Diabetes Flashcards
Can corticosteroids precipitate hyperglycaemia?
YES
Where is insulin made?
Islet cells in pancreas
What is Diabetes Mellitus?
Metabolic diseased characterised by hyperglycaemia from defects in insulin production/function.
What is the prime reason for Type 1 ?
Pancreatic cell destruction
What is the prime reasons for Type 2?
Beta cell dysfunction
Insulin resistant
What is insulin resistant?
The receptor is not as responsive to the insulin molecule so less glucose enters the cell- build up in blood
As Beta cell function declines, what increased?
Blood sugar levels
What is the treatment for Type 2? (4 steps)
Diet and exercise
Oral monotherapy
Oral combination
Injection and oral therapy
What is Biguanide?
Metformin for Type 2
What is Sulfonylurea?
The second option for Type 2 (or if metformin is not suitable)
What is TZD?
3rd option for Type 2 drugs
What is HbAIC?
Average blood glucose over 6-8 weeks
What should HbAIC be at?
4.6% however 6.5-7.5 for diabetics
What is HBGM?
Home blood glucose monitoring
What should HBGM be?
4-7, but under 10 after meals