DIT weird bacteria Flashcards
What is leptospira interrogans?
question mark shaped bacteria b/c (INTERROGATEs)
Surfer in tropics (interrogate in point break).
Symptoms: early is flue like symptom and photophobia. THEN WEIL disease: WEILLY Bad. azotemia and liver/kidney dysfunction, fever, hemorrhage
What do you think if you see urine contaminated with urine?
Leptospira, hantavirus
Lyme disease mnemonic?
FAKE a key LYME pie
Facial nerve paralysis (bilateral)
Arthritis
Kardiac (AV) block
Erythema migrans
Tx for lyme disease? Stage 1 or stage 2 tx?
Late disease?
Doxy for early
Stage 3 (years later with subacute encephalitis and stuff is IV ceftriaxone)
Hand and foot rash mnemonic?
drive Kawasaki CARS with hands and feet.
Kawasaki
Coxcacki A
RMSF
Syphilis
Tertiary syphilis has what?
Gummas: chronic granulomas
Aortitis: tree bark aorta
Tabes dorsalis (sensory ataxia and positive rhomberg)
Argyll robertson (no light constriction but accommodation constriction is there)
Charcot’s joints: damage b/c slamming it into shit b/c pain doesn’t happen
Hutchinson teeth?
Weird looking teeth from congenital syphilis.
Treat early.
How do you recognize congenital syphilis in clinic?
Snuffles: bloody drips from nose.
Treat it and may prevent outcomes like saber shins, hutch teeth, mulberry molars, saddle nose…
What are VDRL/RPR?
Recognize serologic find antibodies in serum.
Can do false positive and confirm with FTA-ABS which is specific
Tx of primary syphilis?
Penicillin G, if allergic, use doxy
VDRL false positive?
VDRL
Virus
Drugs
Rheum fever
Lupus
Confirmwith FTA-ABS
Bartonella source?
cat scratch
Borrelia burgdorferi?
Ixodes tick (deer/mice)
Borrelia recurrentis
Tick and lice (relapsing fever)
Brucella?
undulant fever unpasturized milk
Campylobacter?
Pet contaminated fecal oral
Chlamydophila psittaci
Pneumonia parrots
Coxiella burnetii
Q fever: cattle placenta
Ehrlihia chaggeensis
Headache and blunt immune symptoms lone star tick
Francisella tularensis
Ticks and rabits (rabbit eating tulip on test
Leptospira interrigans
Animal urine
Pasteurella
cellulitis animal bites
Yersinia pestis?
prarie dogs and rats fleas
What disease might have bell’s palsy? Mnemonic
My Lovely Belle Had An STD
Lyme Herpes Zoster AIDS Sarcoid Tumor Diabetes
What is a ghon complex?
Hilar lymph and ghon focus on x ray. Primary Tb
Primary tb vs secondary in the lung?
Primary is ghon complex in mid lung
Secondary is cavitation with cavitary caseous necrosis in upper lobes and more symptoms
What bacteria often goes to back?
mycobacterium Tb in pott diseaes in extrapulmonary secondary Tb
Also can ht CNS, lymph, renal, GI, adrenal
Mechanism for drug for latent tb? What do you add to reduce toxicity?
INH is blocking synth of my colic acid and needs to be actriavatvie by catalase
pyridoxine helps with neuro and hepatotoxicity
Also causes lupus
Primary or secondary Tb tx?
RIPE
Rifampin
Isoniazid
Pyrazinamide (acidifies lysosomes of macrophage)
Ethambutol (less carb poly of mycobacterium cell wall and optic neuropathy)
Two kinds of leprosy? Tx for each?
Lepromatous is worse and communicable. Humoral response Th2
Tx: Dapsone, rifampin, clofazimine for 2-5 years
Tuberculoid: Tb some hairless skin plaques and cell0mediated immunity with Th1
Tx: dapsone and rifampin
Dapsone toxicity? When is it used?
Hemolysis in G6PD
PCP pnuemonia (in addition to TMP SMX) Lepromatous
When is rifampin used?
Tb
Leprosy
Meningitis prophylaxis: menigiococcal, H influenzae type B
Toxicity of RIPE regiment?
basically look out for hepatotoxicities
Gardnerella symptoms and tx?
Vaginosis: gray discharge and fishy smell Clue cells!
Metronidazole
Ricketsia triad and tx?
Headache fever and rash
Tx: Doxy
Where do ricketsial rashes start?
Ricketssia Rickets starts on wrRists and spreads in and includes soles
R typhi stratrts on Trunk and moves out sparing soles (also prowazeki)
Difference between endemic typhus and epidemic typhus?
Endemic is typhi from fleas
Epidemic is outbreaks from louse (lice) and prowazekii
Both start in central and spread but spare soles/palm
What is Q fever? what causes it?
Q fever is from Coxiella burnetii and similar to rickets
No rash or vector and is from cow placenta and has spores inhaled as aerosols and causes fever and pneumonia
Tx with doxy
What is weil felix reaction?
for rickets antibodies. Doesn’t work for Q fever (coxiella burnetii)
What is chlamydia psittaci?
Pnrumonia from birds that can spread systemically
Chlamydia trachomatis A, B and C?
Africa Blindness/Chronic infection
What is lymphogranuloma venereum? What can it be mistaken for?
Painless ulcers on genital that later are painful and ulcerate. Can cause rectal disease and mimic IBD.
Doxy is tx B/c chlamydia
What are cold agglutins? How do you treat causing bug?
IgM agglutinate or lyse RBC in cold environment
Seen with mycoplasma
Macrolide or doy or fluoroquinolone
What is coxiella burnetti?
Q fever cause. Cattle placenta and tick shit. Spores releasesd and inhaled
Pneumnia and Q fever is Queer: no rash or vector. No Weil-Felix (ricketsia test)
