Adrenergic pharmacology + Sympathomimetics Flashcards

1
Q

Inhibits Tyrosine to DOPA

A

Metryrosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Vesicular Transport (Storage) inhibited by

A

Reserpine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Release by entry of Ca triggers among SNARE Proteins

A

inhibited by: Guanethedine

promoted by: Amphetamine and Tyramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diffusion and reuptake via NET and DAT is inhibited by

A

TCA and Cocaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

metabolism b MAO and COMT into metanephrines and VMA inhibited by

A

MAOi and COMTi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Synthesis Inhibition

A

Metyrosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Storage Inhibition

A

Reserpine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Release Inhibition

A

Guanethedine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Metabolism Inhibition

A

MAOi and COMTi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Reuptake Inhibition

A

Cocaine, TCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Contriction

A

a1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dec NT release

A

a2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Inc HR, Inc Renin

A

B1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Relaxation

A

B2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lipolysis

A

B3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Renal Vasodilation

A

D1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Inhibits Adeyltae Cyclase

A

D2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Activates a and B receptors

B2 - Bronchodilation

A

Epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Activates a and B receptors

(-) Bronchodilation

A

Norepinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

DOC Cardiac Arrest

A

Epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

DOC Anaphylaxis

A

Epinephrine - In the pines arrest Ana

22
Q

Neurogenic and Cardiogenic Shock (Last Resort)

A

Norepinephrine

23
Q

SE: Norepinephrine

A

Extreme Vasospasm

24
Q

Reflex Bradycardia

A

Norepinephrine

25
Q

Cardiogenic Shock and Heart Failure

A

Dopamine

26
Q

binds to a1,b1,D1 receptors

A

Dopamine

27
Q

Low dose dopamine (1-5)

A

D1

28
Q

Medium dose (5-15)

A

B1

29
Q

High dose (>15)

A

a1

30
Q

Sympathomimetic for Asthma

A

Isoproterenol - Adrenergic (Ipratropium - Muscarinic)

31
Q

a1 agonist

A

Phenylephrine - a1 - vasoconstriction, inc BP

32
Q

a1, nasal decongestant, drug induced hypotension, mydriasis without cycloplegia

A

Phenylephrine

33
Q

SE Phenylephrine

A

Rebound nasal decongestion

34
Q

DOC for a1 agonist overdose

A

Phentolamine

35
Q

a1 avoided in 1st trimester possible risk of gastroschisis

A

Pseudophedrine

36
Q

a2 agonists

A

Methydopa
Clonidine
Apraclonidine

37
Q

a2 agonist Hypertension, Cancer, Opioid Pain

A

Clonidine

38
Q

a2 agonist, Preeclampsia, Gestational HPN

A

Methyldopa

39
Q

a2 agonist sedative - Conscious sedation

A

Dexmedetomidine

40
Q

a2 agonist muscle relaxant

A

Tizanidine

41
Q

a2 for glaucoma

A

Apraclonidine

42
Q

Rhinitis medicamentosa

A

SE of Phenyleprine

43
Q

Antidote for a2 toxicity

A

Phentolamine

44
Q

Preeclamptic, -> Methydopa

A

Hemolytic anemia, + Coombs

45
Q

b1 agonist
Heart Failure
Cardiogenic shock

A

Dobutamine

46
Q

Cardiac Stress testing

A

Dobutamine

47
Q

SE Eosinophilic Myocarditis

A

Dobutamine

48
Q

B2 agonist

Acute Asthma - DOC

A

Salbutamol

49
Q

B2 agonist

Tocolytic

A

Terbutaline

50
Q

Vasodilator in Raynaud’s

Maternal Pulmonary edema

A

Isoxuprine

51
Q

Nasal vasoconstrictor
Appetite Suppressant
SE: Hemorrhagic stroke

A

Phenypropanolamine