Exam 1: Hormones Flashcards

1
Q

Estradiol 17B is metabolized here

A

LIVER

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2
Q

This horse-specific estrogen is synthesized in large amounts

by the placenta in pregnancy and can be given PO

A

Equilin, equilinin

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3
Q

Progesterone is produced mainly by the ovary,

but specifically by the _________

A

corpus luteum

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4
Q

What is the critical function of progesterone?

A

Maintenance of pregnancy

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5
Q

5-a-dihydroprogesterone is a proestagen

that is critical for maintenance of pregnancy in

which species?

A

horses

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6
Q

The reason for demise of progesterone is the production

of _________ from the uterus

A

PGF2a

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7
Q

The dominant follicle differs from other follicles

because they have _______ receptors,

A

dominant follicle has LH receptors

(the others are FSH dependent)

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8
Q

The dominant follicle starts making more

estradiol and inhibin

which suppresses ________

so that the subordinate follicles undergo ATRESIA

A

FSH

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9
Q

What are the 3 reproductive

STEROID hormones?

A

Estradiol (E2)

Progesterone (P4)

Testosterone (T)

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10
Q

Estradiol is produced

in the ovary by __________ cells in females

and in the testis by __________ cells in males

A

Estradiol

granulosa cells- females

sertoli cells- males

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11
Q

Progesterone is produced by which 2 structures?

A

Corpus luteum

and

Placenta

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12
Q

Testosterone

is produced by the _________ cells

in the theca interna

A

Leydig cells

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13
Q

What are the 6 reproductive

GLYCOPROTEIN hormones?

A

Inhibin

Activin

LH

FSH

hCG

eCG

IE HALF

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14
Q

Inhibin, a glycoprotein hormone,

is responsible for inhibition of _______

A

FSH

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15
Q

Inhibin is produced by

the ________ cells of the ovary in females

and by

the ________ cells of the testis in males

A

Inhibin

granulosa cells- females

sertoli cells- males

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16
Q

Activin stimulates ________ secretion

A

FSH

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17
Q

Activin is produced by which 3 structures?

A

Granulosa cells

Sertoli cells

Placenta

18
Q

This reproductive hormone is a

DECAPEPTIDE

A

GnRH

19
Q

GnRH is produced by the

A

hypothalamus

20
Q

GnRH controls the release of _____ and ______

A

FSH, LH

21
Q

The target of GnRH is the _____ pituitary

A

anterior

(controls release of FSH and LH)

22
Q

LH, produced by the anterior pituitary,

targets the ________ cells of the testis in males

and the _______ and ________ cells in females

A

LH, produced by the anterior pituitary,

targets the Leydig cells of the testis in males

and the theca interna and luteal cells in females

23
Q

What is the action of LH in males?

A

stimulate testosterone production

24
Q

What is the action of LH in females?

A

Androgen and Progesterone production

and

Ovulation

25
Q

FSH targets the

________ cells of the testis in males

and the

________ cells of the ovary in females

A

sertoli cells

granulosa cells

26
Q

What is the action of FSH in males?

A

Sertoli cell function and estradiol synthesis

27
Q

What is the action of FSH in females?

A

Follicle development and estradiol synthesis

28
Q

Prolactin (PRL) is a luteotrophic hormone

produced by the _______ cells

of the anterior pituitary

A

lactotrope

29
Q

Prolactin targets which 2 structures in males?

A

Testis and brain

30
Q

Prolactin targets these 3 things in females

A

Mammary cells

Corpus luteum

Brain

31
Q

This hormone is an octapeptide

synthesized in the hypothalamus,

stored/secreted by the posterior pituitary,

and

synthesized in the CL

A

Oxytocin

32
Q

This hormone acts on the epididymal tail, ductus deferens,

and ampulla to control

PGF2a synthesis and ejaculation in males

A

Oxytocin

33
Q

This hormone acts on the

myometrium, endometrium, and mammary glands

to control uterine motility, PGF2a synthesis, and milk ejection

in females

A

Oxytocin

34
Q

Prostaglandin F2a (PGF2a)

is a lipid hormone produced by the

________ in females

and the

________ in males

A

endometrium- females

accessory glands- males

35
Q

What is the function of PGF2a in males?

A

sperm metabolism, epididymal contraction

36
Q

What is the function of PGF2a in females?

A

Luteolysis, myometrial contraction, ovulation

37
Q

This lipid hormone is a luteotrophic that controls

ovulation and embryo movement

by acting on the follicle, CL, and uterine tubes.

A

Prostaglandin E2 (PGE2)

38
Q

What are the 4 sources of prostaglandin E2 (PGE2)?

A

Ovary

Uterus

Embryo

Placenta

39
Q

This glycoprotein hormone

is produced by the trophoblast (chorion)

and targets the fetal testis and ovary

A

hCG

(Human chorionic gonadotropin)

40
Q

This glycoprotein hormone is produced by the

chorionic girdle cells (endometrial cups)

and targets the ovary to act on the accessory CL

A

Equine chorionic gonadotropin (eCG)