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Year 2 > Derm Wrong > Flashcards

Derm Wrong Flashcards

1
Q

Function of apocrine glands

A

secrete oily scented fluid found in axillae and perineum

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2
Q

Function of eccrine glands

A

secrete sweat for temperature regulation, found everywhere

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3
Q

Label it (left to right)

A
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4
Q

How would this lesion be described

A

Lichenification (feature is leathery skin)

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5
Q

What term can be used to describe the heel of this patient?

A

Maceration
(What happens to the skin after a prolonged exposure to moisture)

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6
Q

What term would describe what has happened to the skin of this patient?

A

Erosion (the loss of epidermis)

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7
Q

How would you describe this lesion? (1word)

A

Nodule (a rounded, irregular mass)

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8
Q

How would you describe this lesion (1word)

A

Papule (small inflammatory spot, no pus)

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9
Q

How would you describe this lesion?

A

Macule (skin discolouration)

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10
Q

What would you describe these lesions as ? (1word)

A

Vesicles (small +fluid filled)

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11
Q

Where are hemi-desmosomes found

A

Dermo-epidermal junction

(They stick basal layer to basement membrane)

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12
Q

What enzyme deficency causes poryphtria cutanea tarda
what poryphorin is accumulated

Features of presentation?

A

Uroporphyinogen decarboxylase

uroporphyrinigen 3

middle aged men
blistering in sun> scarring
Excessive hair growth (hypertrichosis)

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13
Q

What enzyme deficency causes erythopoietic protoporphyria
what poryphoria is built up

Features of the presentation

A

Ferrochtelqse defiency
protoporphyrin IX

Young child, discomfort after sun, no rash

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14
Q

What enzyme deficiency causes acute intermittient porphoryia
what poryphoria is built up

Features of presentation

A

Porphobilinogen deaminase
porphbilinogen (aka hydroxy)

woman, Acute neurotoxic reaction in tissues, mood disturbance

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15
Q

List the diff types of hypersensitivity and give a brief description of each

A

Type I- instant, IgE mediated, allergic
T II- IgG, IgM, blood serum sickness (cytotoxic)
T III- IgG, IgM, immune complex
TIV- T cell mediated, delayed, contact dermatitis

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16
Q

ABPI ranges and what it means

A

0.8-1.3 normal
<0.8 = arterial disease
>1.3= arterial calcification eg. RA

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17
Q

what depth of SCC is associated with good/bad prognosis

A

<2mm good prognosis
>4mm bad prognosis

18
Q

“slap cheek syndrome” is …
Caused by…
common in ages of…

A

erythema infectiosum
Parovirus
3-15years

19
Q

herald patch is a sign of what disease
common in ages….

A

pityriasis rosea
10y-35y
Herald patch which disapears then get loads of small red lesions on trunk/back following dermatomes

20
Q

what can exacerbate psoriasis and cause guttat psoriasis specifically

A

streptococcal throat infection

21
Q

common causes of exacerbation of plaque psoriasis

A

alcohol, propanolol

22
Q

what diseases is erythema nodosum associated with

A

IBD, tuberculosis and sarcoidosis

23
Q

What causes albinism

A

Inability to synthesise tyrosine

24
Q

What causes vitiligo

A

Autoimmune destruction of melanocytes

25
Q

during foetal development where do melanocytes migrate from

A

neural crest

26
Q

are mucosal membranes keratnised

27
Q

where are melanocytes found in the skin

A

deep layer of the dermis

28
Q

what layers of the skin do eccrine, apocrine and sebacous gladns and hair follicle originate

A

eccrine and apocrine- epidermis
sebacous- mid dermis
hair follicle- subcutis

29
Q

what cells carry out vitamin d metabolism in the skin

A

keratinocytes

30
Q

what do venous ulcers present as

A

shallow ulcers, granulated base medial malleoulus

31
Q

arterial ulcers presentation

A

punched out lesions, atrophied skin, shiny skin, cold skin and reduced pulse

32
Q

neuropathic ulcer presentation

A

punched out!, bottom of feet usually,
(kind of hard sometimes to differentiaite between arterial and neuropathic however defining features are neuropathic will still have strong pulse and warm skin)

33
Q

kapsoi sarcoma presentation and causitive organism

A

HIV + raised purple coloured patches on trunk and lesions in mouth

human herpes virus 8

34
Q

what type of melanoma is often seen in dark skinned individuals

A

acral lentignous

35
Q

what diseases present with a butterfly rash and what differentiates them

A

SLE: joint pain, fatigue, raynauds etc

Eryispleas: ACUTE, unwell (type of cellulitis)

rosacea: systemically well, spotty etc

36
Q

necrobiosis lipdoidica px

A

orange, brown atrophied skin that is shiny with telangiectasia and associated with diabetes

37
Q

Slapped cheek child what diagnosis

A

ERYTHEMA INFECTIOSUM

38
Q

Kawasaki disease presentation

A

fissured lips, friable tongue, bilateral conjunctival injection, rash on hands feet, elbows

39
Q

most agressive melanoma

A

nodular, ( 2nd most common)

40
Q

most common melanoma

A

superficial spreading

41
Q

dermatitis herpeticum causative organism

A

HSV

NOT HPV

Year 2 (50 decks)

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