Digestion 1 Flashcards
What is the sole purpose of the digestive system?
Extract useful nutrients from ingested food and fluids
The digestive system is simply a “long tube” going through the body. What is the name given to this “tube”?
Alimentary canal
The ‘alimentary canal’ consists of 6 parts. What are they?
- Oral cavity
- Pharynx
- Esophagus
- Stomach
- Small intestine
- Large intestine
The digestive system has organs which are not part of the alimentary canal, but aid in digestion. What is the general name of all of these organs?
Accessory organs
There are 6 accessory organs that aid in digestion. What are they?
- Pancreas
- Gallbladder
- Liver
- Salivary glands
- Teeth
- Tongue
What is ‘enteritis’, and what is it commonly called and caused by?
Inflammation of the intestinal mucosal lining.
Commonly called intestinal flu.
Caused by viruses, bacteria, or certain foods.
What is the common meaning for ‘deglutition’?
Swallowing
What are some of the characteristics of the ‘oral cavity’? (There are 6 of them)
- Ingest food
- Receive saliva
- Mastication
- Digestion of carbohydrates
- Formation of ‘bolus’ (food mass)
- Deglutition (swallowing)
What are some of the characteristics of the ‘pharynx’? (There are 3 of them)
- Receive bolus from oral cavity
- Autonomically continues deglutition of bolus
- Passes to ‘esophagus’
What are some of the characteristics of the ‘esophagus’? (There are 2 of them)
- Moves bolus to stomach via peristalsis (muscle moving waves)
- Esophageal sphincter restricts back-flow of food
Which sphincter restricts the back-flow of food from the esophagus to the pharynx?
Esophageal sphincter
What is ‘peristalsis’?
The movement of a bolus via the muscles in the esophagus/intestines.
What are some of the characteristics of the ‘stomach’? (There are 7 of them)
- Receives bolus from esophagus
- Churns bolus w/ gastric juice and forms chyme
- Digestion of proteins
- Limited absorption
- Chyme moves to duodenum
- Back-flow of chyme prohibited
- Can vomit
What is ‘chyme’?
Chemical breakdown of a bolus when mixed with gastric juices
What are some of the characteristics of the ‘small intestine’? (There are 5 of them)
- Receives chyme from stomach
- Chemically/Mechanically breaks down chyme
- Absorbs nutrients
- Transports wastes via peristalsis to large intestine
- Prohibits back-flow of intestinal wastes from large intestine
What are some of the characteristics of the ‘large intestine’? (There are 4 of them)
- Receives undigested waste from small intestine
- Absorbs water and electrolytes
- Forms and stores feces
- Expels waste via defecation reflex
Where does digestion start and how?
Starts in the mouth with saliva and is broken down into smaller particles
Mastication (chewing) is important because it does what to the food? Why is this important?
Increases the surface area of the food
Rate of digestion depends on the total surface area exposed
There are 3 processed involved with digestion that start in the mouth. What are they?
- Mastication (chewing)
- Food is lubricated w/saliva
- Digestion starts w/amylase
What does ‘amylase’ do?
ONLY breaks down starch/carbohydrates
What do the salivary glands secrete, and where do they secrete?
- Saliva
2. Buccal cavity
Saliva contains a substance that acts as an antibiotic. What is it?
Lysozyme
Saliva secretion is stimulated by 3 things. What are they?
- Taste
- Smell
- Tactile stimuli w/tongue
What is the daily amount of saliva secretion?
800-1500 ml
What is the pH of saliva?
7-Jun
What is the percentage of H2O and solutes in saliva?
H2O = 99.5% Solutes = 0.5%
True of False:
The salivary glands are under sympathetic control.
FALSE
Salivary glands are under PARASYMPATHETIC control
(Rest/Digest)
There are 3 paired glands involved in saliva secretion. What are the 3 paired glands?
- Large parotid
- Submandibular gland
- Sublingual gland
Which two salivary glands secrete both serous and mucous enzymes?
- Submandibular gland
2. Sublingual gland
What salivary gland secretes only serous fluid-enzymes?
Large Parotid
What are the characteristics of ‘mumps’?
Viral disease of the parotid salivary gland
What are the characteristics of ‘parotitis’ disease?
Inflammation of parotid gland
What are the characteristics of ‘ptyalocele’ disease?
Cystic tumor of a salivary gland
How many taste buds do humans have? How many taste cells are there per bud?
4000 Taste buds
30-100 Taste cells/bud
What type of receptors are involved in taste?
