Cholinoreceptor Activating and Cholinesterase inhibiting Drugs

Question 1

Direct Acting Muscarinic
M and N receptors
Miotic during Ocular Surgery

Answer 1

Acetylcholinesterase

Question 2

Direct Acting Muscarinic
M receptors ONLY
BOWEL AND BLADDER ATONY

Answer 2

Bethanicol

Question 3

Direct Acting Muscarinic
M and N receptors
GLAUCOMA

Answer 3

Carbachol

Question 4

Direct Acting Muscarinic
M3 Receptors Only
Glaucoma, Sjogren, Sicca

Answer 4

Pilocarpine - Pirlo’s car in Seville is an M3

Question 5

Activates M3 receptors in ciliary muscle, inc aquaeous humor and salivary glands

Answer 5

Pilocarpine

Question 6

Activates Nn and Nm

For Smoking cessation

Answer 6

Nicotine

Question 7

Selective partial agonist at nicotinic receptors

Answer 7

Varenicline

Question 8

Fasciculation, Paralysis. Convulsion followed by CNS depression

Answer 8

Nicotinic Toxicity

Question 9

Indirect acting Cholinomimetics

Answer 9

Edrophonium
Neostigmine
Rivastigmine
Donepezil

I drop ni Neo si Riva kasi malilimutin siya that’s why hes done

Question 10

Tensilon Test - MG diagnostic

Answer 10

Edrophonium
Improves muscle strength - Myasthenic Crisis
Weakens - Cholinergic crisis

Question 11

Myasthenia gravis tx

Answer 11

Neostigmine

Question 12

Blocks Muscarinic effects of Neostigmine

Answer 12

Atropine

Question 13

Organophosphates -> AcHase inhibitor

Answer 13

Malathion

Parathion

Question 14

Indirect acting Cholinomimetics

For Alzheimer’s Disease

Answer 14

Rivastigmine

Question 15

Indirect acting Cholinomimetics

Combined with Memantine for Alzhemiers

Answer 15

Donepezil

Question 16

Organophosphate Poisoning

Answer 16

DUMBBELSS
Diarrhea
Urination
Miosis
Bronchospasm
Bradycardia
Excitation of CNS
Lacrimation
Salivation
Sweating

Question 17

Blocks ALL muscarinic receptors

First Choice Drug for Organophosphate poisoning

Answer 17

Atropine

Question 18

Side effect of atropine

Answer 18

Hyperthermia

Question 19

Cholinesterase regenerator

Antidote for Cholinesterase Inhibitor Poisoning (Early- within 6-8 hours)

Answer 19

Pralidoxime

Question 20

Prototype NONSELECTIVE muscarinic blocker

Answer 20

Atropine

Question 21

Plant where atropine is derived from

Answer 21

Atropa belladonna (Deadly Nightshade)

Question 22

Muscarinic antagonist

Used for Parkinson’s Disease

Answer 22

Benztropine
Biperiden
Trihexphenidyl

Sa Music Park Beep me to try our Bento

Question 23

Muscarinic Antagonist

For acute asthma and COPD

Answer 23

Ipratropium

Asthmatic cop is a prat

Question 24

Muscarinic Antagonist
For acute asthma and COPD
Does not cross BBB
May be used as Monotherapy in COPD

Answer 24

Glycopyrronium

Question 25

Muscarinic Antagonist | For motion sickness

Answer 25

Scopolamine Scoop me when im having motion sickness

Question 26

Blocks M3 | For Irritable Bowel Syndrome

Answer 26

Dicyclomine I ate 3 dice that made my bowel irritable

Question 27

Blocks M3 Reduces Detrusor muscle tone For urge incontinence

Answer 27

Oxybutinin Ox butt prevents me from urinating

Question 28

Atropine Toxicity

Answer 28

``` RED MAD HOT BLIND DRY ``` Red is Mad Hot but is Blind and Dry

Question 29

Contraindications of Muscarinic Blockers

Answer 29

Infants Acute angle closure glaucoma BPH Infants are cute angels with BPH

Question 30

Nicotinic Antagonist Completely blocks Nn and Ach receptors For Hypertension (Obsolete), Hypertensive emergencies

Answer 30

Hexamethonium

Question 31

Fastest neuromuscular blocker - Depolarizing

Answer 31

Succinylcholine Pag nagDEPOsit ka sa toilet Success yan