Etiology and Pathogenesis of Upper Genital Tract Neoplasia

Question 1

What is the most common malignancy of the female genital tract in developed countries?

Answer 1

Endometrial adenocarcinoma

Question 2

What is the mean age of diagnosis for endometrial cancer?

Answer 2

63 years

Question 3

What is the most common presenting symptom of endometrial cancer?

Answer 3

Abnormal uterine bleeding

Question 4

What is the main risk factor for type 1 endometrial cancer?

Answer 4

Unopposed estrogen exposure

Question 5

What is the primary treatment for operable endometrial cancer patients?

Answer 5

Total hysterectomy + bilateral salpingo-oophorectomy + surgical staging

Question 6

What is the 5-year survival rate for type 1 endometrial cancer?

Answer 6

0.86

Question 7

What is the lifetime risk of ovarian cancer?

Answer 7

0.016

Question 8

What is the most lethal gynecological malignancy?

Answer 8

Ovarian cancer

Question 9

What is the standard treatment for ovarian cancer?

Answer 9

Total abdominal hysterectomy with bilateral salpingo-oophorectomy and comprehensive surgical staging

Question 10

What is the 5-year survival rate for localized ovarian cancer?

Answer 10

0.925