Chemoreceptors
The esophagus is a ‘thin’ muscular tube that moves food from the ________ to the _______.
Pharynx to the Stomach
How long is the ‘esophagus’?
10-12 inches long
Where is the ‘esophagus’ located behind?
the trachea
The lower end of the esophagus has a sphincter that is called by two names. What are they?
- Cardiac sphincter
2. Gastroesophageal sphincter
The esophageal sphincters prevent what from entering into the esophagus?
Stomach acid
What are some of the characteristics of ‘heartburn’?
Regurgitation of gastric contents into esophagus
Epithelial layer is ‘burned’ away
(G.E.R.D) - Gastro Esophagial Reflux Disorder
What is the definition of ‘achalasia’?
Lower esophageal sphincter (cardiac sphincter) fails to relax.
Someone with ‘achalasia’ will have which of the following symptoms? (There are 4 of them)
- Dysphagia (difficulty swallowing)
- Substernal pain (mimics angina)
- Food may remain in esophagus for hours
- Possible regurgitation into pharynx
What are the characteristics of ‘angina’?
Painful constriction or tightness somewhere in the body
What are some of the causes of ‘achalasia’? (There are 3 of them)
- Abnormal parasympathetic stimulation
- Drinking cold liquids
- Excess gastrin secretion
What are some of the management solutions for possible ‘achalasia’?
Ruling out possible heart problems
Surgery or use of special dilating balloon to expand esophagus
What is the scientific name for an esophageal tumor and what are the characteristics of them?
Carcinoma
Obstruction of the esophagus
Accounts for about 2% of all cancer deaths in the U.S.
What does ‘nitroglycerin’ do?
Causes smooth muscle to relax
‘Nitroglycerin’ can help two specific disorders. What conditions are they?
- Angina (Problem w/heart)
2. Achalasia (Failure for muscle to relax)
Having a Hiatal Hernia has four common characteristics. What are they?
- Dysphagia (difficult swallowing)
- Heartburn
- Epigastic pain
- Gastroesophageal reflux
How long does it take the stomach to empty into the small intestines after eating a meal?
2-4 Hours
Why does very little absorption take places in the stomach?
Because tight junctions between epithelial cells line the stomach.
Which 3 substances are very common in the absorption in the stomach?
- Aspirin
- Alcohol
- Water
What functions do the ‘parietal cells’ in the stomach have?
- Secrete HCl
2. Secrete intrinsic factor
HCl that is secreted from parietal cells have what function in the stomach?
Kills bacteria in food
Converts pepsinogen to pepsin
‘Intrinsic factor’ that is secreted from parietal cells in the stomach have what function?
Allows ileum of small intestine to absorb ‘VITAMIN B12’.
‘VITAMIN B12’ is required for ‘erythropoiesis’
What functions do the ‘mucus cells’ in the stomach have?
Secrete mucus
Protects the stomach lining
What functions do the ‘zymogenic cells’ (chief cells) in the stomach have?
Secrete pepsinogen
In acidic conditions. Pepsinogen becomes pepsin.
What does the ‘pepsin’ enzyme do?
Digests proteins
Zymogenic cells are also called what kind of cells?
Chief cells
What are some of the characteristics of ‘pyloric stenosis’?
Narrowing of pyloric sphincter
Projectile vomiting = 3-4 feet
Males = 5/1000
Females = 1/1000
Caused by enlargement of circular muscle fibers
What is the main treatment for ‘pyloric stenosis’?
A ‘pyloromyotomy’.
Muscle cells are split and separated.
What are all ulcers usually generally called?
Peptic ulcers
Peptic ulcers are usually caused when the stomach, esophagus or duodenum is attacked and digested by what TWO enzymes?
- HCl
2. Pepsin
Where does a gastric ulcer occur?
Stomach
Where does a duodenal ulcer occur?
First part of the small intestine (Duodenum)
Where does a esophageal ulcer?
Lower part of the esophagus
There are 7 causes for peptic ulcers. What are some of them?
- Stress
- Poor eating habits
- Excess vagal stimulation
- Hypersecretion of HCl/Pepsin
- Hypersecretion of adrenal coriticoids
- Lack of mucus
- Presence of irritating chemicals (steroids, anti-inflammatory agents, caffeine, alcohol, tobacco, or aspirin)
Approximately what percentage of the population has peptic ulcers?
10%
How are peptic ulcers usually treated?
