Drug classifications Flashcards
what is a psychoactive drug
Substances that impact the nervous system to alter a person’s mood, per-ceptions, or level of consciousness (as
T: Substances that impact the nervous system to alter a person’s mood, per-ceptions, or level of consciousness (as
psychoactive drug
4 names a drug can have
a chemical name, a generic name, and a trade name and street name
what makes up the generic name
the generic name was derived by combining parts of the chemical name, and these names are still in use.
what does it mean to use a stem in a generic name
The stem is usually the last part of the generic name, although it could be at the beginning or in the middle. (For example, oxetine is a stem that indicates an antidepressant drug. Thus, if you see the name fluoxetine or duloxetine)
Initially, the generic name was derived by …
combining parts of the chemical name
Most scientific journals and textbooks published in North America (including this book) use what drug classification for their generic names
United States Adopted Names (USAN).
SKF 10,047. what do the letters and numbers in this stand for
The letters refer to the drug company (in this case, Smith, Kline, and French), and the numbers are a unique code for the drug.
review table 1.1 generic names stems
…
what are the 3 steps in the Process
of Pharmaceutical Drug Development
preclinical testing
clinical testing
off label use
what are the 2 methods to conduct preclinical testing
Some of this research is conducted in vitro (in cells in a test tube or culture dish) and some in vivo (in experimental animals, usually rats or mice).
what are the 4 phases of clinical testing
Phase I: Pharmacokinetic and Safety Testing.
Phase II: Small-Scale effectiveness Testing
Phase III: Large-Scale effectiveness Testing. (goes public)
Phase IV: Postmarketing Studies.
T: that the drug has other potential benefits and prescribe it to treat other disorders
off label use
what name is the drug sold as
trade name
By the time the drug is fully developed and granted approval for sale, … of patent remain while the drug is on the market.
about 7 to 12 years
one drug has one trade name
f can have many labelled and sold by different companies
Trade names can be distinguished from generic names how?
because their first letter is capitalized.
may contain a number of other ingredients—fillers, coloring agents, binding agents, fla-vors, preservatives, and coatings—T:
collectively referred to as excipients.
a drug with the same active ingredient that dissolves slowly or fast are = drugs
f may change how effective it is
The excipients and the active ingredient are combined in a particular way, and this is known as the drug’s ..
formulation
ecstacy is what kind of name
street name
All of modern science uses the metric system and drug doses are nearly always stated in…
milligrams (mg)
research done with rats and mice often uses doses that appear excessive in human terms. why?
need more due to fast metabolisms
what does the horizontal and vertical axis on a DEC or DRCrepresent
The effect of this range of doses is plotted on a graph, with the dose indicated on the horizontal axis and the effect on the vertical axis.
