Endocrine Drugs Flashcards
Sulfonylureas drugs end in and one example
ide
Eg. Glicazide
Dpp4 inhibitors end in … and 1 example
Gliptin
Eg. Sitagliptin
GlP-1 agonists end in… + 1 example
Tide
Eg. Semagulitide (ozempic)
What drugs act like insulin?
Give example
Thiazolidinediones
Eg. Pioglitazone
When is pioglitazone contraindicted?
What type of drug is pioglitazone
If the patient has/had bladder cancer
heart failure (it causes urinary retention)
Thiazodene
Sulfonyurea SE
weight gain
Hypoglycaemia
drugs ending in flozin are…
SGLT2 inhibitors (eg. dapagliflozin)
metformin is contraindicted in…
and se
CKD- egfr of <30
GI issues, lactic acidosis
DPP4 inhibitors side effects
GLiptins:
pancreatitis
SGLT2 side effects
thrush
necrotising fascitis
Which diabetic drug most effective at causing satiety and leading to weight loss in patients with t2 diabetes
GLP-1
Most common metformin side effect
GI upset
What diabetic drugs cause weight gain
insulin and sulfonyureas (eg. glipizide)
for combination therapy what are the advantages of using a gliptin
does not cause weight gain, does not cause hypoglycaemia
advantages of using glicazide dual combination
very effective, for those who r weight neutral