Adrenergic pharmacology + Sympathomimetics Flashcards
Inhibits Tyrosine to DOPA
Metryrosine
Vesicular Transport (Storage) inhibited by
Reserpine
Release by entry of Ca triggers among SNARE Proteins
inhibited by: Guanethedine
promoted by: Amphetamine and Tyramine
Diffusion and reuptake via NET and DAT is inhibited by
TCA and Cocaine
metabolism b MAO and COMT into metanephrines and VMA inhibited by
MAOi and COMTi
Synthesis Inhibition
Metyrosine
Storage Inhibition
Reserpine
Release Inhibition
Guanethedine
Metabolism Inhibition
MAOi and COMTi
Reuptake Inhibition
Cocaine, TCA
Contriction
a1
Dec NT release
a2
Inc HR, Inc Renin
B1
Relaxation
B2
Lipolysis
B3
Renal Vasodilation
D1
Inhibits Adeyltae Cyclase
D2
Activates a and B receptors
B2 - Bronchodilation
Epinephrine
Activates a and B receptors
(-) Bronchodilation
Norepinephrine
DOC Cardiac Arrest
Epinephrine