dermatology Flashcards
how can topical tx be given?
shampoo
cream
ear drops
name the seborrheic agents
sulphur
salicyclic acid
tar
selenium suphide
why is sulphur useful ?
stops keratocyte prolif and softens them
antimicrobial and antifungal
use with salicyclic acid as this is hydrating
what do anti-sebhorreic agents do
keratoplastic keratolytic anti-pruritic degreasing vasocon
what is keratoplastic
cytostatic on basal stem keratocytes
what is keratolytic
damage the str corneum, stim shedding
what animal is tar toxic to
cats
what is tar very good at (crap at other things..)
degreasing - so will dry out skin!
why is selenium sulphide rarely used
owners dont like it - stains coat
name some main anti-microbial agents
benzoyl peroxide chlorhexadine ethyl lactate iodine triclosan miconazole
what is chlorhexadine most active against
staph
NOT fungi
why is chlorhexadine so popular
residual activity
not irritant
non toxic
iodine is a fab bacterio-, fungi-, viru- and sporo- CIDE. why wont owners like it
stains coat
what is triclosan and why is it used
anti-microbial
effective againt MRSA (supposedly)
what is miconazole
azole, antifungal. used with chlorhexadine to tx malassezia pachyd
what are emolients?
help move other ingredients aX skin (forms thin oil). good to maintain hydration
what is a moisturiser?
surface of skin covered
name some moisterisers
urea
glycerin
propylene glycol
FAs
name some anti-pruritic agents
hydrocortisone
anti-hist
aloe vera (inhib COX)
how do you tx immune-mediated skin disease
tacrolimus (macrolide, like cyclosporin)
what is otitis externa?
inflam of ext ear, inside pinna. b
what must you do before topical ear drop tx -
ensure tympanic membrane is intact
what are the common ingredients in canural (other ear drops)
g-corticoids to dec inflam and widen canal
anti-bacterials - C&S
anti-fungals - malassezia pachyderma
anti-para - otedectes cynotis
