Endocrine System Flashcards

1
Q

Functions of Endocrine System

A
water balance
uterine, contraction and milk release
growth, metabolism and tissue maturation
ion regulation
heart rate and blood pressure regulation
blood glucose control
immune system regulation
reproductive functions control
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2
Q

a mediator molecule that is released in one part of the body but regulates activity of cells in other parts of the body

enters interstitial fluid and then the blooodstream

A

hormone

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3
Q

mediator molecules

A

nervous: neurotransmitter
endocrine: hormone

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4
Q

site of mediator action

A

nervous: close to site
endocrine: far

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5
Q

types of target cells

A

nervous: muscles
endocrine: all body cells

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6
Q

time to onset of action

A

nervous: milliseconds
endocrine: seconds to hours to days

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7
Q

duration of action

A

nervous: brief
endocrine: longer

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8
Q

other name of pituitary gland

A

hypophysis

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9
Q

other name of posterior pituitary gland

A

neurohypophysis

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10
Q

does not synthesize hormones but only stores and release 2 hormones

A

posterior pituitary gland

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11
Q

hormones stored by PPG

A

ADH

Oxytocin

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12
Q

target organ and function of ADH

A

kidney

increases water reabsorption

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13
Q

other name of ADH

A

vasopressin

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14
Q

target organ and function ocytocin

A

uterus (muscle layer-myometrium)
mammary glands

increases uterine contraction
increases milk “let down” from mammary glands

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15
Q

oxytocin is used only for a few months and replaced by

A

prolactin

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16
Q

stalk connecting pituitary to hypothalamus

A

infundibulum

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17
Q

other name of anterior pituitary gland

A

adenohypophysis

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18
Q

composed of epithelial tissues

secretes hormones that regulate a wide range of bodily activities from growth to reproduction

A

anterior pituitary gland

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19
Q

hormones synthesized by APG

A
GH
TSH
Adrenocorticotropic Hormone
MSH
LH or ICSH
FSH
Prolactin
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20
Q

cells that produce GH

A

somatotrophs

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21
Q

cells that produce TSH

A

thyrotrophs

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22
Q

cells that produce adrenocorticotropic hormone

A

corticotrophs

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23
Q

cells that produce LH and FSH

A

Gonadotrophs

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24
Q

cells that produce Prolactin

A

lactotrophs

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25
target organ and response of GH
most tissues increases protein synthesis, breakdown of lipis and release of fatty acids from cells increase blood glucose level
26
target organ and response of TSH
thyroid gland increases thyroid hormone secretion (T3,T4)
27
target organ and response of Adrenocorticotropic hormone
adrenal cortex increases secretion of glucocorticoid hormones such as cortisol increases skin pigmentation at high concentrations
28
target organ and response of melanocyte-stimulating hormone
melanocytes in skin increases production of melanocytes to make the skin darker in color
29
target organ and response of LH
ovary testes promotes ovulation and progesterone production in ovary testosterone synthesis and support for sperm cell production in testis
30
target organ and response of FSH
follicles in ovary seminiferous tubules in males promotes follicle maturation and estrogen secretion in ovary sperm cell production in testis
31
target organ and response of Prolactin
ovary and mammary glands testis stimulates milk production and prolongs progesterone secretion following ovulation and during pregnancy in women increases sensitivity to LH in males
32
hormones secreted by thyroid gland
``` thyroid hormone (thyroxine/triiodotheyronine) calcitonin ```
33
target organ and response of thyroid hormone
most cells of the body Increases metabolic rates, essential for normal process growth and maturation
34
target organ and response of calcitonin
priamarily bone decreases rate of bone break down prevents large increase in blood calcium levels following a meal
35
4 small glands at posterior portion of thyroid glands
parathyroid glands
36
hormone secreted by parathyroid glands
parathormone
37
other names of parathormone
paracalcitonin | parathyroid hormone
38
target organ and response of parathormone
bone increases rate of bone breakdown by osteoclast kidney increases vitamin D synthesis, essential for maintenance of normal blood calcium levels
39
both endocrine and exocrine functions
pancreas
40
endocrine function of pancreas
digestive system
41
hormones secreted by pancreas
insulin | glucagon
42
target organ and response of insulin
liver, skeletal muscle, adipose tissue Increases uptake and use of glucose and amino acids liver Increases breakdown of glycogen and release of glucose into the circulatory system
43
cluster of endocrine cells in pancreas
Islets of langerhans
44
other name of Adrenal glands
suprarenal glands
45
superior to kidneys
adrenal glands
46
inner layer; modified extension of nerve fibers from sympathetic nervous system
adrenal medulla
47
outer layer
adrenal cortex
48
hormones secreted by adrenal medulla
epinephrine and some norepinephrine
49
target organ and response of epinephrine and norepinephrine
heart, blood vessels, liver, fat cells increases cardiac output increases bloodflow to skeletal muscles and heart increases release of glucose and fatty acids into blood
50
hormones secreted by adrenal cortex
mineralocorticoids glucocorticoids adrenal androgens
51
target organ and response of mineralocorticoids
kidney increases rate of sodium transport into body increases rate of potassium excretion secondarily favor water retention aldosterone (stimulate posterior pituitary gland to release ADH)
52
target organ and response of glucocorticoids
most tissues (liver, fat, skeletal muscle, immune tissues) increase fat (glycolysis) and protein breakdown increase glucose synthesis from amino acids (gluconeogenesis) increases blood nutrient levels inhibit inflammation and immune response
53
target organ and response of adrenal androgens
most tissues insignificant in males increase female sexual drive, pubic hair, axillary hair growth; converted to estrogen
54
3 parts of adrenal cortex
zona glomerulosa zona fasciculata zona reticularis
55
zona glomerulosa
mineralocorticoids
56
zona fasciculata
glucocorticoids
57
zona reticularis
androgens
58
most abundant mineralocorticoids
aldosterone
59
most abundant glucocorticoids
cortisol
60
hormones secreted by ovary
estrogen and progesterone
61
target organ and response of estrogen and progesterone
most tissues and in uterus and mammary gland development and function, external genitalia structure, secondary sexual characteristics, sexual behavior and menstrual cycle
62
hormones secreted by testes
testosteron
63
target organ and response of testes
most tissues aids in cell production, maintenance of functional reproductive organs, secondary sexual characteristics and sexual behavior
64
produces testosterone
leydig cells
65
hormones secreted by thymus gland; aids in maturation of T-cells
thymosin
66
target organ and response of thymosin
immune tissues promotes immune system development and function
67
b cells mature in
bones
68
hormones produced by pineal body
melatonin
69
target organ and response of melatonin
hypothalamus | inhibits secretion of gonadotrophin-releasing hormone, thereby inhibiting reproduction
70
urine production
diuresis
71
follicular cells
t3 and t4
72
parafollicular cells
calcitonin
73
excessive production of GH
giantism
74
low production of GH
dwarfism
75
extended width of bone
acromegaly
76
produces glucagon; few
alpha cells
77
produces insulin; majority
beta cells