Derm Flashcards
Pink, Pearly/waxy, rolled border, bleeding, ulceration
BCC = no mets but invades
Invasive cluster of spindle cells surrounded by palisaded basal cells
BCC –> wide resection 1mm
Chronic scar –> non-healing, painless, bleeding ulcer?
SCC –> punch bx
Non-healing ulcer on arm, scaling plaque w/ central ulceration, polygonal cells
SCC = UV exposure
Hyperpigmented lesion, non-healing ulcer
SCC = Marjolin ulcer
Invasive cords of squamous cells with keratin pearls, partially encrusted ulcer
SCC –> wide resection 0.5-2cm + LN dissection d/t mets
Precursor to SCC
Actinic keratosis
Hyperpigmented lesion, asymmetric, irregular, >5mm, NO HAIR
Melanoma –> mets a lot, refractory to chemo/rad, relapsing & remitting
Tx for malignent melanoma
Breslow’s depth - local resection; 1-2mm wide + LN
Malignant melanoma >4mm tx
Mets, resection and supportive care, poor prognosis
Volcano-like nodule w/ central keratotic plug
Keratoacanthoma
Scabies tx
Permthrin cream
Intergidital, groin pruritic, thread-like burrows
Scabies = 5% permethrin
Tx Lice
Permethrin 1% cream rinse
Centrally umbilicated papules on face, neck, anogential regions
Molluscum contagiosum - Poxvirus = impaired cellular immunity
Dome w/ central umbilication tx
Molluscum –> obs, liq-N, extrode plug or canthardin 0.9%
Thin hair in pre-term
Lanugo
Thick, white creamy skin in newborn
Vernix caseosa
Benign, small and dry vesicles
Pustular melanosis
Salmon patch
Nevus simplex
Port wine stain, IC calcifications
Nevus flammeus
Shallow fibrin-coated ulcer w/ mononuclear infiltrate
Aphthous ulcer
Whitish macules w/ hyperpigmented borders, mouth, breasts
Vitiligo = destruction of melanocytes
Hypopigmentation + anesthesia
Leprosy = get skin bx
Velvety pink or whit macules, less pigmentation
Fungal infection
Acanthosis nigricans assoc
GI malignancy, PCOS, DM
Skin tags assoc
DM, pregnancy, crohn’s
Vitiligo, hypotension, dehydration, hyperpigmented areas assoc
Addison’s disease
Tx for human bites
Augmentin or erythromycin + open
Sharp edge, head & neck spot, orange
Subcutaneous nevi
Present at birth, PITS, ecchymoses, subsides w/in 1 day, Hematoma crosses sutures
Caput succedanuem
Few days after birth, no pitting, Hematoma NOT cross sutures = 1 cranial bone, no discoloration
Cephalohematoma –> resorbs on its own
Pulsations on scalp, inc pressure w/ crying
Cranial meningocele
“Ping-pong ball,” rickets –> resolves
craniotabes
Lateral neck cysts
Brachial cleft, cystic hygromas
Anterior edge SCM, base of neck mass
Brachial cleft cyst
Base of neck, large, mushy, ill-defined mass
Cystic hygroma –> CT b4 excision
INC COSTOCHONDRAL JUNCTIONS, craniotabes, sciolosis, pigeon breast, hyperpigment, genu varum
Rickets
Cough, pink eyes, bluish spots in mouth, blanching, erythematous macropapular rash
Measles = live vaccine, supportive, VitA if hospitalized
Cough, coryza, conjunctivitis + High fever and red-brown macropapular rash for 9 days
Measles –> Vit A reduces M&M
Rash face –> extermities, cough, conjuctivitis, white spots on tonsils
Measles
Clustered white lesions in mouth –> rash on forehead –> trunk –> limbs
Measles
Rash starting on face –> chest and limbs, occipital and post. Cervical LAD
Rubella
Congestion, low fever, pink rash on face –> trunk, cervical adenopathy, patchy palate erythema
Rubella
Fever, sore throat –> rash on face/neck –> trunk –> limbs
Rubella
URI –> erythema on face sparing nose, orbits –> lacy pruritic body rash for 1-2wk, resp spread
B-19 “fifths disease”
B19 in sickle cell; pregnancy
aplastic crisis; hydrops fetalis
Fever/URI + rash on cheeks, worse in sun
Erythema infectiosum (5ths) –> aplastic crisis, arthopathy, hydrops
