Asthma Drugs Flashcards

1
Q

DOC Acute asthma attacks

For Hyperkalemia

A

Albuterol/ Salbutamol

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2
Q

B2 Selective Agonist (Short Acting)
Causes Bronchodilation
May precipitate arrhythmias and Tachycardia

A

Albuterol/ Salbutamol

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3
Q

B2 Selective (Long Acting)
Used as Asthma Prophylaxis
Potentiates corticosteroid action
Increases Asthma mortality when used alone

A

Salmeterol

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4
Q

Ultra Long acting LABAs

A

Vilanterol
Indicaterol
Olodaterol

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5
Q

DOC for COPD

A

Ipratropium - less toxic than B blockers in COPD

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6
Q

Muscarinic receptor antagonist
Blocks muscarinic receptors in bronchial smooth muscles
Prevents vagal stimulated bronchoconstriction

A

Ipratropium

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7
Q

Longer DOA than Ipratropium

A

Tiotropium
Umeclindum

Tio Uncle

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8
Q

Mexthylxantine

A

“Phylline”

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9
Q

Phosphodiesterase inhibition
Adenosine receptor antagonist
For Nocturnal Asthma Attacks

A

Theophylline

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10
Q

Intermittent claudication

A

Pentoxyfylline

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11
Q

Antidote for Methylxanthine overdose

A

Beta blockers

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12
Q

Causes bronchodilation and increase strength of Diaphragm

A

Methylxanthine - Theophylline

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13
Q

Mast Cell Stabilizer
For asthma prophylaxis
No Bronchodilation

A

Cromolyn

Cromwells massive props has no broncos

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14
Q

Drug of choice for Asthma Prophylaxis

A

Fluticasone

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15
Q

Inhibits phospholipase A2
Asthma prophylaxis DOC
SE: Oropharyngeal candidiasis
Increases responsiveness of B receptors in airway

A

Fluticasone - Corticosteroid

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16
Q

For Status Asthmaticus

A

Prednisolone or Hydrocortisone

17
Q

Lowest steroid Toxicity

A

Ciclesonide

18
Q

Inhibits of 5 lipoxygenase
Asthma Prophylaxis
Exercise, Antigen, Aspirin induced bronchospasm
SE: Flu like symptoms, Hepatitis, Elev. liver enzymes
No bronchodilator action, not for acute BA attack

A

Zileuton - Leukotriene synthesis inhibitor

19
Q

Blocks cysteinyl leukotriene RECEPTORS
Asthma Prophylaxis
Exercise, Antigen, Aspirin induced bronchospasm
SE: Neuropsychiatric, Churg- Strauss Syndrome
No bronchodilator action, not for acute BA attack

A

Montelukast - Leukotriene receptor antagoist

20
Q

Anti IgE antibody
Prophylaxis of severe, REFRACTORY ASTHMA
SE: Idiopathic severe thrombocytopenia

A

Omalizumab