3/16 Reading Flashcards
teratogen effects of isotretinoin?
facial and ear anomalies, heart defects
what is MC cause of elevated AFP in pregnancy?
incorrect dating
what is imaging for wilms tumor?
US
what is elevated in neuroblastoma in kids?
VMA and metanephrines
4 features of tetralogy of fallot
overriding aorta
VSD
right ventricular hypertrophy
pulm stenosis
what imaging for tet of fallot? what is finding?
Xray…boot shaped heart
what can keep PDA open? what can close it?
prostaglandin E keeps open….indomethacin closes
what is truncus arteriosus?
one trunk comes from LV and RV
what is total anomalous pulmonary venous return?
pulm veins to SVC instead of left atrium
what happens in tricuspid atresis?
basically get failure of right side of heart and patient dependent on shunts
what is splitting of S2 like in ASD?
fixed wide splitting
murmur of ebstein anomaly?
holosystolic murmur like tricuspid regurgitation
three main features of osteogenesis imperfecta?
fragile bones/fractures, blue sclera and deafnes
what is issue in osteogenesis imperfecta?
collagen type 1
which bone tumor responds to NSAIDs?
osteoid osteoma
what is imaging finding of osteoid osteoma?
round central lucency with sclerotic margin
fever and URI that leads to slapped cheek rash?
parvo 19/5th disease
what is xray sign of epiglottisis?
thumbprint sign
what is treatment of diptheria?
antitoxin…abx dont work
two findings of B1 thiamine deficiency
wernicke and beriberi
3 findings of B2 riboflavin deficiency
angular chelosis,stomatitis and glossitis
findings of B3 or niacin deficiency
pellagra…dermatitis, diarrhea, dementia, dead
what is deficient in tay sachs?
hexoaminidase a
what are findings n tay sachs?
cherry red macula
ID
seizures
what is deficient in niemann pick disease?
sphingomyelinase
what are findings of niemann pick disease
cherry red macula
hepatosplenomegaly
neurodegeneration
what is deficiency in gaucher disease?
b glucocerebrosidase
findings of gaucher disease
hepatosplenomegaly
lytic lesions
gaucher cells
fabry disease presents with what?
peripheral neuropathy
what is deficient in fabry disease?
alpha galactosidase
what is deficient in krabbe disease?
galactocerebrosidase
features of krabbe disease
optic atrophy and developmental delay
what are neurotransmitter changes in bipolar?
high NE and serotonin
what is treatment of cyclothymic disorder?
mood stabilizers and psychotherapy
what antipsychotic least associated with weight gain?
aripiprazole
what antipsychotic has least risk for movement disorder?
quetiapine
which antipsychotic has strongest associatin with prolonged QT?
ziprasidone
three options for opiate withdrawal?
clonidine, methadone or buprenorphine
what happens to pupils in opiate intoxication/
pinpoint
rx of adjustment disorder?
psychotherapy
