Blood Flashcards

1
Q

Function of Blood

A

Transportation
Regulation
Protection

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2
Q

Composition of Blood

A

55% Plasma

45% Blood Cells

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3
Q

fluid portion of blood

watery, liquid matrix that contains dissolved substances

A

Plasma

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4
Q

Composition of Plasma

A

91-91.5% water
1.5-2% other solutes
7% proteins

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5
Q

proteins

A

albumin (produced in liver)
globulin
fibrinogen

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6
Q

function of albumin

A

maintain oncotic osmotic pressure

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7
Q

edema

A

plasma accumulating in extravascular/ interstitial space

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8
Q

ascites

A

accumulation of excess fluid in peritoneal cavity

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9
Q

globulin that binds and transports iron

A

transferrin

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10
Q

other examples of globulin

A

IGg

IGm

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11
Q

Fibrinogen is converted into

A

fibrin

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12
Q

function of fibrin

A

clotting

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13
Q

final product of ammonia (toxic)

A

urea

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14
Q

formed elements of blood

A

Blood Cells

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15
Q

Composition of Blood cells

A

95% RBC

5% WBC and Platelets

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16
Q

shape of RBC

A

biconcave, disc-shaped

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17
Q

diameter of RBC

A

7-8 um

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18
Q

description of RBC

A

has no nucleus
strong flexible membrane
contains hemoglobin
transports oxygen

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19
Q

oxygen-carrying protein

A

hemoglobin

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20
Q

1 hemoglobin=

A

4 irons, 4 O molecules

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21
Q

1 RBC =

A

4 million hemoglobin molecules

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22
Q

increase in RBC

A

Erythrocytosis

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23
Q

decrease in RBC

A

Erythropenia

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24
Q

normal RBC count

A

M- 5.4 million/microliter

F-4.8 million/microliter

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25
lifespan of RBC
120 days
26
a hormone secreted by the kidneys that stimulates Red Bone marrow to produce RBC
erythropoietin
27
percentage of total blood volume occupied by RBC
Hematocrit
28
normal vol.
M - 40-46% (ave. 47%) | F - 38-46% (ave. 42%)
29
storage form of iron in liver
Ferritin
30
concentrates bile
Gallbladder
31
emulsifies fats
bile
32
green pigment
Biliverdin
33
yellow pigment
bilirubin
34
reason for yellow urine
urobilin
35
reason of brown stool
stercobilin
36
Classifications of Leukocytes
``` Granular Leukocytes (Red bone marrow) Agranular Leukocytes (Lymphatic Tissue) ```
37
NV = 60 - 70% most common WBC Small cytoplasmic granules that stain with acidic and basic dyes Nuclei commonly lobed (2-4) remain in blood for short time (10-12 hrs) move to other tissues
Neutrophils
38
Function of Neutrophils
Phagocytize microorganisms and other foreign substances
39
neutrophils respond to
acute bacterial infection
40
NV = 2-4% granules stain bright red with eosin - acid stain 2- lobed nucleus
Eosinophils
41
Function of Eosinophils
release chemicals that reduce inflammation (allergy) | produce chemicals involved with destruction of certain worm parasites
42
NV = 0.5 - 1 % | large cytoplasmic granules that stain blue or purple with basic dyes
Basophils
43
Function of basophils
liberate histamine, serotonin and other chemicals that promote inflammation release heparin which prevent formation of clot
44
NV = 20-25% smallest WBC cytoplasm only consists of thin, sometimes imperceptible ring around nucleus
Lymphocytes
45
types of lymphocytes
B cells T cells Natural Killer cells
46
Lymphocytes activate during
viral infection
47
function of lymphocytes
produce antibodies and other chemicals that destroy microorganisms
48
develop into plasma cells which secrete antibodies
B cells
49
attack invading viruses, cancer cells and transplanted tissue cells
T cells
50
attack invading and wide varieties of infectious microbes
Natural Killer cells
51
NV = 3-8% largest WBC cytoplasm is blue-gray and has foamy appearance nucleus is kidney-shaped or horse-shoe shaped
Monocytes
52
Function of monocytes
phagocytosis (after transformed into fixed of wandering macrophages) phagocytize bacteia, dead cells, cell fragments and other debris within tissue break down phagocytized cell and present to lymphocytes resulting in activation of lymphocytes
53
monocytes respond to
chronic phase of infection
54
other name of platelets
thrombocytes
55
fragments enclosed by a piece of plasma mebrane | NV 150,000-400,000 uL
platelets
56
function of platelets
helps stop blood loss by damaged blood vessels by forming platelet plug
57
other name of blood clotting
coagulation
58
network of threadlike protein fibers called fibrin that traps blood cells, platelets and fluid
clot
59
system used to categorize human blood
ABO blood group
60
located on surface of RBC
Antigen
61
located on plasma
Antibody
62
rupture of RBCs and release of hemoglobin into plasma
hemolysis
63
agglutination
clumping
64
other name of HDN (Hemolytic disease of newborn)
Erythroblastosis Fetalis
65
vaccine for HDN
RhoGam
66
normal blood pH
7.35-7.45 | slightly alkaline