Antihypertensives Flashcards

1
Q

Target BP no comorbidities

A

140/90

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2
Q

Target BP DM and CKD

A

130/80

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3
Q

Antihypertensive agents for pregnant women

A

Nifedipine
Methyldopa
Labetalol

Knife in a Methlab

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4
Q

First DOC for Pregnant HPNives

A

Methydopa

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5
Q

2nd line DOC for pregnant HPNives

A

Labetalol

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6
Q

Effective as monotherapy or as add on with methydopa in chronic hypertension in pregnant women

A

Hydralazine

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7
Q

Hypertensives not recommended for pregnancy

A

ACEi or ARBs

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8
Q

1st Line Antihypertensives

A

Thiazide Diuretics

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9
Q

Inhibirs Na/Cl treansporter in the DCT

A

Thiazide diuretics

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10
Q

Thiazide that crosses the cord blood and passes the placenta

A

Metolazone

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11
Q

Antihypertensive diuretic that is also used for Nephrogenic Diabetes Insipidus

A

Thiazide Diuretics

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12
Q

Inhibits Na/K/2Cl transporter

A

Loop Diuretics - Furosemide

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13
Q

Antihypertensive diuretic also used for Anion overdose

A

Loop Diuretic

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14
Q

Diuretic with AE of Hypocalcemia

A

Loop Diuretic

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15
Q

Loop diuretic that can be given to sulfur allergy

A

Ethacrynic acid

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16
Q

AE:
Hyoicalcemia
Ototoxicity
Nephritis

A

Loop Diuretics

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17
Q

a2 agonist

Hypertension, Cancer Pain, Opioid Withdrawal

A

Clonidine

18
Q

a2 agonist
Preeclampsia
Sedation, Positive Coombs

A

Methyldopa

19
Q

Ganglion Blocker
Hypertension - obsolete, Hypertensive Emergencies
Postural Hypertension

A

Hexamethonium

20
Q

Blocks VMAT
Hypertension - Obsolete
Depression, Suicidal Ideation

A

Reserpine

21
Q

Inhibit vesicular release of NE
Hypertension - Obsolete
Depression, Suicidal Ideation

A

Guanethidine

22
Q

Selective a1 blocker

BPH, HPN

A

Prazosin

23
Q

Blocks b1 and b2, Reduces Renin Release

Angina Prophylaxis, HPN, Glaucoma, Performance anxiety, Hypethyroidism

A

Propanolol

24
Q

Drugs used to control BP in Pheocrhromocytoma

A

Phenoxybenzamine
Phentolamine
Carvedilol
Labetalol

25
Q

Alters intracellular Ca
For preeclampsia
Drug induced Lupus

A

Hydralazine

26
Q

Opens K channels
Hypertension, Alopecia
Hypertrichosis, Hirsutism

A

Minoxidil

27
Q

Calcium channel Blocker - Non dihydropyridine

Hypertension, OPD DOC of Supraventricular Tachycardia

A

Verapamil

28
Q

SE of Verapamil

A

Gingival Hyperplasia

29
Q

Dihydropyridine CCB
Angina, Hypertension
Pretibial edema

A

Nifedipine

30
Q

SE of Pretibial edema

A

Nifedipine

31
Q

Relaxes both Venous and Arteriolar, inc NO -> Inc cGMP
Hypertensive Emergency
Cyanide Toxicity

A

Nitroprusside

32
Q

Vasodilation of Efferent and Afferent arterioles
Hypertensive Emergency
HYPOKALEMIA

A

Fenoldopam

33
Q

ACE inhibitor
HPN, Post MI
SE: COUGH

A

Capopril

34
Q

Blocks Angiotensin
For Hypertension
Hypoglycemia

A

Losartan

35
Q

Anti HPN, Contraindicated in Pregnancy

A

ACEi and ARBs

36
Q

Reduces aldosterone -> Hypokalemia

A

ARBs/ ACEis

37
Q

Inhibits Renin
Hypertension
Increase serum Crea

A

Alikskiren

Alis ka renin

38
Q

Antihypertensive, subarachnoid hemorrhage

A

Nimodipine

39
Q

Antidote for the Cyanide toxicity of Nitroprusside

A

Amyl nitrate

40
Q

Rising BP and rapidly progressing end organ damage

A

Malignant Hypertension

41
Q

Tx of Malignant HPN

A

Vasodilators + B Blockers + Diuretics

Virgil Ban Dijk