Dermatology+ENT+Opthal (passmed) Flashcards
Pellagra?
Presents with 4 D’s:
-Diarrhoea
-Dermatitis
-Dementia
-Death
NB: Isoniazid(TB medication) is known to induce Pellagra.
Is caused by Nicotinic acid (Vitamin B3, Deficiency(niacin)
Erythema Nodosum presentation:
- Painful red bruises on shins and forearm; is an inflammation of the subcutaneous fat.
- Can also be associated with systemic diseases like: Sarcoidosis, Inflammatory Bowel Disease, Streptococcal Infection
- usually resolves within 6 weeks
ddx: ITP (however bruises are NOT painful in this)
Burns: for what type of burn is IV fluids required?
- Only give IV fluids for second/third degree burns that cover 15% of body surface or more for eg. For second degree(superficial DERMAL, partial thickness and more severe), NB: IV fluids are not required for first degree burns.
SLE skin manifestations:
-photosensitive butterfly rash
-discoid lupus
-alopecia
-livedo reticularis (net-like rash)
Sebborhoeic dermatitis complications:
- Otitis Externa (causes inflammation- redness and swelling to external ear canal; is also referred as swimmer’s ear)
-Blepharitis (inflammation along edge of eyelids) - Associated conditions include: HIV, Parkinson’s Disease
-1st line mx: Topical Ketoconazole
Erythema Multiforme:
- Giant NON-ITCHY target lesions on forearm
= The name of target lesions comes from the fact they have three concentric colour zones, a darker centre with a blister, a ring around this that is paler pink and raised due to oedema and a bright red outermost ring.
Most common medication causes:
- Aminopenicillins (such as co-amoxiclav), sulfonamides, carbamazepine, allopurinol, NSAIDs and oral contraceptive pill.
Psoriasis exacerbating factors:
- beta blockers for eg. Atenolol, lithium, NSAIDs, ACE-i
- trauma
-alcohol
Pathogen to trigger Guttate psoriasis:
Streptococcal infection
Rosacea acne triggers:
- Alcohol
- spicy food
- Hot drinks
Presents with: on nose, cheek, forehead with flushing, erythema, telangiectasia(papules and pustules)
- sunlight can worsen symptoms, if ocular involvement= Blepharitis( swollen, itchy eyelids)
Mx: 1st line- Topical Ivermectin +/- oral doxycycline. alternatives: Topical metronidazole/azelaic acid
-Simple: high factor sunscreen
- Topical Brimonidine gel
- can consider laser therapy if patient has prominent telangiectasia
Lichen Sclerosus:
Presents with: white patches affecting genitalia that may scar+ itch
Mx: topical emollients and steroids
- happens in elderly females
- clinical diagnosis can be made
Erythema ag igne:
happens due to application of hot water bottle on an area for a period of time.
- presents with an area of erythema
Acanthosis Nigricans:
- Skin with: dark, thickened patches of skin that appears on axilla
- Velvety, hyperpigmented rash
- is an early sign of Type 2 Diabetes
Ddx: Hidradenitis suppurativa: but this has painful lumps and more prone to recurrent abscesses under the skin.
Allergic Rhinitis:
Presents: Symptoms come on same time each year
- Bilateral nasal obstruction, cough at night, clear nasal discharge, post-nasal drip, sneezing, nasal pruritus
Mx: avoid allergen triggers
- oral/intranasal antihistamines
-severe: intranasal corticosteroids
Erythema Nodosum:
Presents:
- Painful red bumps under skin of SHIN
- can occur in pregnancy due to hormonal changes AND infection with strep.= common cause.
Sudden loss of vision + diabetes
Vitreous Haemorrhage: presents with= red hue to the vision
Also presents with:
- dark spots obscuring vision/complete of vision if bleed is big enough
Ddx: Retinal detachment
Central retinal artery occlusion:
- Sudden unilateral loss of vision in absence of pain
- O/E: RAPD (relative afferent pupillary defect) + fundoscopy: pale retina with cherry-red dot at macula.
Optic Neuritis other disease association: (Neuro)
-Multiple Sclerosis
Optic Neuritis:
- Pain on movement of the eye and often pain behind eye, funny colour, RAPD, reduced colour vision (red desaturation)
- Mx: high dose steroids, recovery usually takes 4-6 weeks
-Inv: MRI of brain; is usually diagnostic
Anterior Uveitis association disease:
- Ankylosing Spondylitis
Difference between: Anterior Uveitis vs. Acute angle closure glaucoma=
Glaucoma= severe pain, haloes, ‘semi-dilated’ pupil
Uveitis= small, fixed oval pupil, ciliary flush/congestion, often presents with nausea and vomiting, blurred vision+ sudden onset severe ocular pain.
Anterior Uveitis (same are Iritis):
- Presents with: unilateral eye pain, photophobia (often intense) , ciliary congestion
- Mx: Treated with steroid+ cycloplegic (mydriatic) drops
- Crohn’s Disease is associated with the condition
- Also needs URGENT review by ophthalmology
Episcleritis vs. Scleritis:
Episcleritis: PAINLESS red eye, injected vessels=mobile when gentle pressure is applied on sclera
-classically painless
-Mx: conservative, artificial tears may be used.
Scleritis: vessels are deeper and hence do not move