Drugs

Question 1

Olanzapine SE

Answer 1

Avoid in DM and obese = weight gain & sedation

Question 2

Risperidone SE

Answer 2

More movement disorders

Question 3

Quetiapine SE

Answer 3

LESS movement disorders

Question 4

Ziprasidone SE

Answer 4

Prolonged QT - avoid w/ conduction defects

Question 5

Clozapine SE

Answer 5

Agranulocytosis = CBC

Question 6

Antipsychotic w/ LEAST weight gain

Answer 6

Aripipazole

Question 7

DOC for trigeminal neuralgia

Answer 7

Carbemazepine –> check CBC

Question 8

DOC for dog and human bite wounds

Answer 8

Augmentin

- PCN allergy = cipro and clinda

Question 9

DOC for chloroquine resistant malaria

Answer 9

Mefloquine (pregnancy) > doxy or atovaquone

Question 10

Malaria drug w/ prominent hemolysis in G6PD deficiency

Answer 10

Chloroquine - only w/o Falciparum in places like Korea

Question 11

HIV drug side effects

1. Kidney stones
2. Pancreatitis
3. Hypersensitivity
4. Lactic acidosis
5. Steven-Johnson
6. Liver failure

Answer 11

1. Indinavir - protease inhibitor
2. Didanosine
3. Abacavir
4. NRTIs
5. NNRTIs
6. Nevirapine

Question 12

Drug for both depression and nicotine addiction and its SE

Answer 12

Bupropion –> SEIZURE

Question 13

Mech for niacin-induced flushing

Answer 13

PG induced vasodilation - aspirin prevents

Question 14

Drug assoc w/ red/orange body fluids

Answer 14

Rifampin

Question 15

Hypothermia inducing psych med

Answer 15

Fluphenazine - inhibits shivering

Question 16

Tx Chancroid

Answer 16

Single 1g PO Azithromycin

Question 17

Isotretinoin SE

Answer 17

*Teratogen
*Suicide
HLD, LFTs

Question 18

Drugs that cause hyperK

Answer 18

BBs
ACE
K+ sparing diuretics - ENaC
Digitalis - Na/K+ pump
Cyclosporine, heparin - block aldo
NSAIDs - dec renal pefusion
Succ - leakage
TMP - blocks Na channel in CD, artificial inc in Cr (GFR same)

Question 19

Drugs that cause cholestasis

Answer 19

Ceftriaxone

Azithro

Question 20

Drug to tx cat-scratch

Answer 20

Azithromycin

Question 21

CI to metformin

Answer 21

Cr >1.5 men –> RF & lactic acidosis

Question 22

DM med SE = weight gain and hypoglycemia

Answer 22

Sulfonylureas (glipizide)

Question 23

DM med SE = CHF, bladder cancer, fx

Answer 23

TZDs (pioglitazone)

Question 24

DM med if weight loss desired

Answer 24

GLP-1 agonist (exanitide)

- acute pancreatitis

Question 25

HbA1c level to add insulin to metformin

Answer 25

> 8.5

Question 26

SE of amiodarone

Answer 26

Pulmonary
Hypothyroid > hyper
LFTs
Corneal deposits - no need to stop drug
Blue-gray skin on face

Question 27

Plan B drug

Answer 27

levonorgestrel - up to 120hrs

Question 28

Cyclosorine mech & SE

Answer 28

Inhibits IL-2

Gingival hypertrophy
SCC
Hyperglycemia
Tremor, akinetic mutism
HTN
Nephrotoxic --> gout, hyperK

Question 29

Azathioprine mech & SE

Answer 29

Inhibits purine synthesis

Diarrhea
Leukopenia
Hepatotoxicity

Question 30

Mycophenolate mech & SE

Answer 30

Inhibits IMPDH in purine synthesis

MARROW suppression

Question 31

Tamoxifen SE

Answer 31

ENDOMETRIAL CA

DVT

Question 32

Tx for enterobius

Answer 32

Albendazole

Question 33

Risk w/ lidocaine w/ ACS

Answer 33

Inc ASYSTOLE

Question 34

Tx of Legionella

Answer 34

Levo

Azithro

Question 35

Gram + partially acid-fast branching rods tx?

Answer 35

Nocardia = TMP-SMX

Question 36

Tx mucormycosis

Answer 36

Debridement + IV amphotericin B

Question 37

Efavirenz SE

Answer 37

Insomnia, bizarre dreams

Question 38

Tx severe hypertriglyceridemia or xanthomas

Answer 38

Fibrates

Question 39

Mech of glipizide (sulfonylurea)

Answer 39

Inc endogenous insulin production

Question 40

Prolongs QT

Answer 40

Procainamide
Amiodarone
Sotaolol
Propenafone