High fever 3d –> red blanching macules, papules on trunk –> limbs, sparing face
Roseola (HHV-6) = supportive tx
High Fever –> rash - trunk –> limbs/head
Roseola (HHV6,7)
Impetigo or pharyngitis –> tiny blanching rash on trunk to limbs
Scarlet fever - late desquamation
Pharyngitis –> neck, axilla, groin rash finely papular erythematous rash blanches, circumoral pallor
Scarlet fever –> PCN V or erythromycin
Sore throat, fever –> 2d later rough raised rash upper trunk –> limbs & tongue
Scarlet fever (strep)
Tx for strep
PCN or cephalosporins or macrolides –> fever free 24hrs = return to work
Fever 5d, B/L conjuctivitis, mucositis, swelling and erythema on palms and soles
Kawasaki - cervical LN >1.5cm
Hx strep + amoxicillin, 103, strawberry tonuge, B/L conjunctivitis, cervical LN 1.5cm
Kawasaki –> Aspirin + IVIG
B/L conjunctivitis, SWOLLEN LIPS, high fever no relief from tylenol
Kawasaki –> Aspirin + IVIG
“Flea bites,” on trunk/limbs + EOSINOPHILS
Erythema toxicum
Scattered erythematous macules, papules, pustles everywhere, No sx
Erythema toxicum neonatorum = ressurance
Vesicular clusters
HSV or VZV –> acyclovir
Targetoid (pale center) papule or plaque on palms–arms–face, Niloksy (-)
Erythema multiforme - follows HSV infection
Sudden symmetric erythematous target lesions
Erythema multiforme (?recent HSV)
Flu-like sx –> erythematous macules –> necrosis/sloughing, involves mucous membranes
Steven-Johnson syndrome –> IVIG
Hx atopic dermatitis + vesicles on erythematous base on face
Eczema herpeticum
Painful subcutaneous skin lesions on anterior leg —> next step?
CXR = Erythema nodosum —> benign or TB, Sarcoid, IBD, Histo
Crops of small tender, erythematous nodules over shins & calves
Erythema induratum = TB
Erythematous rash, Nilosky (+), perioral crusting
Scalded skin syndrome
Fever, irritable –> blistering, exfoliation
Scalded skin syndrome
Tender skin, bullae, large sheets slough after illness
SSSS
Diffuse red macular rash + peeling of palms and soles
TSS (SA)
Recent nasal packing –> rapid hypotension, rash, fever, thrombocytopenia, mouth hyperemia
TSS (tampons, sinusitis, septorhinoplasty, surgical wounds)
Complications of GABHS
PSGN, RF, arthritis, PANDAS = OCD (SSRIs) or tic
Abx do NOT prevent which GABHS complications
PSGN, arthritis
Vesiculopustules on face, arms, crusted golden-yellow, warm, moist climate
Impetigo
Impetigo Tx
Topical mupirocin, oral dicloxacillin, clinda, cephalexin
Tender, erythematous skin w/ distinct border, scalp, face
Eryipelas –> cephalexin, diclox, clinda, bactrim –> IV if fever present
- pyogenes
- –> GN but not rheumatic fever
Erythema, warmth, tenderness w/ INDISTINCT borders
Cellulitits = pyogenes or SA –> cephalexin, zosyn
Unimmunized kids, blue cheeks, febrile
Buccal cellulitis = Hib –> cefuroxime or taxime
Constipation, perianal cellulitis bug
Pyogenes
Pain out of proportion w/ findings, crepitus, bullae
Necrotizing fasciitis –> IV Abx + debridement
Recent trauma, surg, sudden pain, swelling, purple, serosanguineous discharge & skin bullae
Necrotizing fasciitis
S/P laparotomy, fever, hyperglycemia, cloudy-gray discharge, friable tissue, no sensation
Necrotizing surgical infection –> surgery and debridement
Recurrent, eczematous, pruritic, scaling red papules over flexor/extensors surfaces
Atopic dermatitis
Itchy rash face, hands chest –> erosion, scaling, excoriated plaques and papules
Atopic dermatitis
Patchy, fine, white, adherent waxy scales
Sebhorreic dermatitis –> dandruff, anti-fungal, moisturizers
Yellow papules, some scaling/plaques on eyebrows, nose, head better w/ shampoo
Sebhorreic dermatitis –> dandruff, anti-fungal, moisturizers
Sebhorreic dermatitis cause?
