Day 2 Flashcards
what eye finding is associated with MS?
internuclear opthalmoplegia
what is internuclear opthalmoplgeia?
conugate horizontal gaze
what is issue in internuclear opthalmoplegia?
medial longitudinal fasciculus
what are features of PNH?
dark urine, hemolysis, hepatic vein thrombosis, fatigue
what is rx of PNH?
eculizumab
pregnant patient has significant hemorrhage, what position should they be in?
left lateral decubitus
what are drug options for mild to moderate dementia?
rivastigmine, donepezil and galantamine
what is drug option for severe dementia?
memantine
women with migraines with aura should stop what medication? why?
OCP, at increased risk of stroke
what is cause of infertility in klinefelter?
semineferous tubule dysgenesis
what is karyotype of klinefelter?
47XXy
what are findings in klinefelter?
tall stature, small balls, infertility, gynecomastia
what is fetal hydantoin syndrome?
in utero exposure to phenytoin, valproate or carbamazapine
what are findings of fetal hydantoin syndrome?
cleft lip/palate, wide anterior fontanelle, cardiac isses, distal phalange hypoplasia
what are classic findings of interstitial nephritis?
rash, fever, eosinophilia, WBCs in urine
vertigo can be presenting symptom of what type of stroke?
posterior circulation (vertebral artery)
hyper IgE syndrome is associated with what blood finding?
eosinophilia
hyper IgE leads to what type of infections?
lots of eczema and reccurent abscesses and sinopulmonary infections
what is unique about development in hyper IgE syndrome?
retained primary teeth
what is treatment of hyper IgE syndrome?
supportive skin care
what are some topical treatment options for acute angle closure glaucoma?
timolol, pilocarpine and apraclonidine
what are risk factors for vaginal hematoma?
forceps delivery, big baby, prolonged 2nd stage of labor
what is clinical sign of vaginal hematoma?
patient getting shocky and has a vaginal mass
what is treatment of vaginal hematoma?
if not expanding, observe. if expanding surgery
what is formula for Number needed to harm?
1/absolute risk increase….to calculate absolute risk increase it is rate of AE with intervention minus rate of AE without intervention
two options for endometrial hyperplasia management?
give progestins or hysterectomy
what are lab findings in MM?
normocytic anemia,
renal insufficiency,
hypercalcemia
M spike
what is radiology finding in MM?
osteolytic lesions of bones
what are some common signs/sx of MM?
bone pain, constipation, weight loss, fatigue and recurrent infections
what Ig is elevated in MM?
IgG or IgA
IgM spike is daignostic of what?
waldentstroms macroglobulinemai
what age should baby begin to respond to name?
6 months
what are emergency contraception options?
single pill of ulirpristal, oral levanorgestrol, IUDs
in secondary adrenal insufficiency, what are levels of ACTH, cortisol and aldosterone?
ACTH and cortisol low, aldosterone normal
in primary adrenal insufficiency, what are levels of ACTH, cortisol and aldosterone?
cortisol and aldosterone are low and ACTH is high
which of primary or secondary adrenal insufficiency has skin changes?
primary gets skin hyperpigmentation
what are three main findings in cauda equina syndrome?
saddle anesthesia, severe unilateral radicular pain, bowel/bladder issues
what is rx of cauda equina syndrome?
surgical decompression
what heme findings can occur in HELLP syndrome?
MAHA and thrombocytopenia
what can happen to lungs in HELLP/preeclampsia?
pulmonary edema
what med should sickle cell pregnant patients be taking?
aspirin
what are obstetric complications that patients with sickle cell are at increased risk for?
abruption, preeclampsia, spontaneous abortion
what acid base disturbance is normal in pregnancy?
respiratory alkalosis
what happens to HR and CO in pregnancy?
both go up