Development of Vasculature Flashcards

1
Q

Blood vessels develop from

A

Angioblastic cords from mesoderm

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2
Q

Livers role

A

Main hematopoietic organ until others take over

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3
Q

Where do small blood vessels first form and what do they become?

A

In extraembryonic mesoderm of connecting stalk

Umbilical cord

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4
Q

When folding is occurring, where are blood vessels developing and are they connected?

A

IN yolk sac, vitelline duct, and connecting stalk

No

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5
Q

Prominant artery during folding

A

Dorsal aortae

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6
Q

Each pharyngeal arch will have ______ and what are they derived from?

A

a pair of aortic arches

From aortic sac of heart

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7
Q

Aortic arches connect distally to

A

Pair of dorsal aortae

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8
Q

Dorsal aortae connect to yolk sac by _____ and placenta by _____

A

Vitelline art

Umbilical art

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9
Q

Three vitelline arteries survive to become______

A

Unpaired arteries of adult that supply foregut, midgut, and hindgut

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10
Q

Remnants of umbilical arteries

A

Ligamentous remnants from internal iliac artery

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11
Q

Lateral folding and dorsal aortae

A

Causes the two dorsal aorta to form a single aorta caudal to the neck
In neck and head, they remain separate

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12
Q

Distally, two dorsal aorta fuse to form

A

Common aorta

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13
Q

Aortic sac

A

Rostral common outflow of developing heart and connects heart to pairs of aortic arches

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14
Q

Truncus arterioies

A

Common tube leading from heart to aortic sac

Forms asecnding aorta and pulmonary trunk

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15
Q

1st aortic arch…what does it form and when does it form

A

First and disappears first

Forms maxillary artery that supplies deep regions of face

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16
Q

2nd aortic arch…what does it and form and when

A

Begins to lose connection with aortic sac after formed but still connected to dorsal aorta
Forms stapedial artery which regresses

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17
Q

Dorsal aorta between which two arches is lost?

A

3rd and 4th

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18
Q

Postion of dorsal arota cranial to 3rd aortic arch forms

A

Continuous tube with 3rd arch

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19
Q

External carotid from

A

proximal part of 3rd aortic arch

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20
Q

Common arotid from

A

Part of 3rd aortic arch proximal to external arotids origin

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21
Q

Aortic sac regresss where?

A

In region where 3rd aortic arch arises

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22
Q

What is notable segmental artery?

A

7th cervical intersegmental artery sprouts from each dorsal aorta proximal to their fusion

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23
Q

Where do segmental arteries arise forom

A

Dorsal aorta

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24
Q

4th aortic arches fate

A

Remain associated with aortic sac

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25
Q

6th aoritc arches fate

A

Remain associated with aortic sac and trunucs arteroisis

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26
Q

Truncus arteriosis and aortic sac undergo septation to form

A

Pulmonary trunk and ascending aorta

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27
Q

aortic sac associated with which arch is lost?

A

6th

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28
Q

6th aortic arch becomes continuous with

A

Truncus arteriosis

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29
Q

What sprouts from 6th aortic arch?

A

Right and left pulmonary arteries

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30
Q

Which portion of 6th aortic arch is lost?

A

Right part distal to the sprouting artery

31
Q

What part of 7th intersegmental is lost

A

Right dorsal aorta

32
Q

Continuous vessel form between which after 7th segmental artery loses right dorsal aorta

A

Right dorsal aorta, right 7th intersegmental, right 4th aortic arch

33
Q

Right 4th aortic arch becomes

A

Right subclavian

34
Q

3rd aortic arches become

A

Common carotid, proximal part of internal carotid, external carotid

35
Q

Left 4th aortic arch becomes

A

Aortic arch between left common carotid and left subclavian artery

36
Q

Right 4th aortic arch becomes

A

Proximal part of subclavian artery

37
Q

Prixmal right and left 6th aortic arches become

A

Proximal parts of right and left pulmonary arteries

38
Q

Distal left 6th aortic arch forms

A

Ductus arteriosis

39
Q

Aortic sac associated with and forms

A

4th arch

Ascending aorta, part of arch of aorta, right brachiocephalic artery

40
Q

Right dorsal aorta forms

A

Intermediate portion of right subclavian artery

41
Q

7th intersegmental arteries form

A

Parts of right subclavian and all of left subclavian

42
Q

Left dorsal aorta forms

A

Descending aorta

43
Q

Double aortic arch

A

Right dorsal aorta persists between 7th intersegmental artery and junction with left dorsal aorta
Can compress trachea and esophagus

44
Q

Coarctation of aorta

A

Constriction of aorta mostly at ductus arteriosis

45
Q

Postductal coarctation

A

Constriction just distal to ductus arteriosis

Permits development of collateral circulation during fetal development that helps supply blood to inferior parts of body

46
Q

Preductal coarctation

A

If severe, can be given prostaglandin E2 to try to reopen ductus arteriosis

47
Q

Liver invades _____ and causes them to form _____

A

Both vitelline veins

Hepatic sinusoids

48
Q

Parts of hepatic sinusoids coalesce to form

A

Ductus venosus

49
Q

What anastomoses with ductus venosus

A

Left umbilical vein

50
Q

Right vitelline vein distal to liver becomes

A

Hepatic portal vein

Superior mesenteric vein

51
Q

Hwat becomes umbilical vein?

A

Distal portion of left umbilical vein

52
Q

Ductus venosus allows

A

Blood to enter directly enter heart

53
Q

Left umbilical vein atrophies to becomes

A

Ligamentum teres hepatis

54
Q

Ductus venosus atrophies to becomes

A

Ligamentum venosum

55
Q

Anterior and posterior cardinal veins drain

A

Blood from head and neck

Remainder of embryo

56
Q

Common cardinal drains to

A

Sinus venosus

57
Q

Distal right anterior cardinal vein becomes

A

Brachipcephalic vein (right)

58
Q

Anastomosis between right and left anterior cardinal veins and remainder of rostral left cardinal vein becomes

A

left brachiocephalic vein

59
Q

Proximal right anterior cardianl vein and right common cardinal vein becomes

A

Superior vena cava

60
Q

Supracardinal veins develop from what and receive drainage from

A

Posterior cardinal veins - eventually anastomose

Somite segmental veins

61
Q

Which supracardinal vein loses connection and where odes it drain

A

Left proximal

Drains to left proximal posterior cardinal vein

62
Q

Right supracardinal vein becomes

A

Azygos vein

63
Q

Left proximal supracardinal vein becomes

A

Accessaory hemiazygos vein

64
Q

Left distal supracardinal vein becmes

A

Hemiazygos veins

65
Q

Supracardinal veins become

A

azygos system

66
Q

Segmental vessels become

A

intercostal veins

67
Q

Which part of cardinal veins persist and what do they become?

A

Caudal posterior cardinal veins

Become part of interior vena cava and common iliac

68
Q

Subcardinal veins form

A

Part of IVC

69
Q

Right subcardinal vein connects to

A

Supracardinal vein

70
Q

Right subcardinal vein loses connection to

A

Right posterior cardinal vein

71
Q

IVC formation

A

Right vitelline - hepatic
Right subcardinal - suprarenal
Supracardinal - infrarenal
POsteroir cardinal - caudal and common iliac veins

72
Q

Loss of right sixth aortic arch allows

A

Right recurrent loop of vagus to loop around right fourth aortic arch

73
Q

Left sixth aortic arch is

A

Maintain and left recurrent says in same position

74
Q

Which recurrent branch of vagus nerve is higher?

A

Right