Cells & Tissues (Lecture) Flashcards
Plasma Membrane
Membrane that surrounds the cell
Plasma membrane structure?
Phospholipid bilayer
Cholesterol
Proteins
Phospholipid bilayer
Separates the cell from the extracellular fluid
What does cholesterol do for the cell?
Stabilizes membrane fluidity
Plasma membrane proteins
Allow material to enter/exit cell. Also allows for communication between cells
All cells:
- Maintain homeostasis
- Undergo metabolism to make ATP
- Respond to environment
- Made of carbs, lipids, proteins, and nucleic acid
Differentiated Cells
Specific function and cell shape
Stem Cells
Undifferentiated cells that divide indefinitely
Stem cell types
Daughter cells
Unipotent stem cells (osteoblasts)
Pluripotent stem cells (blood stem cells)
Totipotent stem cells (fertilized egg)
Organelles
Structures within a cell that carry our particular functions. (Must be surrounded by membrane)
Cytosol
Liquid that organelles float in. Mostly made of water with dissolved ions, nutrients, etc.
Cytoplasm
Everything between the plasma membrane and the nucleus
Nucleus
Largest organelle, stores DNA and makes RNA
Nucleolus
Region within nucleus that makes ribosomes
Mitochondria
Makes ATP from glucose
Rough endoplasmic reticulum
Has ribosomes to make secretory proteins, membrane proteins, and organelle proteins
Golgi Apparatus
Packages proteins into vesicles and sends them to proper location
Vesicles:
- transport vesicles
- secretory vesicles
- storage vesicles
Lysosome
Containing digestive enzymes. Digests old organelles, etc. (apoptosis)
Smooth Endoplasmic Reticulum
Metabolism of Carbohydrates and lipids. Stores calcium, and detoxifies
Free Ribosome
Structures that are used to read RNA and make proteins that stay in the cytosol
Cytoskeleton
Made of protein filaments:
- microtubules
- microfilaments
- intermediate filament
Microtubules
- Maintain cell shape
- allows movement within cell
Microfilament
- cell movement
- change cell shape (actin & myosin)
Intermediate Filament
Give cells physical strength (keratin)
Simple Squamous Epithelium is found where?
Found where lots of diffusion is required
Simple cuboidal epithelium are found where?
Found in areas of some diffusion (glands)
What are some characteristics of a Simple columnar epithelium?
May have goblet cells: secrete mucus
Pseudostratified columnar epithelium
Always have goblet cells
Ciliated vs. Non-ciliated
Stratified Epithelial Tissue purpose and the different types
Provides protection against abrasions
- Stratified squamous epithelia
- Stratified cuboidal
- Transitional epithelium
Stratified squamous epithelia
- Keratinized (only in epidermis)
2. Non-keratinized (mouth, throat, vagina, anus)
Stratified cuboidal
Line ducts
Transitional Epithelium
Stretch (bladder, urethra, etc)
Types of connective tissue
- Fibrous CT
2. Special CT
Components of all Fibrous CT
Cells:
- Fibroblasts
- leukocytes
- adipocytes
Extracellular Matrix:
- Interstitial fluid
- collagen fibers
- elastic fibers
- reticular fibers
- Blood vessels
- nerves
Fibroblasts
Make protein fibers (ex. collagen)
Leukocytes
Macrophages, mast cells (release histamine)
Adipocytes
Store fat
Collagen fibers
Give strength, turn H2O to gel
Reticular Fibers
Create mesh to hold cells in place
Interstitial fluid contains what?
Contain H2O, gas, hormones, and waste
Blood vessels role for cells
Leak plasma; become ECM
Nerves
Provide sensation
Types of fibrous CT
Loose and dense fibrous. Loose fibrous CT contain more ground substance, less fiber. Dense fibrous CT contain less ground substance, more fiber.
Types of loose fibrous CT
Areolar CT: underneath all ET
Adipose tissue: Store fat
Reticular CT: create a net to hold cells in place
Type of dense fibrous CT
Dense regular CT: collagen fibers run parallel (strong in 1 direction) ex: Ligament
Dense Irregular CT: collagen fibers different directions (multi-directional strength) ex: skin
Epithelial Tissue function and attributes
- Form a continuous layer of cells
- All attached to basement membrane. Its function is to attach to ET and CT and act as a filter between ET and CT
- Avascular; nutrients and O2 come from areolar CT
- polarity; basal surface and apical surface
Intercellular Junctions types
1: Tight Junction
2. Desmosomes
3. Gap junction
Tight Junction function?
Closes gap between cells
Desmosomes
1: physically attach cells
2: Attached to intermediate filaments
Gap Junctions
Open channel between cells to allow for communication
How to classify ET
- Structure
-simple vs stratified
-shape - Function
-Dry
-moist
I. mucosae-lined with mucus
II. Serosae watery substance
Types of special CT
- cartilage
- Bone tissue
- blood
Cartilage characteristics and types
semi-solid ECM; avascular
- Hyaline Cartilage
- fibrocartilage
- elastic cartilage
Bone tissue types
Rigid ECM
- Compact bone
- spongy bone
Blood has what kind of ECM?
Fluid ECM
Muscle Tissue
Skeletal Muscle
Cardiac Muscle
Smooth Muscle
Exocrine Glands
glands that secrete into ducts
Classification of glands
- type of secretion
- method of secretion
- structure
Glands based on type of secretion
- serous gland (watery) ex. sweat glands
- mucous gland
- mixed gland (serous and mucous secretion) ex: salivary gland
- oil gland (oil/waxy) ex: sebaceous gland
Glands based on method of secretion
- merocrine gland (exocytosis) ex: most sweat glands,, mucus glands
- apocrine glands (break off apical PM) ex: mammary gland, prostate gland
- holocrine gland (entire cell dissolves) ex: sebaceous gland
Glands based on structure
- Unicellular gland. ex: goblet cell
- Multicellular gland
i. tubular or alveolar gland
a. simple (1 duct) ex: sweat gland (simple tubular)
b. compound (2+ ducts) ex: mammary gland ( compound alveolar)
apoptosis
planned destruction of cells
Benign Tumor
non-cancerous. tx: removal
Cancer Stages
0. Benign Growth I. Broke through base membrane II. spread into connective tissue III. Entered bloodstream IV: Metastasis
Carcinoma
Epithelial Tissue Cancer
Metastasis
Developed past origin point
Sarcoma
Connective Tissue Cancer