Diet/drugs
Sometimes surgery
What drug helps ulcers by blocking H2 receptors in the stomach thus decreasing secretion of HCl?
Tagamet (#1 drug for over 10 yeras)
__% of all peptic ulcers are caused by ___________ ______?
- 80%
2. Helicobacter pylori
In order to kill H. Pylori, what treatment is usually necessary?
3 different antibiotics taken 3 times a day
__% patients who are infected with H. Pylori will develop an ulcer in their lifetime.
20%
How does vomiting occur?
The relaxation of the cardiac sphincter
Strong contraction of the diaphragm and abdominal muscles
Vomiting may be caused by 6 different things, what are some of them?
- Toxic food
- Gagging
- Excessive distension of the stomach
- Intense pain
- Dizziness
- Sight or smell of things unpleasant to the person
Vomiting is considered to be a _______ mechanism that does what?
- Defense mechanism
2. Get rid of hazardous waste
What is the ‘small’ intestine called small?
Because of the ‘diameter’
How long is the small intestine?
20 feet
What are the characteristics of intestinal juice? (Color/Amount/pH)
- Color = CLEAR
- Amount = 1000-2000 ml/day
- pH = 7.6
What percetage of digestion and absorption occur in the small intestine?
90%
What are the glands that secrete mucs to protect the small intestine from gastric juice?
Brunner’s Glands
The small intestine is separated into three different division, what are the three divisions and how long is each one?
- Duodenum (10-12 inches)
- Jejunum (8 feet)
- Ileum (12 feet)
Which division of the small intestine dumps into the large intestine?
Ileum
The small intestine produces 3 enzymes to help digest the three major food materials.
What are the 3 enzymes and what food material do they digest?
- Peptidase - PROTEINS
- Carbohydrase - CARBOHYDRATES
- Lipase - FATS or LIPIDS
Small intestine receives external secretions from 2 other accessory organs. What are the 2 accessory organs?
- Pancreas
2. Gall bladder
What is the large intestine also known as?
Colon
The large intestine is divided structurally into 3 parts. What are the 3 parts?
- Cecum
- Colon
- Anal canal
What is the function of the ileocecal valve in the large intestine?
Prevent backflow to the ileum (small intestine)
The colon (large intestine) is separated into 4 sections. What are the 4 sections?
- Ascending colon
- Transverse colon
- Descending colon
- Sigmoid colon
Where is the appendix located and what is it attached to?
Located in the large intestine
Attached to the cecum
What are the 3 functions of the large intestine?
- Absorption of water/electrolytes
- Storage
- Expulsion of feces from digestive
What is diarrhea?
Intestinal wall becomes irritated and peristalsis increases
Lack of absorption of water
helps body rid of infectious organisms.
What are the 2 major causes of diarrhea?
- Infection of lower GI tract
2. Nervous stimulation
True or False:
Laxatives should be used whenever needed. The body can not become dependent on laxatives.
FALSE
Laxatives should ONLY be used when necessary because the body CAN become dependent on laxatives.
Constipation usually results from a diet that lacks what 2 things?
- Water
2. Roughage
This helps provide increased regularity and MAY also help protect the body from colon cancer.
Fiber
There are 4 major types of laxatives. What are the 4 major types and what are some examples of the types?
- Bulk Laxatives - Bran/Fiber
- Lubricants - Mineral Oil
- Mineral Salts - Magnesium. (Are not absorbed, increase osmotic pressure of fecal material)
- Irritants - Speed up peristalsis
The appendix does not function in humans is prone to infection. In other animals what is it’s function?
Home for bacteria that digest cellulose
What are some of the symptoms of appendicitis?
- Severe pain in the right abdominal region
2. Tenderness/Swelling
If appendicitis is left untreated, what might occur?
Appendix may burst and cause infection to spread (Gut to Ab cavity)
What is ‘peritonitis’?
When the appendix bursts and causes infection to spread from gut to lining of ab cavity
Irritable bowel syndrome is also often called __________.
Spastic colitis
What are the characteristics and causes of ‘Irritable Bowel Syndrome (IBS)’?
- Abdominal discomfort
- Irregular bowel function
- Loud gurgling sounds
Caused by emotional stress
What is a colostomy?
Surgical procedure in which an abdominal exit is made for the colon. *(Colon bypass or ‘bag’)
What is dysentery?
Inflammation of intestinal mucosa with bleeding and mucus discharge with the stools.
Lipase breaks down fasts into what?
Glycerol and 3 fatty acids