DIT antiarrythmics Flashcards
What are the anti arrhythmic classes? Mnemonic
No Boy Keeps Clean
Na blockers I
Beta lockers II
K+ blocker III
Calcium channel is IV
Class Ia?
Class Ib?
Class Ic?
Na blockers (slow depolarization of myocytes)
Double Quarter Pounder
Disopyramide Quinidine, Procainamide
Lettuce Mayo Tomato
Lidocaine, Mexilitine, tocainade
Fries Please
Flecainaide, Prpafenone
What does 1a affect?
Slow depolarization, LONGER Effective refractory (longer QT)
What is used for WPW? What is symptom?
Procainamide (only time you use it)
SLE symptom (Procainamide in SHIPP mnemonic)
Side effects of quinidine?
Cinchonism (headache, dizziness, tinnitus), thrombocytopenia, torsades (longer QT)
Lidocaine use?
Acute ventricular tachyarrhythmia, digitalis, MOST MI
IB is Best post MI
What do you use post MI?
IB is Best post MI (B)
When is IC contraindicated?
isChemic disease IC is ContraindiCated.
Only used as a last resort in VT
How does a beta blocker help with arrhythmia?
Prolongs frequency of phase 4 in sinus.
Tx for overdose with beta blocker?
Glucagon (it activates things shut down by it, more cAMP)
What phase does class III work on?
Phase III. Slow down slow voltage gated potassium channel
Drugs of class III?
Sotolol and amiodarone, ibutilide, dofetilide (notice the first two are most common)
Amiodarone toxicity?
Check your:
PFTs: pulmonary fibrosis
LFTs: hepatotoxicity
TFTs: hyper or hypothyroidism (b/c a ton of IODINE in amIODaroNE)
Photodermatitis (SAT mnemonic with sulfonamides and tetracycline)
Neuro, constipation, VC…
corneal deposits
Pulmonary function test
liver function test
thyroid function test
Clacium channel blockers are what drugs?
Verapamil and ditiazem
What do IV drugs do?
Decrease conduction through AV b/c slows rise of action potential
Dihydropyridine vs non-dihydropyridine?
Dihydropyridine is for vessels and ends in dipine (DIhydroPiridINE)
Nondihydropyridine is in heart and has non of those letters
Symptos of IV?
well they may have unintentional effects in periphery: flushing and edema.
Also constipation, CHF of course with the effect of drug, AV block, yeah sinus node depression, yeah
Adenosine mechanism?
Increases K+ leaving cell, so hyper polarizes the cell, so everything restarts as it drops down. But then metabolized fast, and it works again
Adensoine use?
SVT Dx and Tx
What is adenosine blocked by?
Theophylline (asthmatic or COPD patients)
Magnesium use?
torsades
