Dextrose

Question 1

D50

Class

Answer 1

• Carbohydrate
• Hypertonic solution

Question 2

D50

Mechanism of action

Answer 2

• Rapidly increases serum glucose levels
• Short term osmotic diuresis

Question 3

D50

Indication

Answer 3

• Hypoglycemia
• Altered LOC
• Coma of unknown etiology
• SZ of unknown etiology
• Status epilepticus

Question 4

D50

Contraindications

Answer 4

• Intracranial hemorrhage (relative contra)

Question 5

D50

Adverse Reactions

Answer 5

• Extravasation causes tissue necrosis
• Warmth, pain, burning, thrombophlebitis
• Rhabdomyolysis
• Hyperglycemia

Question 6

D50

Drug interactions

Answer 6

• Coumadin
• Sodium Bicarbonate

Question 7

D50

Dosage and administration

Answer 7

• Adult:
  
  • 12.5-25 gram, slow IV
• Ped:
  
  • 0.5-1.0 g/kg slow IV
• Repeat as needed

Question 8

D50

Duration of action

Answer 8

• Onset: Less than 1 min
• Peak: Varies
• Duration: Varies

Question 9

D50

Special considerations

Answer 9

• Administer thiamine prior to D50 in known alcoholics
• Draw blood for lab BGL prior to pushing D50
• Do not give to PT with CVA unless hypoglycemia is documented