DNA Chapter 7.2 Flashcards

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1
Q

the 2 types of nucleic acids

A

dna ( deoxyribonucleic acid)

Rna ( ribonucleic acid)

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2
Q

Nucleotides

A

the building blocks of nucleic acid

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3
Q

structure of a nucleotide

A

sugar ( deoxyribose or ribose)
a phosphate group
nitrogenous base
They always have the the same sugars and phosphate but have one of the different nitrogenous bases.

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4
Q

DNA double helix resembles a twisted ladder or staircase

A

Railings —–( sugar phosphate backbone)
Alternating units of
deoxyribose and phosphate joined with covalent bonds.

The stairs——-A-T, G-C base pairs joined by hydrogen bonds.

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5
Q

how are the Railings —–( sugar/ phosphate backbone)

Alternating units of deoxyribose and phosphate

A

with covalent bonds

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6
Q

How are the The stairs——-A-T, G-C base pairs joined

A

with hydrogen bonds

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7
Q

A-T and G-C arise from their chemical structure

A

A (adenine) and G (guanine) are purines
T ( thymine) and C ( cytosine) are pyrimidines

A———————–T

G———————-C

(PURINES) (PYRIMIDINES)

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8
Q

Purines

A

bases with a double ring structure( Adenine

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9
Q

pyrimidines

A

bases with a single ring structure

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10
Q

A-T and G-C are the same width because

A

Each pair includes a purine and a pyrimidine

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11
Q

Explain the pairings of the bases

A

A-T and G-C
Each pair has equal amounts of each base

The pairs have the same width because each contain a purine and a pyrimadine

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12
Q

The two strands of DNA are COMPLEMENTARY because

A

The sequence of each strand defines the sequence of the other

( A on one strand means a T on the other)
( G on one strand means a C on the other)

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13
Q

Why is complementary base important

A

It is the basis of gene function

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14
Q

How are the two strand physically arranged

A

. They go in opposite directions

The two strands are parallel but tail to head ( anti parallel)

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15
Q

The designation of the opposite end of the double helix

A
3 prime ( ending with a 3' carbon)
5 prime ( ending with a 5'carbon)
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16
Q

What are the components of DNA and its three-dimensional structure

A

The components of a DNA molecule are nucleotides. These are composed of a deoxyribose sugar bonded to a phosphate and a nucleotide base (adenine, thymine, cytosine, or guanine). The three-dimensional structure of DNA is a double helix, which resembles a twisted ladder.

17
Q

What evidence enabled Watson and Crick to decipher the structure of DNA

A

The evidence included Rosalind Franklin’s X-ray diffraction photo of a crystal of DNA, plus Erwin Chargaff’s work that showed that DNA contains equal amounts of adenine and thymine and equal amounts of cytosine and guanine.

18
Q

Identify the 3′ and 5′ ends of a DNA strand

A

The 5’ end has the 5th numbered carbon in deoxyribose facing out and leading with a phosphate group attached, and the 3’ end has the 3rd numbered carbon leading with no phosphate, just the OH attached to the carbon.
3’ and 5’ are numbersmthat chemist assign to carbon atoms in deoxyribose