Electrolytes & Shock Flashcards
Hyperthermia, seizures, flushed skin, dilated pupils that react, wide QRS
TCA OD - QRS width = severity –> ventricular arrhythmia –> NaBicarb
Ascities management
Na, H2O restrict, spironolactone, furosemide paracentesis 2-4L
Anion gap
Na - (HCO3- + Cl-)
Methanol, Uremia, DKA, Lactic acidosis, Ethylene glycol, Salicylates
MUDPILES - anion gap acidosis
Inc pH –> inc albumin+Ca –> hypoCa (ionized)
Cramping, weakness, carpopedal spasm,
HypoCa, elevated phosphorous
HypoPT - d/t surgery or auto-immune
HypoCa, fatigue, weakness, depression, normal Mg, 2-HPTH, Low Phos
VitD deficiency, CKD
Hyperreflexia electrolyte abnormality
HypoCa or hypoMag –> low PTH
Grand-mal seizures, prolonged QT electrolyte abnormality
HypoCa
Normal/Low Ca, Low 1,25-OH, High Phos, High PTH
CKD –> secondary HPT
Low Ca, Short stature, 4th & 5th digits, High PTH, Phos
End organ resistance - Gs defect
S/P thyroidectomy, anxiety, fatigue, poor sleep, depression, prolonged QTc
HypoCa
Low Ca, Low PTH, High Phos
Hypoparathyroidism = surgical removal, auto-immune
Weight loss, irritable, palp, proptosis –> HTN mechanism?
Hyperdynamic circulation
Hypothyroidism mechanism of diastolic HTN
Inc systemic vasc resistance
Most common causes of hyperCa
Malignancy, primary HPT (adenoma 90%)
Malignancy vs. PHPT hyperCa
Malignancy >13, low PTH = IL-6
High Ca, high PTH, dec Phos, Sestamibi scan
Hyperparathyroid –> resect but can –> hypoCa
High Ca, High PTH levels
Primary hyperparathyroidism or Familial (low urine), Lithium
High Ca, Low PTH
Malignancy, Vit D, HTCZ, Theophylline, milk alkali
High Ca, Low PTH, High 1,25-OH
Granulomatous - Sarcoid or lymphoma
Mildly high Ca, abnormally high/normal PTH, No sx, urine Ca <0.01
Familial hypocalciuric hyperCa –> Abn Ca-sensing receptors
Tx for hyperCa
Only >14 = IVFs + calcitonin, avoid diuretics in all pts + bisphos LT
Saline non-responsive metabolic alkalosis
Cushing, Primary hyperaldosteronism, hypoK <2
Saline responsive metabolic alkalosis
Urine Cl <20, vomiting, diuretic, laxative, dehydration
Urine Cl >20, high renin, aldo, bicarb, lowK, lowNa
Diuretic abuse
Urine Cl <10
high renin, aldo, bicarb
lowK, lowNa
Vomiting or facitious diarrhea
Urine Cl >40, high renin, aldo, bicarb, lowK, normalNa
Bartter/Gitelman syndrome
Urine Cl >40, high aldo, bicarb, Na,
low renin, lowK
Primary hyperaldosteronism