Exam 2; Aggressive Periodontitis Flashcards

1
Q

What are the overall characteristics of AP

A

non-contributary medical history
rapid attachment and bone loss
familial aggregation
lack of consistency between bacterial deposits and severity of breakdown

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2
Q

This is important when recognizing AP

A

early detection

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3
Q

Which group of people is more prone to AP

A

children/adolescents

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4
Q

What are four specific indicators of AP

A

marginal bone loss
presence of clinical attachment loss
increased probing depths
plaque

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5
Q

There is an absence of this when diagnosing the localized form of AP

A

systemic disease that may severely compromise host response or lead to premature exfoliation of teeth

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6
Q

What is the distribution of localized AP

A

not more than 2 teeth are affected in addition to the first molars and incisors

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7
Q

What is the clinical outcome of LAP

A

severe destruction of periodontal tissues in a short time

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8
Q

What are two possible reasons for destructive process

A

aggressive causative agents

high level of susceptibility

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9
Q

What is one of the main bacterial etiologies in LAP

A

AA

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10
Q

This is one of the main pathologies of AA

A

leukotoxin

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11
Q

These levels are pretty high in regards to AA

A

Ab levels

IgG2 levels

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12
Q

What are some genetic factors of LAP

A

familial aggregation
most likely substantial genetic polymorphism
proposed model = autosomal dominant

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13
Q

This has been shown to increase the likelihood of GAP but not so much LAP

A

smoking

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14
Q

L/GAP is what type of factorial disease

A

multifactorial disease

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15
Q

L/GAP can result from an imbalance in what

A

host genes and environment

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16
Q

This is necessary to cause L/GAP

A

exposure to a pathogen and the host’s inability to deal with it to avoid damage

17
Q

This of L/GAP is determined by modifying environmental (smoking) or genetic factors

A

phenotype

18
Q

What is the pathogenesis of AP

A

normal to LAP to GAP

19
Q

What two things can cause normal to go to LAP

A

exposure to bacterial infection; AA

genetic predisposition

20
Q

What three things can cause LAP to go to GAP

A

smoking
other bacteria
genetic modifying factors

21
Q

What are some questions to answer when diagnosing L/GAP

A
is there periodontitis
match of plaque/calculus/local factors with periodontal destruction
systemic component
microbiological diagnosis
other family members
host defenses
22
Q

What are four treatment principles of L/GAP

A

referral to a periodontist
elimination or suppression of microflora
address environmental factors
provide environment conducive to long term maintenance