Malessezia furfur
Vesicles, erythema in linear pattern, weepy, crusted, edema
Allergic contact dermatitis –> cell-mediated type IV HS
Pruritic papules and vesicles over extensor surfaces
Dermatitis herpetiformis = Celiac (anti-endomysial)
Erythematous papules, vesicles, bullae on butt, extensor surfaces, intense pruritis
Dermatitis herpetiformis —> DAPSONE
anti-endomysial abs
Dermatitis herpetiformis = celiac
Rosy hue w/ telangiectasias, flushing w/ hot drinks, heat, emotion, 30-60 y/o
Rosacea
Sudden blisters, oral blisters/erosions that rupture easily, Ab to desmoglein, ACE inhibitors
Pemphigus vulgaris –> prednisone or MTX –> Aza to get off steroids
Salmon colored patches, silvery scales over extensor surfaces & scalp
Psoriasis
Numerous oval, scaly lesions over back, crinckled, cigarrette paper apperance
Pityriasis rosea
Pale, velvety white/pink, scale w/ scraping, doesn’t tan
Tinea versicolor –> selenium sulfide or ketconazole
Ring lesions w/ scaly border & central clearing
Tinea corporis –> terbinafine or griseofulvin
Pruritic, erythematous, scaly, red ring w/ central clearing, swimming
Tinea corporis –> terbinafine
Recurrent oral ulcers, genital ulcers, anterior uveitis, hyper-pigmented red skin lesions
Behcet syndrome –> steroids but still –> dementia, blindness
Anti-Rho/SSA or Anti-La/SSB Abs
Sjogren syndrome
Women, 50s, dry eyes, mouth, dental caries, dysphagia, B/L submand swelling
Sjogren syndrome
Winter, Spring papules, vesicles on erythematous base –> erosions, different stages
Varicella –> acyclovir shortens if older than 2, given w/in 24hrs
Dx varicella
Tzanck smear or PCR
Varicella vaccination ages
12-18mo + 4-6yrs, live attenuated
Zoster vaccine ages
60
Lesions of all different stages
Chicken Pox
Macropapular rash on trunk, palms and soles, painless chancre
Syphilus —> Benzathine PCN x3
Macules, papules, pustules at same stage
Small pox (Variola)
Vesicular on tongue/lips/mouth, macoluvesicular on hands, feet, butt, groin
Hand-foot-mouth (Coxsackie)
Erythema marginatum, serpiginous macules w/ pale centers, polyarthritis, sydenham corea
Rheumatic fever
Petechial rash –> ecchymoses, fever, N/V, myalgias, shock
Meningococcemia
Maculopapular rash on lower chest + rose spots on abd, diarrhea, HSM
Typhoid fever
Macrocytic anemia w/o hypersegment, low Retic + congenital syndrome (Turner etc)
Diamond-Backfan anemia (congential hypoplastic anemia) –> steroids or transfusion
Bright red plaque, compressible, well-defined borders, 3mo old
Strawberry (capillary) hemangioma
Small bright red papules in adulthood, do not regress
Cherry hemangioma
Lobulated compressible mass on neck, lymph lined by epithelium
Cystic hygromas
Dec growth, inc bone growth, inc ICP, puruitis, irritable, alopecia, sebhorreic lesions, mouth fissures
Vit A excess
Impaired night vision, dry skin, dry eyes, cloudy cornea, hyperkeratosis
Vit A deficiency
Sebhorreic dermatitis, photophobia, cracking lips, mouth, atrophic tongue, pallor, pale
Riboflavin (B2) deficiency
Diarrhea, erythematous rash in sun exposed areas - arms, legs, beefy red tongue
Pellagra –> Niacin (B3)
Niacin –> NAD, NADP, inc w/ corn eating, diarrhea
Pellagra
Abd pain, diarrhea, corn-based diet, difficulty w/ memory, malar rash worse w/ UV
Pellagra (3Ds) - Niacin deficiency - carcinoic, corn, Hartnup, etOH
Flushing, pruritis
Niacin toxicity
Neuropathy, altered mental status
B6 excess
Depression, dermatitis, stomatitis, irritable, NEUROPATHY
B6 deficiency –> inc homocysteine, embolic events
Goat milk deficiency
Folate
Ecchymoses, petechiae, bleeding gums, arthralgias, weakness, depression, coiled hair, joint swelling
Vit C deficiency
Stone, diarrhea, cramps
Vit C excess
Diarrhea, polyuria, polydipsia, calcification
Vit D excess
Phimosis
Can’t retract foreskin
Paraphimosis tx
Tournequet
Balanitis bugs
Candida or GNs
CIs to circumcision
Hypospadias, bleeding, pre-me
1st teeth to develop and when
3-16mo, 1st = lower incisor
Secondary teeth erupt
6-8y/o
Mandibular central incisors erupt early indicates?
Hyperthyroid, Inc GH, precocious puberty
Causes of delayed teeth eruption
Hypothyroid, pituitary, Down
Pitting teeth, brown/gray, white streaks
No fluoride - need more 2-4 y/o
When to supplement Fl-
Breast fed, >6mo, water <0.3ppm
1 caries place and bug
Maxillary; Strep mutans
Teeth avulsions tx
Store in milk, more time = bad prognosis
Acne treatments
- Mild –> benzoyl peroxide –> clinda or erythromycin
- Moderate –> vit A –> oral doxy or minocycline
- Severe –> isotretinoin (hyperlipemia)