dermatology Flashcards

1
Q

how can topical tx be given?

A

shampoo
cream
ear drops

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2
Q

name the seborrheic agents

A

sulphur
salicyclic acid
tar
selenium suphide

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3
Q

why is sulphur useful ?

A

stops keratocyte prolif and softens them
antimicrobial and antifungal
use with salicyclic acid as this is hydrating

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4
Q

what do anti-sebhorreic agents do

A
keratoplastic
keratolytic
anti-pruritic
degreasing
vasocon
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5
Q

what is keratoplastic

A

cytostatic on basal stem keratocytes

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6
Q

what is keratolytic

A

damage the str corneum, stim shedding

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7
Q

what animal is tar toxic to

A

cats

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8
Q

what is tar very good at (crap at other things..)

A

degreasing - so will dry out skin!

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9
Q

why is selenium sulphide rarely used

A

owners dont like it - stains coat

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10
Q

name some main anti-microbial agents

A
benzoyl peroxide
chlorhexadine
ethyl lactate
iodine
triclosan
miconazole
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11
Q

what is chlorhexadine most active against

A

staph

NOT fungi

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12
Q

why is chlorhexadine so popular

A

residual activity
not irritant
non toxic

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13
Q

iodine is a fab bacterio-, fungi-, viru- and sporo- CIDE. why wont owners like it

A

stains coat

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14
Q

what is triclosan and why is it used

A

anti-microbial

effective againt MRSA (supposedly)

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15
Q

what is miconazole

A

azole, antifungal. used with chlorhexadine to tx malassezia pachyd

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16
Q

what are emolients?

A

help move other ingredients aX skin (forms thin oil). good to maintain hydration

17
Q

what is a moisturiser?

A

surface of skin covered

18
Q

name some moisterisers

A

urea
glycerin
propylene glycol
FAs

19
Q

name some anti-pruritic agents

A

hydrocortisone
anti-hist
aloe vera (inhib COX)

20
Q

how do you tx immune-mediated skin disease

A

tacrolimus (macrolide, like cyclosporin)

21
Q

what is otitis externa?

A

inflam of ext ear, inside pinna. b

22
Q

what must you do before topical ear drop tx -

A

ensure tympanic membrane is intact

23
Q

what are the common ingredients in canural (other ear drops)

A

g-corticoids to dec inflam and widen canal
anti-bacterials - C&S
anti-fungals - malassezia pachyderma
anti-para - otedectes cynotis