Endocrine System (Lecture) Flashcards
Exocrine vs Endocrine
Exocrine releases hormones into ducts and endocrine releases hormones in to the blood stream
Target cells
Have receptors for specific hormone
i.e. APG -> TSH -> only thyroid cells have receptors for it
APG -> growth hormone -> all cells
What is the pituitary gland?
Master gland
- sits in sella turcica; sphenoid bone
- PRL, TSH, GH, LH, FSH, ACTH
- oxytocin -> milk release
- ADH -> kidney water retention
Thyroid gland
Releases TSH -> thyroid hormone -> regulates metabolism
- thyroid follicles -> contain thyroid hormone
- parafollicular cells -> calcitonin -> activates osteoblasts -> lowers blood calcium levels
What is goiter?
- inflamed thyroid gland
- from iodine deficiency
- iodine needed for TH
Parathyroid glands
Parathyroid hormone ->activate osteoclasts -> increase blood calcium levels
Adrenal gland
Adrenal cortex
- steroid hormones (cortisol)
Adrenal medulla
- adrenaline (epinephrine)
Pancreas
Digestive and endocrine organ
What are pancreatic acini?
Exocrine glands that release digestive enzymes “pancreatic juice”
What is Islet of Langerhans?
Endocrine glands that release:
insulin: decrease BGL; works on all cells
glucagon: increase BGL; acts on liver and adipose tissue to release glycogen
Describe type I Diabetes
- juvenile onset
- autoimmune disorder
- attacks beta-cells
Tx: insulin and immunosuppressant
Describe type II diabetes
- adult onset
- result of poor diet and exercise
- increased resistance to insulin due to overexposure
Tx: Exercise, diet, and medication