E2 Supp Care II

Question 1

list the shit for OPQRSTU

Answer 1

onset
provokes
quality
radiate
severe
time
understanding

Question 2

which opioid has the most “familiarity” in cancer

Answer 2

morphine

Question 3

morphine metabolized where

Answer 3

liver

Question 4

morphine metabolites excreted where

Answer 4

kidney

Question 5

hydromorphone metabolized where

Answer 5

liver

Question 6

t or f:
both morphine and hydromorphone should be used with caution in liver dysfxn

Answer 6

true

Question 7

what metabolizes oxycodone?

Answer 7

CYP2D6

Question 8

Use oxycodone with caution in pts with?

Answer 8

liver dysfxn

Question 9

which opioids appears to be safe in renal dysfxn?

Answer 9

fentanyl
methadone

Question 10

which opioid is a good alternative for pts with head/neck/esophageal cancer who may not be able to maintain adequate PO intake?

Answer 10

fentanyl

Question 11

which opioid has REMS protocol

Answer 11

fentanyl

Question 12

which opioid to use in pts with true morphine allergy

Answer 12

methadone

Question 13

opioid to use in pts with neuropathic pain

Answer 13

methadone

Question 14

methadone metabolites excreted where?

Answer 14

urine and feces

Question 15

Methadone not advised in what dysfxn

Answer 15

liver

Question 16

which opioid has risk of QTC prolongation

Answer 16

methadone

Question 17

what is something you always add when opioid tx is initiated

Answer 17

bowel regimen (mild stim lax +/- stool softener

Question 18

4 common tox of opioids

Answer 18

constipation
sedation
N/V
pruritus

Question 19

opioid common tox tx:
sedation

Answer 19

tolerance within few days
hold sedatives/anxiolytics
reduce dose

Question 20

opioid common tox tx:
N/V

Answer 20

change opioid
add scheduled anti-emesis tx

Question 21

Pruritus is most often seen with _________ administration

Answer 21

morphine

Question 22

what common opioid toxicity are we able to give a low dose of naloxone for?

Answer 22

respiratory depression

Question 23

Patient Controlled Analgesia (PCA):
Use caution with continuous basal dosing initially for _________ _______ patients

Answer 23

opioid naïve

Question 24

what is the celiac plexus

Answer 24

a group of nerves that supply organs in the abdomen

Question 25

go look at slide 34 and try to see what you can gather from step 3

Answer 25

okay i will do this, cole

Question 26

Used in patients who are refractory to other opioid therapy or increased toxicities (not a drug)

Answer 26

intrathecal pain pumps

Question 27

T or F:
Patients generally have more toxicities from intrathecal pain pumps than benefit from traditional opioid therapy

Answer 27

true

Question 28

RECIST

Answer 28

Response
Evaluation
Criteria
In
Solid
Tumors

Question 29

RECIST Criteria:
Disappearance of all target lesions
A. Complete response (CR)
B. Partial response (PR)
C. Progressive disease (PD)
D. Stable disease (SD)

Answer 29

A

Question 30

RECIST Criteria:
30% decrease in the sum of the longest diameter of target lesions
A. Complete response (CR)
B. Partial response (PR)
C. Progressive disease (PD)
D. Stable disease (SD)

Answer 30

B

Question 31

RECIST Criteria:
20% increase in the sum of the longest diameter of target lesions
A. Complete response (CR)
B. Partial response (PR)
C. Progressive disease (PD)
D. Stable disease (SD)

Answer 31

C

Question 32

RECIST Criteria:
Small changes that don’t meet above criteria
A. Complete response (CR)
B. Partial response (PR)
C. Progressive disease (PD)
D. Stable disease (SD)

Answer 32

D