Chapter 4 Flashcards
neurons always look the same
f Dif shapes and sizes
A protein is a chain of fairly simple building-block molecules called …
amino acids
how many of the 22 amino acids must we ingest in food
8
what is a node of ranvier
Uninsulated sections of the axon
REVIEW FIGURE 4.1
?
what is the charge difference inside and outside the neuron
The inside of the neuron is slightly negative relative to the outside.
why is it important that neutrons are slightly negative in cell
This potential difference results from an uneven distribution of ions between the inside and outside of a cell.
what ionized molecules make for the resting potential of a cell
K + and Na +
Cl-
To understand the resting potential, we need to under-stand two things: …2
(a) The membrane potential is a relative potential—that is, we are always comparing the inside to the outside of the membrane; and (b) the outside of the membrane is always considered equal to zero.
of K, A, Cl and Na which are more inside or outside the cell
more K and A inside cell
3 passive processes?
diffusion, electrostatic charge and differential permiability
what is differential permeability
The only way ions can move into and out of the cell is through thousands of these specialized protein channels called ionophores or ion channels. These proteins are often a target of behav-iorally active drugs.
K+ and Cl–ions cross the cell membrane by easily passing through these channels, but tend to maintain their relative concentrations ..why?
inside and outside the cell (respectively) because the forces of diffusion and electrostatic charge off-set each other,
does A ever move in or out of cell
no too big
passively there is more Na inside the cell
t active t keeps it out (3 na out for every 1 k in
The resting potential of a neuron describes the …
distribution of ions in the absence of stimulation, but this membrane potential can vary substantially in response to a variety of stimuli.
When the membrane potential becomes less negative (i.e., moves toward zero and positive numbers), it is called…
depolarization
When the membrane potential becomes more negative (i.e., moves further away from zero), it is called ….
hyperpolarization.
what’s a cells normal resting potential
-70 mV
if the neuron is depolarized to about −55 mV, called the …, the entire resting potential and the processes that maintain it break down.
threshold
why does breakdown occur at threshold
because of special gated ion channels that are sensitive to the number of positive charges inside the cell. When the potential difference is reduced beyond the threshold, these voltage-gated ion channels open, allowing the free flow of ions across the membrane.
At this point, Na+ channels close, mark-ing the end of the … of the action potential. K+ channels remain open, and the efflux (outflow) of K+ continues; this is called the … phase of the action potential.
rising phase
repolarization
This breakdown and restoration of the resting poten-tial is known as an …., and it occurs very quickly.
action potential
how many ap can occur per second
thousands