DJD OA GAL Flashcards

1
Q

DEGENERATIVE JOINT DISEASE

A

Diarthroidal joints

Destruction of articular cartilage

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2
Q

CLINICAL SIGNS OF DJD

A

Joint effusion
Lameness
Heat
Pain on flexion

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3
Q

No direct correlation between pathological changes and clinical significance

A

No direct correlation between pathological changes and clinical significance

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4
Q

TYPE 1 DJD

A

Young race horses - 1o TB
Highly mobile joints
Acute inflammation
Capsulitis -synovitis

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5
Q

TYPE 2 DJD

A

Older horses
Insidious onset
High load - low motion joints
Common sites: DIT, TMT, & PIP joints

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6
Q

GROSS LESIONS OF DJD

A

Softening & yellowing of cartilage
Fibrillation
Erosion with Subchondral sclerosis +/- eburnation
Grooving of Subchondral bone

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7
Q

DIAGNOSIS OF DJD CHRONIC

A
Enlarged joint
Decreased range of motion
\+/- Acute signs
Radiographs
Synovial fluid analysis - DOES NOT MATTER
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8
Q

PRINCIPLES OF THERAPY

A

Prevent or treat the primary problem
Treat the active soft tissue disease
Treat the articular cartilage loss or degeneration
Rehabilitatio

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9
Q

HYALURONIC ACID

A

Improved binding of proteoglycan subunits
Improved lubrication of soft tissues
Establishes a barrier to further effusion
Scavenges free radicals
Primary use - synovitis

Significance of Molecular Weight

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10
Q

ADEQUANPSGAG

A

Polysulfated glycosaminoglycan
Similar to mucopolysaccharides of cartilage matrix
Administered IA or IM
Reactions assoc. with IA use

Binds to damaged cartilage
Stimulates production of collagen matrix and proteoglycans

לא נשתמש בשילוב של שניהם
או HA GAG

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11
Q

ADVANTAGES OF CORTICOSTEROIDS

A
Very good anti-inflammatory
Stabilizes synovial lining cells
Protects synovial vasculature
Reduces edema
שימוש בבתאמתאזון
טריאמצנולון
מתאימים למפרקים עם תנועה רבה

לעומת דפומדרול
למרקים מועטי תנועה

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12
Q

nsaids

A

בנאמין
פנילבוטאזון
חומרים חדשים: קטופרופן

DMSO:
נוגד דלקת מקומי ונטרול רדיקלים מחמצנים

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13
Q

שטיפת מפרק

A

לא משמעותי בAO

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14
Q

פיזיותרפיה

A

חלק מהשיקום
יומיים ראשונים בקרח
ואחר כך טיפול בחום להפגת הבצקת

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15
Q

TYPE 3 DJD

A

שחיקה של הסחוס משמעות לא ברורה

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16
Q

TYPE 4 DJD

A

OA
משני לבעיה ראשונית אחרת:
ספסיס DOD שברים טראומהלוקסציה

17
Q

רקע כללי

A

בכל החיות ובמיוחד בסוסים
נובע מהרס של סחוס מפרקי
ביטוי קליני בנפיחות צליעה חום כאבים בפלקסיה

נזק לסחוס
פיברילציה- שערות קטנות בסחוס