Chapter 1 Flashcards
how do we define drugs traditionally
substance that alters physiology of the body
is vit c a drug?
if consumed in bit form not if in orange
what is a psychoactive drug
Substances that impact the nervous system to alter a person’s mood, per-ceptions, or level of consciousness (as caffeine does) are often referred to as psychoactive drugs.
Substances that impact the nervous system to alter a person’s mood, per-ceptions, or level of consciousness (as caffeine does) are often referred to as …
psychoactive drugs
when gas is inhaled in the workplace what do we refer to it as
enviro toxin
Pharmaceutical drugs have at least three names what are they
chemical, trade name and generic name
7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1, 4-benzodiazepin-2-one what can a chemist tell by this name
how the molecule is made up (joints of the drug molecule)
are chemical drug names always the same
the same drug will have different chemical names if different conventions are used.
how was the generic name made up initially
combining parts of the chemical name
what is the trade name
different formulations of the same drug (the drug in different states)
what is the street name for MDMA
ecstacy
All of modern science uses the … system and drug doses are nearly always stated in …
metric, milligrams
A milligram is … of a gram
1/1,000
what effects a drugs effects on the body? the amount fo the drug?
no the concentration = mg per kg
why are drug studies not always accurate
because Dif metabolisms = Dif concentrations of drug in the body = higher dose in animals
what is a dose–effect curve (DEC) or a dose–response curve (DRC)?
a graph that administers Dif dosages of drug (from so low you can hardly tell to so high nothing more is happening)
T: The range should include a dose so low that there is no detectable effect, a dose so high that increases in dose have no further effect, and a number of doses in between
dose–effect curve (DEC)
a small change in … doses will have a large effect
low not high
???scale on the horizontal axis is graduated loga-rithmically allows a wide range of doses to be reported and permits greater precision at the low end of the dosage range.
?
what’s on the vertical axis?
a continuous measure or a binary measure
Binary drug effects are handled by …
working with
groups of subjects.
4 types of names? do you know the difference?
trade name, street name, generic name and chemical name
what are 2 common ways of describing dosage response curves?
LD and ED50
what is ED50?
the median effective dose (effecting in 50% of populous)