E4 Rheumatoid Arthritis Flashcards
2 major cell types associated with pannus
T lymphocytes
macrophages
major cell type associated with synovial fluid
neutrophils
what is the main diagnostic thing we look for in RA?
how many joints are involved
pts are diagnosed with RA if there is a score of __ or more
6
3 most common joints involved in rA
hands
wrists
feet
give a few of the extra articular manifestations of RA
nodules
vasculitis
pulmonary
cardiac
feltys
ocular
when are rheumatoid nodules more common
in erosive disease
how do i know when to treat nodules in RA?
if pt has symptoms
inflammation of small, superficial blood vessels
vasculitis
what serious thing can vasculitis lead to?
necrosis and stasis ulcers
what two things can RA cause in the pulmonary system
pleural effusions
pulmonary fibrosis
what can RA cause in the ocular system?
sjogrens syndrome and itchy dry eyes with inflammation
3 things RA can cause in cardiac system
pericarditis
conduction abnormalities
rare: myocarditis
what tf is feltys syndrome
inflamed spleen and presence of neutropenia
T or F:
RA can also cause thrombocytosis and renal disease
false, renal disease is associated with treatment not RA
what is ESR?
erythrocyte sedimentation rate (lab indicator for RA)
normal ESR
0-20 mm/hr
is ESR decreased or increased in RA?
increased so above 20
normal CRP
0-0.5 (diagnostic criteria for RA)
a CRP > ? can indicate bacterial infection
10
what is RF?
rheumatoid factor, it is an antibody specific for IgM
T or F:
Not all pts with RA diagnosis are RF+
tru
what is CCP/ACPA
auto antibody presence test (this is a new diagnostic method)
what is ANA?
antinuclear antibodies
