellular epithelial deposits of IgG and C3
circulating autoantibodies against intraepithelial adhesion molecules
This is an acute, sometimes recurrent vesiculobullous disease affecting both mucous membranes and the skin; swollen lips often with extensive crust formation of the vermillion border; oral involvement in 25-60% of cases
erythema multiforme
What are the characteristics of erythema multiforme
bullae that rupture and leave extensive ulcers
characteristic skin lesions (iris appearance + bulla)
extensive necrosis; Stevens-Johnson
may occur at any age buy mostly young individuals