Donor Requirements And Intervals Flashcards
Age
16 years old
Or applicable state law
Blood pressure
Systolic: 90-180
Diastolic: 50-100
Weight
110 lbs
Temperature
< 37.5 C (99.5 F)
Pulse
50-100
Skin examination
Free of infection, inflammation, and evidence is drug use
Mild skin issues only a problem if they interfere with decontamination process
Female Hgb/Hct
12.5 g/dL
>38%
Male Hgb/Hct
13.0 g/dL
>39%
Hgb/Hct determination method
Anything but earlobe capillary collection
Except for double RBC donation- must be quantitative measurement (no copper sulfate method)
Autologous donation criteria
Hgb > 11.0 g/dL
Collection > 72 hrs before surgery/use
Physician order for collection
Donation interval:
While blood
8 weeks
Donation interval:
2 unit RBC
16 weeks
Donation interval:
Infrequent plasmapheresis
4 weeks
Donation interval:
Frequent plasmapheresis
2 days (not >2 in 7 days)
Donation interval:
Plateletpheresis
2 days for single
7 days for double/triple
Donation interval:
Cytapheresis (granulocytes)
2 days (no more than 2 times in 7 days) Not > 24 in rolling 12 months
Volume of blood permitted to be collected
10.5 mL/kg of donor weight
Post donation donor care
Local pressure applied to phlebotomy site while arm is elevated until hemostasis is achieved
Donor given post donation instructions and observed for signs of adverse reactions
Needle related donor injuries (in order of frequency)
Bruise/hematoma
Local nerve injury
Arterial puncture
Systemic donation adverse reactions
Vasovagal
Citrate toxicity
Allergic
Minimum platelet count for platelet pheresis donation
150,000
Deferral for apheresis platelet donation after whole blood donation
8 weeks
Unless extracorporeal volume of instrument is <100 ml
Whole blood units unsuitable for platelet or plasma use (2)
Collection time >15-20 min
Low volume unit
Frequent plasma donation donor considerations
No deferral for malaria risk
Serum protein 6-9 g/dL
Electrophoresis every 4 months with normal protein fractionation
Physical exam once a year
Maximum plasma loss w/in 12 months
110-175 lb
12 L
Max plasma loss w/in 12 months
>175 lb
14.4 L
Therapeutic phlebotomy indications (9)
Polycythemia Vera Erythropoietin receptor mutations High oxygen affinity Hb mutations Polycythemia due to high altitude residency Cyanotic congenital heart disease Respiratory disease Erythropoietin producing neoplasms Porphyria cutanea tarda (most common) Hereditary hemochromotosis
Vasovagal risk factors (5)
Young age Low weight First time donation Inattentive phlebotomist Epidemic fainting
Nerve injury risk factors (3)
Hematoma formation
Female
Younger than average age
Usually presents on day of donation
Time is major treatment option
Arterial puncture characteristics (4)
Severe or unusual pain
Rapid filling of bag
Bright red blood
Movement of needle with heartbeat
Low volume unit collection amount
300-404 ml in a 450ml bag
333-449 ml in a 500ml bag
Autologous donation: acute normovolemic hemodilution
Replacement fluids and ratio
Crystalloid 3:1
Colloid 1:1
Autologous donation: acute normovolemic hemodilution
Blood storage
Room temp
8 hrs from start of collection
Autologous donation: acute normovolemic hemodilution
Infusion order
Infused in reverse order of collection
Lower concentration of RBCs infused first
Autologous donation: acute normovolemic hemodilution
Collection/labeling
Collected into standard blood bags containing anticoagulant
Labeled with patient name, MR #, date and time of collection and ‘for autologous use only’
Autologous donation: acute normovolemic hemodilution
Patient selection criteria
Likelihood of transfusion >10% Preop Hgb >12 g/dL No significant coronary artery, pulmonary, renal, or liver disease No severe hypertension Absence of infection/risk of bacteremia
Time frame of donor eligibility determination
Must be established on the day before collection
24 hrs to clarify any information in the screening
Facilities have how long to notify donors of test results that would defer them from further donation
8 weeks
