Endocrine Flashcards
What are the endocrine glands ?
Ductless glands that produce hormones which go directly into the blood stream
Endocrine tissues apart from glands are-
Prostaglandin
Kidney
GI tract
Skin
Placenta
Liver
Location of hypothalamus
Base of brain
Function of hypothalamus
Secretes hormones that signals the release of hormones from the pituitary gland
What are the physiological functions affected directly by the hypothalamus?
Water balance
Sleep
Temperature
Appetite
Blood pressure
Location of pituitary gland
Sella Turcica
Two parts of pituitary gland ?
Anterior pit ( adenohypophysis)
Posterior pit ( neurohypophysis)
Hormones of adenohypophysis?
Growth hormone.
Thyroid, stimulating hormone
Adenocorticotropic hormone
Gonadotropic hormone
Prolactin
Melanocyte stimulating hormone
Another name for Growth Hormone ?
Somatotropin
Function of TSH
Thyroid stimulating hormone
Promotes growth of thyroid gland and secretion of thyroxin
ACTH function
Adrenocorticotropic hormone
Promotes growth of adrenal cortex and secretion of steroid hormone
What are the gonadotropic hormones ?
FSH
LH
Hormone responsible for milk production?
Prolactin
Hyper secretion of which hormone causes hyperpigmentation?
Melanocyte stimulating hormone
Hormones of the neurohypohysis ?
ADH
OXYTOCIN
Vasopressin is which hormone ?
ADH
Functions of ADH
Antidiuretic hormone -
Reabsorption of water by kidney
Maintain blood pressure by constricting arterioles
Which hormone stimulates contraction during labor ?
Oxytocin
Location of pineal gland ?
Below the corpus callosum in the middle of the brain
Hormone produced by pineal gland ?
Melatonin
Serotonin
Function of melatonin
Control sleep cycle
Function of serotonin
Mood stabilizer
Which gland serves as an important landmark in an X-Ray of the brain?
Pineal gland
Thyroid gland location
Anterior aspect of the neck on either side of rod the trachea
What connects the connects the two lobes of the thyroid gland
Isthmus
Hormones of the thyroid gland ?
T4- thyroxine / tetraiodothyronine
T3 - triiodothyronine
What are thyroid hormones composed of?
Iodine and tyrosine
Which hormones are responsible for maintaining metabolism of body ?
T3 T4 thyroid hormones
Which thyroid hormone is responsible for maintaining levels of calcium ?
Calcitonin
Location of parathyroid gland ?
Behind the thyroid gland
Function of parathyroid hormone?
Mobilizes the calcium stored in the bones through the blood to where it is required.
Location of thymus gland
Posterior to the sternum in the mediastinum
Hormone of thymus gland ?
Thymosin
Function of thymosin?
Development of immune responses in neonates
Location of testes ?
Scrotum
Hormones produced by testes ?
Testosterone
Function of testosterone ?
Secondary sexual characteristics in males
Ovarian hormones are ?
Estradiol
Progesterone
Function of estradiol?
Secondary sexual characteristics in females
Function of progesterone ?
Maintenance of pregnancy
Hormones of adrenal cortex ?
Glucocorticoids
Mineralocorticoids
Sex hormones
Which endocrine hormone is responsible for metabolism of sugars, fats and proteins ?
Glucocorticoids
Which endocrine hormone is responsible for metabolism of sugars, fats and proteins ?
Glucocorticoids
Which hormone has powerful anti-inflammatory effects ?
Glucocorticoids
Which is the most important glucocorticoid hormone ?
Cortisol
Maintenance of electrolytes is by which adrenal hormone ?
Mineralocorticoids
Which Mineralocorticoids hormone promotes reabsorption of Na+ ?
Aldosterone
Potassium is excreted by which hormone ?
Aldosterone
Hormones secreted by adrenal medulla?
Epinephrine
Norepinephrine
Which hormones are sympathomimetic hormones ?
Epinephrine
Norepinephrine
Hyposecretion of somatotropin causes what condition ?
Dwarfism
What is pan hypopituitarism?
All pituitary hormones are deficient
What is SIADH
Syndrome of Inappropriate ADH
Hypersecretion of ADH causes what?
Excess water retention
Hypersecretion of GH?
Acromegaly
ADH deficiency causes what?
Diabetic insipidus
Clinical symptoms of ADH deficiency ?
Polyuria polydipsia
What is goiter ?
Enlargement of thyroid gland
Thyroid level in adenomatous goiter increases or decreases ?
Increases
What is thyroid storm?
Abrupt onset of severe hyperthyroidism
Under activity of thyroid results in what condition ?
Hypothyroidism
What is cretinism?
Extreme hypothyroidism in childhood leading to lack of normal physical and mental growth
What is myxedema?
Advanced hypothyroidism in adults.
In which thyroid condition does collection of mucous takes place under the skin?
Myxedema hypothyroidism
Condition with constant muscle contraction resulting from hypocalcemia?
Tetany
What are islets of langerhans?
Endocrine cells of pancreas
What are the hormones produced by pancreas?
Insulin - beta cells
Glucagon - alpha cells
Insulin is released when glucose is ?
Above normal level
Glucagon is released when sugar is ?
Below normal levels
Hypersecretion of insulin causes what ?
Hyperinsulinism
Hypoglycemia
Role of insulin in diabetes mellitus?
Insulin insufficiency
Type 1 DM is ?
Destruction of beta cells and complete deficiency of insulin
Which DM is insulin dependent?
Type 1 DM / juvenile DM
Type 2 DM
Adult onset
Beta cells are not destroyed
Target tissue resists insulin
Ketoacidosis is commonly seen in which type of DM ?
Type 1
What is ketoacidosis?
Fats are improperly burned and leads to accumulation of ketones
What is gestational diabetes ?
Diabetes occurring in pregnant woman
During 2/3 trimester
Adrenal virilism?
Excessive secretion of adrenal androgen in females leading to male secondary sexual characteristics in woman
Excess cortisol and excess ACTH leads to what condition ?
Cushing syndrome
Long term use of glucocorticoids may lead you to what condition ?
Cushing syndrome
Hormone levels in addison disease ?
Mineralocorticoids and glucocorticoids deficiency
Excess secretion of which hormones causes dusky urine ? What is the condition ?
Hypersecretion of epinephrine and norepinephrine
Pheochromocytoma
What is cachexia?
Loss of weight with decreased food intake and increased metabolism