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Pharma > Diuretics > Flashcards

Diuretics Flashcards

1
Q

Site of Carbonic Anhydrase Inhibitors

A

Proximal Convoluted Tubule

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2
Q

Carbonic Anhydrase Drug

A

“Zolamides”

Acetazolamide

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3
Q

Use of Acetazolamide

A

DiarrheaGlaucoma
Edema with Alkaslosis
Mountain Sickness

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4
Q

SE Acetazolamide

A

Hyperchloremic metabolic acidosis

Hepatic encephalopathy

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5
Q

NAGMA

A 
HARD UP
Hyperalimentation
Acetazolamide
RTA
Diarrhea
Ureteral diversion
Pancreatic Fistula
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6
Q

Site of action Loop Diretics

A

Thick Ascending Loop of Henle

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7
Q

Decrease efficacy of Loop Diuretics

A

NSAID

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8
Q

Prototype Loop Diuretic

A

Furosemide

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9
Q

Loop Diuretics inhibit

A

Na/K/2Cl transporter

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10
Q

Uses Loop Diuretic

A

Anion Overdose, Hypercalcemia

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11
Q

SE Loop Diuretic

A

Hypokalemic metabolic alkalosis

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12
Q

Synergistic ototoxicity with Furosemide

A

Aminoglycosides

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13
Q

Furosemide Toxicity

A 
OH DANG
Ototoxicity
Hypokalemia
Dehydration
Sulfa Reaction
Nephritis
Gout
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14
Q

Site of Thiazide Diuretics

A

DCT - Na/Cl transporter

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15
Q

Diuretic for Hypercalciuria and Nephrogenic DI

A

Thiazides - Hydroxychlorothiazide

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16
Q

Thiazide Toxicity

A 
Hyper GLUC
Hyper Glycemia
Hyper Lipidemia
Hyper Uricemia
Hyper Calcemia
17
Q

Steroid inhibitors of cytoplasmic aldosterone receptor in cortical collecting ducts

A

Spirinolactone

18
Q

K Sparing diuretics

A 
K STAE
Spirinolactone
Triamterene
Amiloride
Epleronone
19
Q

Gynecomastia drugs

A 
Spirinolactone
Digoxin
Cimetidine
Alcohol
Ketoconazole
20
Q

Potassium Sparing, Na blocker
Inhibits ENaC
Used for Hypokalemia

A

Amiloride

21
Q

Retains Water in the Tubule

A

Osmotic Diuretics, Mannitol

22
Q

For Rhabdomyolysis, Increase Intracranial pressure, Acute Glaucoma

A

Osmotic Diuretics - Mannitol

23
Q

AE of Mannitol

A

Transient volume expansion

24
Q

Site of ADH action

A

Medullary Collecting Ducts

25
Q

Agonist V1 and V2

Insertion of Aquaporin Water Channels in CD

A

Vasopressin

26
Q

For central diabetes insipidus, Nocturnal enuresis, Hemophilia and vWD Disease

A

Vasopressin

27
Q

Increases Factor VIII

A

Vasopressin

28
Q

ADH not given in pregnancy as it inc uterine pressure

A

Telopressin

29
Q

V1 AND V2 Antagonist

A

Conivaptan

30
Q

For SIADH and Hyponatremia

A

Conivaptan

31
Q

SE of Conivaptan

A

Nephrogenic DI

Bone and Teeth Abnormalities

32
Q

Dual endothelin receptor agonist for pulmonary HPN

A

Bosentan

33
Q

Acts in metab of lipid and CHO, has protective effects in cardiac and endothelial dysfunction

A

L Carnitine

34
Q

Sympatholytic anti HPN, acts as a A1 antagonist and 5HT1A agonist

A

Urapidil

35
Q

Stabilized cell membranes and reduces free radicals

A

Citicoline

36
Q

B2 adrenoceptor agonist, tx of premature labor and Raynauds

A

Isoxuprine

Pharma (20 decks)

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